Referências
Principais artigos
World Health Organization. Clinical care for survivors of Ebola virus disease: interim guidance. Apr 2016 [internet publication].Texto completo
World Health Organization. Guidelines for the management of pregnant and breastfeeding women in the context of Ebola virus disease. Feb 2020 [internet publication].Texto completo
World Health Organization. Infection prevention and control guideline for Ebola and Marburg diseases. May 2026 [internet publication].Texto completo
World Health Organization. Optimized supportive care for Ebola virus disease: clinical management standard operating procedures. Sep 2019 [internet publication].Texto completo
Lamontagne F, Fowler RA, Adhikari NK, et al. Evidence-based guidelines for supportive care of patients with Ebola virus disease. Lancet. 2018 Feb 17;391(10121):700-8.Texto completo Resumo
World Health Organization. Clinical management of patients with viral haemorrhagic fever: a pocket guide for front-line health workers. Feb 2016 [internet publication].Texto completo
World Health Organization. Therapeutics for Ebola virus disease - Democratic Republic of the Congo. Aug 2022 [internet publication].Texto completo
Artigos de referência
1. Centers for Disease Control and Prevention. Ebola disease basics. Jun 2026 [internet publication].Texto completo
2. Biedenkopf N, Bukreyev A, Chandran K, et al. Renaming of genera Ebolavirus and Marburgvirus to Orthoebolavirus and Orthomarburgvirus, respectively, and introduction of binomial species names within family Filoviridae. Arch Virol. 2023 Aug 3;168(8):220.Texto completo Resumo
3. World Health Organization. Ebola virus disease fact sheet. Apr 2025 [internet publication].Texto completo
4. Leroy EM, Gonzalez JP, Baize S. Ebola and Marburg haemorrhagic fever viruses: major scientific advances, but a relatively minor public health threat for Africa. Clin Microbiol Infect. 2011 Jul;17(7):964-76.Texto completo Resumo
5. Roddy P, Howard N, Van Kerkhove MD, et al. Clinical manifestations and case management of Ebola haemorrhagic fever caused by a newly identified virus strain, Bundibugyo, Uganda, 2007-2008. PLoS One. 2012 Dec 28;7(12):e52986.Texto completo Resumo
6. Towner JS, Sealy TK, Khristova ML, et al. Newly discovered ebola virus associated with hemorrhagic fever outbreak in Uganda. PLoS Pathog. 2008 Nov;4(11):e1000212.Texto completo Resumo
7. Formenty P, Hatz C, Le Guenno B, et al. Human infection due to Ebola virus, subtype Côte d'Ivoire: clinical and biologic presentation. J Infect Dis. 1999 Feb;179 Suppl 1:S48-53. Resumo
8. Feldmann H, Geisbert TW. Ebola haemorrhagic fever. Lancet. 2011 Mar 5;377(9768):849-62.Texto completo Resumo
9. Barrette RW, Metwally SA, Rowland JM, et al. Discovery of swine as a host for the Reston ebolavirus. Science. 2009 Jul 10;325(5937):204-6. Resumo
10. Karan LS, Makenov MT, Korneev MG, et al. Bombali virus in Mops condylurus bats, Guinea. Emerg Infect Dis. 2019 Sep;25(9):1774-5.Texto completo Resumo
11. Goldstein T, Anthony SJ, Gbakima A, et al. The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses. Nat Microbiol. 2018 Oct;3(10):1084-9. Resumo
12. Martell HJ, Masterson SG, McGreig JE, et al. Is the Bombali virus pathogenic in humans? Bioinformatics. 2019 Oct 1;35(19):3553-8.Texto completo Resumo
13. Swanepoel R, Smit SB, Rollin PE, et al. Studies of reservoir hosts for Marburg virus. Emerg Infect Dis. 2007 Dec;13(12):1847-51.Texto completo Resumo
14. McElroy AK, Erickson BR, Flietstra TD, et al. Ebola hemorrhagic fever: novel biomarker correlates of clinical outcome. J Infect Dis. 2014 Aug 15;210(4):558-66. Resumo
15. Mahanty S, Bray M. Pathogenesis of filoviral haemorrhagic fevers. Lancet Infect Dis. 2004 Aug;4(8):487-98.Texto completo Resumo
16. Yan T, Mu J, Qin E, et al. Clinical characteristics of 154 patients suspected of having Ebola disease in the Ebola holding centre of Jui government hospital in Sierra Leone during the 2014 Ebola outbreak. Eur J Microbiol Infect Dis. 2015 Oct;34(10):2089-95. Resumo
17. Kortepeter MG, Bausch DG, Bray M. Basic clinical and laboratory features of filoviral hemorrhagic fever. J Infect Dis. 2011 Nov;204 Suppl 3:S810-6. Resumo
18. Bwaka MA, Bonnet MJ, Calain P, et al. Ebola hemorrhagic fever in Kikwit, Democratic Republic of the Congo: clinical observations in 103 patients. J Infect Dis. 1999 Feb;179 Suppl 1:S1-7. Resumo
19. WHO Ebola Response Team. Ebola virus disease in West Africa: the first 9 months of the epidemic and forward projections. N Engl J Med. 2014 Oct 16;371(16):1481-95.Texto completo Resumo
20. Dallatomasinas S, Crestani R, Squire JS, et al. Ebola outbreak in rural West Africa: epidemiology, clinical features and outcomes. Trop Med Int Health. 2015 Apr;20(4):448-54. Resumo
21. Bah EI, Lamah MC, Fletcher T, et al. Clinical presentation of patients with Ebola virus disease in Conakry, Guinea. N Engl J Med. 2015 Jan 1;372(1):40-7.Texto completo Resumo
22. Chertow DS, Kleine C, Edwards JK, et al. Ebola virus disease in West Africa - clinical manifestations and management. N Engl J Med. 2014 Nov 27;371(22):2054-7.Texto completo Resumo
23. Schieffelin JS, Shaffer JG, Goba A, et al; KGH Lassa Fever Program; Viral Hemorrhagic Fever Consortium; WHO Clinical Response Team. Clinical illness and outcomes in patients with Ebola in Sierra Leone. N Engl J Med. 2014 Nov 27;371(22):2092-100.Texto completo Resumo
24. Nkoghe D, Leroy EM, Toung-Mve M, et al. Cutaneous manifestations of filovirus infections. Int J Dermatol. 2012 Sep;51(9):1037-43. Resumo
25. Report of an International Commission. Ebola haemorrhagic fever in Zaire, 1976. Bull World Health Organ. 1978;56(2):271-93.Texto completo Resumo
26. Peterson AT, Bauer JT, Mills JN. Ecologic and geographic distribution of filovirus disease. Emerg Infect Dis. 2004 Jan;10(1):40-7.Texto completo Resumo
27. Centers for Disease Control and Prevention. History of Ebola outbreaks [internet publication].Texto completo
28. Centers for Disease Control and Prevention. 2014: CDC laboratories produce first genomic sequence of Liberian Ebola. Mar 2019 [internet publication].Texto completo
29. Ansumana R, Jacobsen KH, Idris M, et al. Ebola in Freetown area, Sierra Leone - a case study of 581 patients. N Engl J Med. 2015 Feb 5;372(6):587-8.Texto completo Resumo
30. New York Times. How many Ebola patients have been treated outside of Africa? Jan 2015 [internet publication].Texto completo
31. World Health Organization. Disease outbreak news. Ebola disease caused by Sudan ebolavirus – Uganda. Jan 2023 [internet publication].Texto completo
32. World Health Organization. WHO Technical Advisory Group on therapeutics prioritization for Bundibugyo virus disease: meeting report, 20 and 26 May 2026. May 2026 [internet publication].Texto completo
33. World Health Organization. WHO Technical Advisory Group on candidate vaccine prioritization: meeting report, 19 and 25 May 2026. May 2026 [internet publication].Texto completo
34. World Health Organization. WHO emergency guidance on the use of licensed Ebola virus vaccine during Bundibugyo virus disease outbreaks, 28 May 2026. May 2026 [internet publication].Texto completo
35. Centers for Disease Control and Prevention. Ebola outbreak: current situation. Jun 2026 [internet publication].Texto completo
36. World Health Organization. Epidemic of Ebola disease caused by Bundibugyo virus in the Democratic Republic of the Congo and Uganda determined a public health emergency of international concern. May 2026 [internet publication].Texto completo
37. World Health Organization. WHO rapid risk assessment - Ebola disease caused by Bundibugyo virus, Democratic Republic of the Congo and Uganda v2. May 2026 [internet publication].Texto completo
38. Centers for Disease Control and Prevention. Ebola disease outbreak in the Democratic Republic of the Congo and Uganda. May 2026 [internet publication].Texto completo
39. World Health Organization. Ebola virus disease - Democratic Republic of the Congo. Dec 2025 [internet publication].Texto completo
40. World Health Organization. Sudan virus disease - Uganda. Apr 2025 [internet publication].Texto completo
41. World Health Organization. Disease outbreak news: Ebola virus disease - Democratic Republic of the Congo. Aug 2022 [internet publication].Texto completo
42. World Health Organization. Ebola virus disease - Democratic Republic of the Congo. Jul 2022 [internet publication].Texto completo
43. World Health Organization. Disease outbreak news. Ebola virus disease – Democratic Republic of the Congo. Dec 2021 [internet publication].Texto completo
44. World Health Organization. Disease outbreak news. Ebola virus disease – Guinea. Jun 2021 [internet publication].Texto completo
45. World Health Organization. Disease Outbreak News. Ebola - Democratic Republic of the Congo. May 2021 [internet publication].Texto completo
46. World Health Organization. Disease outbreak news: Ebola virus disease - Democratic Republic of the Congo. Nov 2020 [internet publication].Texto completo
47. World Health Organization. Ebola health update: north Kivu/Ituri, DRC, 2018-2020. Jul 2020 [internet publication].Texto completo
48. World Health Organization. WHO recommended criteria for declaring the end of the Ebola virus disease. Mar 2020 [internet publication].Texto completo
49. Peters CJ, LeDuc JW. An introduction to Ebola: the virus and the disease. J Infect Dis. 1999 Feb;179 Suppl 1:ix-xvi. Resumo
50. Swanepoel R, Leman PA, Burt FJ, et al. Experimental inoculation of plants and animals with Ebola virus. Emerg Infect Dis. Oct-Dec 1996;2(4):321-5.Texto completo Resumo
51. Reiter P, Turell M, Coleman R, et al. Field investigations of an outbreak of Ebola hemorrhagic fever, Kikwit, Democratic Republic of the Congo, 1995: arthropod studies. J Infect Dis. 1999 Feb;179 Suppl 1:S148-54. Resumo
52. Pigott DM, Golding N, Mylne A, et al. Mapping the zoonotic niche of Ebola virus disease in Africa. Elife. 2014 Sep 8;3:e04395.Texto completo Resumo
53. Dowell SF, Mukunu R, Ksiazek TG, et al. Transmission of Ebola hemorrhagic fever: a study of risk factors in family members, Kikwit, Democratic Republic of the Congo, 1995. Commission de Lutte contre les Epidémies à Kikwit. J Infect Dis. 1999 Feb;179 Suppl 1:S87-91. Resumo
54. Bausch DG, Towner JS, Dowell SF, et al. Assessment of the risk of Ebola virus transmission from bodily fluids and fomites. J Infect Dis. 2007 Nov 15;196 Suppl 2:S142-7. Resumo
55. Osterholm MT, Moore KA, Kelley NS, et al. Transmission of Ebola viruses: what we know and what we do not know. MBio. 2015 Feb 19;6(2):e00137.Texto completo Resumo
56. Kreuels B, Wichmann D, Emmerich P, et al. A case of severe Ebola virus infection complicated by gram-negative septicemia. N Engl J Med. 2014 Dec 18;371(25):2394-401.Texto completo Resumo
57. World Health Organization. Sierra Leone: a traditional healer and a funeral. 2015 [internet publication].Texto completo
58. Lau MS, Dalziel BD, Funk S, et al. Spatial and temporal dynamics of superspreading events in the 2014-2015 West Africa Ebola epidemic. Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2337-42.Texto completo Resumo
59. Emond RT, Evans B, Bowen ET, et al. A case of Ebola virus infection. Br Med J. 11977 Aug 27;2(6086):541-4.Texto completo Resumo
60. Rowe AK, Bertolli J, Khan AS, et al. Clinical, virologic, and immunologic follow-up of convalescent Ebola hemorrhagic fever patients and their household contacts, Kikwit, Democratic Republic of the Congo. Commission de Lutte contre les Epidémies à Kikwit. J Infect Dis. 1999 Feb;179 Suppl 1:S28-35. Resumo
61. World Health Organization. Clinical care for survivors of Ebola virus disease: interim guidance. Apr 2016 [internet publication].Texto completo
62. Rogstad KE, Tunbridge A. Ebola virus as sexually transmitted infection. Curr Opin Infect Dis. 2015 Feb;28(1):83-5. Resumo
63. Sonnenberg P, Field P. Sexual and mother-to-child transmission of Ebola virus in the post-convalescent period. Clin Infect Dis. 2015 Mar 15;60(6):974-5. Resumo
64. Mate SE, Kugelman JR, Nyenswah TG, et al. Molecular evidence of sexual transmission of Ebola virus. N Engl J Med. 2015 Dec 17;373(25):2448-54.Texto completo Resumo
65. Crozier I. Ebola virus RNA in the semen of male survivors of Ebola virus disease: the uncertain gravitas of a privileged persistence. J Infect Dis. 2016 Nov 15;214(10):1467-9. Resumo
66. Thorson A, Formenty P, Lofthouse C, et al. Systematic review of the literature on viral persistence and sexual transmission from recovered Ebola survivors: evidence and recommendations. BMJ Open. 2016 Jan 7;6(1):e008859.Texto completo Resumo
67. Rodriguez LL, De Roo A, Guimard Y, et al. Persistence and genetic stability of Ebola virus during the outbreak in Kikwit, Democratic Republic of the Congo, 1995. J Infect Dis. 1999 Feb;179 Suppl 1:S170-6. Resumo
68. Centers for Disease Control and Prevention. Caring for Ebola disease survivors in the US. Mar 2025 [internet publication].Texto completo
69. Judson S, Prescott J, Munster V. Understanding Ebola virus transmission. Viruses. 2015 Feb 3;7(2):511-21.Texto completo Resumo
70. Beeching NJ, Fletcher TE, Hill DR, et al. Travellers and viral haemorrhagic fevers: what are the risks? Int J Antimicrob Agents. 2010 Nov;36 Suppl 1:S26-35. Resumo
71. Carroll M, Matthews DA, Hiscox JA, et al. Temporal and spatial analysis of the 2014–2015 Ebola virus outbreak in West Africa. Nature. 2015 Aug 6;524(7563):97-101.Texto completo Resumo
72. Gire SK, Goba A, Andersen KG, et al. Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak. Science. 2014 Sep 12;345(6202):1369-72.Texto completo Resumo
73. Muzembo BA, Kitahara K, Mitra D, et al. The basic reproduction number (R(0)) of Ebola virus disease: a systematic review and meta-analysis. Travel Med Infect Dis. 2024 Jan-Feb;57:102685.Texto completo Resumo
74. Sharma N, Cappell MS. Gastrointestinal and hepatic manifestations of Ebola virus infection. Dig Dis Sci. 2015 Sep;60(9):2590-603. Resumo
75. Ramanan P, Shabman RS, Brown CS, et al. Filoviral immune evasion mechanisms. Viruses. 2011 Sep;3(9):1634-49.Texto completo Resumo
76. Ramanan P, Edwards MR, Shabman RS, et al. Structural basis for Marburg virus VP35-mediated immune evasion mechanisms. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20661-6.Texto completo Resumo
77. Ansari AA. Clinical features and pathobiology of Ebolavirus infection. J Autoimmun. 2014 Dec;55:1-9. Resumo
78. Martines RB, Ng DL, Greer PW, et al. Tissue and cellular tropism, pathology and pathogenesis of Ebola and Marburg viruses. J Pathol. 2015 Jan;235(2):153-74. Resumo
79. Falasca L, Agrati C, Petrosillo N, et al. Molecular mechanisms of Ebola virus pathogenesis: focus on cell death. Cell Death Differ. 2015 Aug;22(8):1250-9.Texto completo Resumo
80. Fletcher T, Fowler RA, Beeching NJ. Understanding organ dysfunction in Ebola virus disease. Intensive Care Med. 2014 Dec;40(12):1936-9. Resumo
81. Sanchez A, Lukwiya M, Bausch D, et al. Analysis of human peripheral blood samples from fatal and nonfatal cases of Ebola (Sudan) hemorrhagic fever: cellular responses, virus load, and nitric oxide levels. J Virol. 2004 Oct;78(19):10370-7.Texto completo Resumo
82. Rougeron V, Feldmann H, Grard G, et al. Ebola and Marburg haemorrhagic fever. J Clin Virol. 2015 Mar;64:111-9. Resumo
83. Zapata JC, Cox D, Salvato MS. The role of platelets in the pathogenesis of viral hemorrhagic fevers. PLoS Negl Trop Dis. 2014 Jun 12;8(6):e2858.Texto completo Resumo
84. Leroy EM, Baize S, Volchkov VE, et al. Human asymptomatic Ebola infection and strong inflammatory response. Lancet. 2000 Jun 24;355(9222):2210-5.Texto completo Resumo
85. Ruibal P, Oestereich L, Lüdtke A, et al. Unique human immune signature of Ebola virus disease in Guinea. Nature. 2016 May 5;533(7601):100-4.Texto completo Resumo
86. WHO Ebola Response Team. Ebola virus disease among children in West Africa. N Engl J Med. 2015 Mar 26;372(13):1274-7.Texto completo Resumo
87. Nielsen CF, Kidd S, Sillah AR, et al. Improving burial practices and cemetery management during an Ebola virus disease epidemic - Sierra Leone, 2014. MMWR Morb Mortal Wkly Rep. 2015 Jan 16;64(1):20-7.Texto completo Resumo
88. Georges-Courbot MC, Sanchez A, Lu CY, et al. Isolation and phylogenetic characterization of Ebola viruses causing different outbreaks in Gabon. Emerg Infect Dis. Jan-Mar 1997;3(1):59-62.Texto completo Resumo
89. Strauss S. Ebola research fueled by bioterrorism threat. CMAJ. 2014 Nov 4;186(16):1206.Texto completo Resumo
90. Borio L, Inglesby T, Peters CJ, et al. Hemorrhagic fever viruses as biological weapons: medical and public health management. JAMA. 2002 May 8;287(18):2391-405. Resumo
91. Centers for Disease Control and Prevention. Viral hemorrhagic fevers - guidance for personal protective equipment (PPE). May 2024 [internet publication].Texto completo
92. Jacobs M, Aarons E, Bhagani S, et al. Post-exposure prophylaxis against Ebola virus disease with experimental antiviral agents: a case-series of health-care workers. Lancet Infect Dis. 2015 Nov;15(11):1300-4.Texto completo Resumo
93. World Health Organization. WHO prequalifies Ebola vaccine, paving the way for its use in high-risk countries. Nov 2019 [internet publication].Texto completo
94. Malenfant JH, Joyce A, Choi MJ, et al. Use of Ebola vaccine: expansion of recommendations of the Advisory Committee on Immunization Practices to include two additional populations - United States, 2021. MMWR Morb Mortal Wkly Rep. 2022 Feb 25;71(8):290-2.Texto completo Resumo
95. Conteh MA, Goldstein ST, Wurie HR, et al. Clinical surveillance and evaluation of suspected Ebola cases in a vaccine trial during an Ebola epidemic: the Sierra Leone trial to introduce a vaccine against Ebola. J Infect Dis. 2018 May 18;217(suppl_1):S33-S39.Texto completo Resumo
96. Henao-Restrepo AM, Camacho A, Longini IM, et al. Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!). Lancet. 2017 Feb 4;389(10068):505-18.Texto completo Resumo
97. World Health Organization. Guidelines for the management of pregnant and breastfeeding women in the context of Ebola virus disease. Feb 2020 [internet publication].Texto completo
98. Centers for Disease Control and Prevention. Clinical guidance for Ebola disease. May 2026 [internet publication].Texto completo
99. Centers for Disease Control and Prevention. Clinical features of Ebola disease. May 2026 [internet publication].Texto completo
100. UK Health Security Agency. Ebola disease outbreak in the Democratic Republic of the Congo and Uganda (Bundibugyo virus). Jun 2026 [internet publication].Texto completo
101. Fletcher TE, Brooks TJ, Beeching NJ. Ebola and other viral haemorrhagic fevers. BMJ. 2014 Aug 11;349:g5079.Texto completo Resumo
102. World Health Organization. Infection prevention and control guideline for Ebola and Marburg diseases. May 2026 [internet publication].Texto completo
103. Mendelson M, Han PV, Vincent P, et al. Regional variation in travel-related illness acquired in Africa, March 1997-May 2011. Emerg Infect Dis. 2014 Apr;20(4):532-41.Texto completo Resumo
104. Hunt L, Gupta-Wright A, Simms V, et al. Clinical presentation, biochemical, and haematological parameters and their association with outcome in patients with Ebola virus disease: an observational cohort study. Lancet Infect Dis. 2015 Nov;15(11):1292-9. Resumo
105. World Health Organization. Case definition recommendations for Ebola or Marburg virus diseases. Aug 2014 [internet publication].Texto completo
106. Rojek AM, Salam A, Ragotte RJ, et al. A systematic review and meta-analysis of patient data from the West Africa (2013-16) Ebola virus disease epidemic. Clin Microbiol Infect. 2019 Nov;25(11):1307-14.Texto completo Resumo
107. Glynn JR. Age-specific incidence of Ebola virus disease. Lancet. 2015 Aug 1;386(9992):432.Texto completo Resumo
108. Mupere E, Kaducu OF, Yoti Z. Ebola haemorrhagic fever among hospitalised children and adolescents in northern Uganda: epidemiologic and clinical observations. Afr Health Sci. 2001 Dec;1(2):60-5.Texto completo Resumo
109. Peacock G, Uyeki TM, Rasmussen SA. Ebola virus disease and children: what pediatric health care professionals need to know. JAMA Pediatr. 2014 Dec;168(12):1087-8.Texto completo Resumo
110. Fitzgerald F, Naveed A, Wing K, et al. Ebola virus disease in children, Sierra Leone, 2014-2015. Emerg Infect Dis. 2016 Oct;22(10):1769-77.Texto completo Resumo
111. Shah T, Greig J, van der Plas LM, et al. Inpatient signs and symptoms and factors associated with death in children aged 5 years and younger admitted to two Ebola management centres in Sierra Leone, 2014: a retrospective cohort study. Lancet Glob Health. 2016 Jul;4(7):e495-501.Texto completo Resumo
112. Dananché C, Bénet T, Vanhems P. Ebola: fever definitions might delay detection in non-epidemic areas. Lancet. 2014 Dec;168(12):1087-8.Texto completo Resumo
113. Lado M, Howlett P. Ebola virus disease in children: towards a better clinical picture and improved management. Lancet Glob Health. 2016 Jul;4(7):e436-7.Texto completo Resumo
114. Lopaz MA, Amela C, Ordobas M, et al. First secondary case of Ebola outside Africa: epidemiological characteristics and contact monitoring, Spain, September to November 2014. Euro Surveill. 2015 Jan 8;20(1):21003.Texto completo Resumo
115. Lyon GM, Mehta AK, Varkey JB, et al; Emory Serious Communicable Diseases Unit. Clinical care of two patients with Ebola virus disease in the United States. N Engl J Med. 2014 Dec 18;371(25):2402-9.Texto completo Resumo
116. World Health Organization. Exit screening at airports, ports and land crossings: interim guidance for Ebola virus disease. Nov 2014 [internet publication].Texto completo
117. Petrosillo N, Nicastri E, Lanini S, et al. Ebola virus disease complicated with viral interstitial pneumonia: a case report. BMC Infect Dis. 2015 Oct 16;15:432.Texto completo Resumo
118. World Health Organization. Diagnostic testing for Ebola and Marburg virus diseases: interim guidance, 20 December 2024. Jan 2025 [internet publication].Texto completo
119. Cherpillod P, Schibler M, Vieille G, et al. Ebola virus disease diagnosis by real-time RT-PCR: a comparative study of 11 different procedures. J Clin Virol. 2016 Apr;77:9-14.Texto completo Resumo
120. Towner JS, Rollin PE, Bausch DG, et al. Rapid diagnosis of Ebola hemorrhagic fever by reverse transcription-PCR in an outbreak setting and assessment of patient viral load as a predictor of outcome. J Virol. 2004 Apr;78(8):4330-41.Texto completo Resumo
121. Boggild AK, Esposito DH, Kozarsky PE, et al. Differential diagnosis of illness in travelers arriving from Sierra Leone, Liberia, or Guinea: a cross-sectional study from the GeoSentinel Surveillance Network. Ann Intern Med. 2015 Jun 2;162(11):757-64. Resumo
122. Centers for Disease Control and Prevention. Guidance for malaria diagnosis in patients with suspected orthoebolavirus or orthomarburgvirus infection in the United States. Sep 2024 [internet publication].Texto completo
123. McElroy AK, Erickson BR, Flietstra TD, et al. Biomarker correlates of survival in pediatric patients with ebola virus disease. Emerg Infect Dis. 2014 Oct;20(10):1683-90.Texto completo Resumo
124. Fowler RA, Fletcher T, Fischer WA 2nd, et al. Caring for critically ill patients with Ebola virus disease. Perspectives from West Africa. Am J Respir Crit Care Med. 2014 Oct 1;190(7):733-7. Resumo
125. Rollin PE, Bausch DG, Sanchez A. Blood chemistry measurements and D-Dimer levels associated with fatal and nonfatal outcomes in humans infected with Sudan Ebola virus. J Infect Dis. 2007 Nov 15;196 Suppl 2:S364-71. Resumo
126. Dickson SJ, Clay KA, Adam M, et al. Enhanced case management can be delivered for patients with EVD in Africa: experience from a UK military Ebola treatment centre in Sierra Leone. J Infect. 2018 Apr;76(4):383-92.Texto completo Resumo
127. Lamb L, Robson J, Ardley C, et al. Bacterial co-infection is rare in patients with Ebola virus disease in a military Ebola virus disease treatment unit in Sierra Leone. J Infect. 2015 Sep;71(3):406-7. Resumo
128. Auffermann WF, Kraft CS, Vanairsdale S, et al. Radiographic imaging for patients with contagious infectious diseases: how to acquire chest radiographs of patients infected with the Ebola virus. AJR Am J Roentgenol. 2015 Jan;204(1):44-8. Resumo
129. Butler D. Ebola experts seek to expand testing. Nature. 2014 Dec 11;516(7530):154-5. Resumo
130. Burd EM. Ebola virus: a clear and present danger. J Clin Microbiol. 2015 Jan;53(1):4-8.Texto completo Resumo
131. Hoenen T, Groseth A, Rosenke K, et al. Nanopore sequencing as a rapidly deployable ebola outbreak tool. Emerg Infect Dis. 2016 Feb;22(2):331-4.Texto completo Resumo
132. Tsang MK, Ye W, Wang G, et al. Ultrasensitive detection of ebola virus oligonucleotide based on upconversion nanoprobe/nanoporous membrane system. ACS Nano. 2016 Jan 26;10(1):598-605. Resumo
133. Quick J, Loman NJ, Duraffour S, et al. Real-time, portable genome sequencing for Ebola surveillance. Nature. 2016 Feb 11;530(7589):228-32Texto completo Resumo
134. Semper AE, Broadhurst MJ, Richards J, et al. Performance of the GeneXpert Ebola assay for diagnosis of Ebola virus disease in Sierra Leone: a field evaluation study. PLoS Med. 2016 Mar 29;13(3):e1001980.Texto completo Resumo
135. Moshirfar M, Fenzl CR, Li Z. What we know about ocular manifestations of Ebola. Clin Ophthalmol. 2014 Nov 21;8:2355-7.Texto completo Resumo
136. Lado M, Walker N, Baker P, et al. Clinical features of patients isolated for suspected Ebola virus disease at Connaught Hospital, Freetown, Sierra Leone: a retrospective cohort study. Lancet Infect Dis. 2015 Sep;15(9):1024-33. Resumo
137. Muzembo BA, Kitahara K, Ohno A, et al. Rapid diagnostic tests versus RT-PCR for Ebola virus infections: a systematic review and meta-analysis. Bull World Health Organ. 2022 Jul 1;100(7):447-58.Texto completo Resumo
138. Hensley LE, Wahl-Jensen V, McCormick JB, et al. Viral hemorrhagic fevers. In: Cohen J, Powderly W, Opal S, eds. Infectious Diseases. 3rd ed. Maryland Heights, MO: Mosby; 2010:1231-7.
139. Hartskeerl RA, Collares-Pereira M, Ellis WA. Emergence, control and re-emerging leptospirosis: dynamics of infection in the changing world. Clin Microbiol Infect. 2011 Apr;17(4):494-501.Texto completo Resumo
140. Centers for Disease Control and Prevention. Viral hemorrhagic fever (VHF): 2025 case definition. Oct 2024 [internet publication].Texto completo
141. UK Health Security Agency. Epidemiological case definitions for Ebola disease and Marburg disease. Sep 2025 [internet publication].Texto completo
142. World Health Organization. Implementation of border health and international travel-related temporary recommendations issued by the Director-General of WHO to states parties not sharing land borders with areas with documented Bundibugyo virus detection. May 2026 [internet publication].Texto completo
143. Centers for Disease Control and Prevention. Interim guidance for public health assessment and management of travelers from countries affected by the 2026 Ebola outbreak. Jun 2026 [internet publication].Texto completo
144. Wolf T, Kann G, Becker S, et al. Severe Ebola virus disease with vascular leakage and multiorgan failure: treatment of a patient in intensive care. Lancet. 2015 Apr 11;385(9976):1428-35.Texto completo Resumo
145. Parra JM, Salmerón OJ, Velasco M. The first case of Ebola virus disease acquired outside Africa. N Engl J Med. 2014 Dec 18;371(25):2439-40.Texto completo Resumo
146. Uyeki TM, Mehta AK, Davey RT Jr, et al. Clinical management of Ebola virus disease in the United States and Europe. N Engl J Med. 2016 Feb 18;374(7):636-46.Texto completo Resumo
147. Zacharowski K, Brodt HR, Wolf T. Medical treatment of an Ebola-infected doctor -ethics over costs? Lancet. 2015 Feb 21;385(9969):685.Texto completo Resumo
148. Solano T, Gilbert GL, Kerridge IH, et al. Ethical considerations in the management of Ebola virus disease. Med J Aust. 2015 Aug 17;203(4):193-5e.1. Resumo
149. Jacobs M, Beadsworth M, Schmid M, et al. Provision of care for Ebola. Lancet. 2014 Dec 13;384(9960):2105-6.Texto completo Resumo
150. Decker BK, Sevransky JE, Barrett K, et al. Preparing for critical care services to patients with ebola. Ann Intern Med. 2014 Dec 2;161(11):831-2.Texto completo Resumo
151. Canadian Critical Care Society; Canadian Association of Emergency Physicians; Association of Medical Microbiology and Infectious Diseases of Canada. Ebola clinical care guidelines: a guide for clinicians in Canada. October 2014 [internet publication].Texto completo
152. Rees PS, Lamb LE, Nicholson-Roberts TC, et al. Safety and feasibility of a strategy of early central venous catheter insertion in a deployed UK military Ebola virus disease treatment unit. Intensive Care Med. 22015 May;41(5):735-43. Resumo
153. World Health Organization. Optimized supportive care for Ebola virus disease: clinical management standard operating procedures. Sep 2019 [internet publication].Texto completo
154. Lamontagne F, Fowler RA, Adhikari NK, et al. Evidence-based guidelines for supportive care of patients with Ebola virus disease. Lancet. 2018 Feb 17;391(10121):700-8.Texto completo Resumo
155. Perner A, Fowler R, Bellomo R, et al. Ebola care and research protocols. Intensive Care Med. 2015 Jan;41(1):111-4. Resumo
156. Roberts I, Perner A. Ebola virus disease: clinical care and patient-centred research. Lancet. 2014 Dec 6;384(9959):2001-2.Texto completo Resumo
157. Clay KA, Johnston AM, Moore A, et al. Targeted electrolyte replacement in patients with Ebola virus disease. Clin Infect Dis. 2015 Sep 15;61(6):1030-1. Resumo
158. World Health Organization. Manual for the care and management of patients in Ebola care units/community care centres: interim emergency guidance. January 2015 [internet publication].Texto completo
159. Kendall RE, Gosser RA, Schulz LT, et al. Anti-diarrheal medication use in the treatment of Ebola virus-induced diarrhea. Travel Med Infect Dis. 2015 Mar-Apr;13(2):205-6. Resumo
160. Chertow DS, Uyeki TM, DuPont HL. Loperamide therapy for voluminous diarrhea in Ebola virus disease. J Infect Dis. 2015 Apr 1;211(7):1036-7. Resumo
161. World Health Organization. Clinical management of patients with viral haemorrhagic fever: a pocket guide for front-line health workers. Feb 2016 [internet publication].Texto completo
162. Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2021. Crit Care Med. 2021 Nov 1;49(11): e1063-e1143.Texto completo Resumo
163. Wada H, Thachil J, Di Nisio M, et al. Guidance for diagnosis and treatment of DIC from harmonization of the recommendations from three guidelines. J Thromb Haemost. 2013 Feb 4;11(4):761-7.Texto completo Resumo
164. Warren T, Jordan R, Lo M, et al. Nucleotide prodrug GS-5734 is a broad-spectrum Filovirus inhibitor that provides complete therapeutic protection against the development of Ebola Virus Disease (EVD) in infected non-human primates. Late breaker abstract 2. Presented at IDWeek. San Diego, 2015.
165. Connor MJ Jr, Kraft C, Mehta AK, et al. Successful delivery of RRT in Ebola virus disease. J Am Soc Nephrol. 2015 Jan;26(1):31-7. Resumo
166. World Health Organization. Interim guidance: potential Ebola therapies and vaccines. Nov 2014 [internet publication].Texto completo
167. Kreil TR. Treatment of Ebola virus infection with antibodies from reconvalescent donors. Emerg Infect Dis. 2015 Mar;21(3):521-3.Texto completo Resumo
168. Gutfraind A, Myers LA. Evaluating large-scale blood transfusion therapy for the current Ebola epidemic in Liberia. J Infect Dis. 22015 Apr 15;211(8):1262-7. Resumo
169. van Griensven J, Edwards T, de Lamballerie X, et al. Evaluation of convalescent plasma for Ebola virus disease in Guinea. N Engl J Med. 2016 Jan 7;374(1):33-42.Texto completo Resumo
170. van Griensven J, De Weiggheleire A, Delamou A, et al. The use of Ebola convalescent plasma to treat Ebola virus disease in resource-constrained settings: a perspective from the field. Clin Infect Dis. 2016 Jan 1;62(1):69-74.Texto completo Resumo
171. World Health Organization. Therapeutics for Ebola virus disease - Democratic Republic of the Congo. Aug 2022 [internet publication].Texto completo
172. Mulangu S, Dodd LE, Davey RT Jr, et al. A randomized, controlled trial of Ebola virus disease therapeutics. N Engl J Med. 2019 Dec 12;381(24):2293-303.Texto completo Resumo
173. Gao Y, Zhao Y, Guyatt G, et al. Effects of therapies for Ebola virus disease: a systematic review and network meta-analysis. Lancet Microbe. 2022 Sep;3(9):e683-92.Texto completo Resumo
174. Foeller ME, Carvalho Ribeiro do Valle C, Foeller TM, et al. Pregnancy and breastfeeding in the context of Ebola: a systematic review. Lancet Infect Dis. 2020 Jul;20(7):e149-58.Texto completo Resumo
175. Mupapa K, Mukundu W, Bwaka MA, et al. Ebola hemorrhagic fever and pregnancy. J Infect Dis. 1999 Feb;179 Suppl 1:S11-2. Resumo
176. Baggi FM, Taybi A, Kurth A, et al. Management of pregnant women infected with Ebola virus in a treatment centre in Guinea, June 2014. Euro Surveill. 2014 Dec 11;19(49):20983.Texto completo Resumo
177. Jamieson DJ, Uyeki TM, Callaghan WM, et al. What obstetrician-gynecologists should know about Ebola: a perspective from the Centers for Disease Control and Prevention. Obstet Gynecol. 2014 Nov;124(5):1005-10. Resumo
178. Association of Women's Health, Obstetric and Neonatal Nurses. Ebola: caring for pregnant and postpartum women and newborns in the United States: AWHONN practice brief number 3. J Obstet Gynecol Neonat Nurs. 2015 Jan-Feb;44(1):164-5Texto completo Resumo
179. Kitching A, Walsh A, Morgan D. Ebola in pregnancy: risk and clinical outcomes. BJOG. 2015 Feb;122(3):287. Resumo
180. Olupot-Olupot P. Ebola in children: epidemiology, clinical features, diagnosis and outcomes. Pediatr Infect Dis J. 2015 Mar;34(3):314-6. Resumo
181. Herberg JA, Emonts M, Jacobs M, et al. UK preparedness for children with Ebola infection. Arch Dis Child. 2015 May;100(5):421-3. Resumo
182. Eriksson CO, Uyeki TM, Christian MD, et al. Care of the child with Ebola virus disease. Pediatr Crit Care Med. 2015 Feb;16(2):97-103. Resumo
183. Bishop BM. Potential and emerging treatment options for Ebola virus disease. Ann Pharmacother. 2015 Feb;49(2):196-206. Resumo
184. Goodman JL. Studying "secret serums": toward safe, effective Ebola treatments. N Engl J Med. 2014 Sep 18;371(12):1086-9.Texto completo Resumo
185. Zhang Y, Li D, Jin X, et al. Fighting Ebola with ZMapp: spotlight on plant-made antibody. Sci China Life Sci. 2014 Oct;57(10):987-8. Resumo
186. Qiu X, Wong G, Audet J, et al. Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp. Nature. 2014 Oct 2;514(7520):47-53.Texto completo Resumo
187. Furuta Y, Takahashi K, Shiraki K, et al. T-705 (favipiravir) and related compounds: novel broad-spectrum inhibitors of RNA viral infections. Antiviral Res. 2009 Jun;82(3):95-102. Resumo
188. Sissoko D, Laouenan C, Folkesson E, et al. Experimental treatment with favipiravir for Ebola virus disease (the JIKI trial): a historically controlled, single-arm proof-of-concept trial in Guinea. PLoS Med. 2016 Mar 1;13(3):e1001967.Texto completo Resumo
189. Izudi J, Bajunirwe F. Case fatality rate for Ebola disease, 1976-2022: a meta-analysis of global data. J Infect Public Health. 2024 Jan;17(1):25-34.Texto completo Resumo
190. WHO Ebola Response Team. Ebola virus disease among male and female persons in West Africa. N Engl J Med. 2016 Jan 7;374(1):96-8.Texto completo Resumo
191. Sadek RF, Khan AS, Stevens G, et al. Ebola hemorrhagic fever, Democratic Republic of the Congo, 1995: determinants of survival. J Infect Dis. 1999 Feb;179 Suppl 1:S24-7. Resumo
192. Lauck M, Bailey AL, Andersen KG, et al. GB virus C co-infections in West African Ebola patients. J Virol. 2015 Feb;89(4):2425-9.Texto completo Resumo
193. Deen GF, Broutet N, Xu W, et al. Ebola RNA persistence in semen of Ebola virus disease survivors - final report. N Engl J Med. 2017 Oct 12;377(15):1428-37.Texto completo Resumo
194. Soka MJ, Choi MJ, Baller A, et al. Prevention of sexual transmission of Ebola in Liberia through a national semen testing and counselling programme for survivors: an analysis of Ebola virus RNA results and behavioural data. Lancet Glob Health. 2016 Oct;4(10):e736-43.Texto completo Resumo
195. Etard JF, Sow MS, Leroy S, et al; Postebogui Study Group. Multidisciplinary assessment of post-Ebola sequelae in Guinea (Postebogui): an observational cohort study. Lancet Infect Dis. 2017 May;17(5):545-52.Texto completo Resumo
196. Muwonge H, Nasimiyu C, Bakamutumaho B, et al. Long-term clinical sequelae among Sudan ebolavirus disease survivors 2 years post-infection: a matched cohort study. BMC Med. 2025 Jul 18;23(1):432.Texto completo Resumo
197. PREVAIL III Study Group, Sneller MC, Reilly C, et al. A longitudinal study of Ebola sequelae in Liberia. N Engl J Med. 2019 Mar 7;380(10):924-34.Texto completo Resumo
198. Chughtai AA, Barnes M, Macintyre CR. Persistence of Ebola virus in various body fluids during convalescence: evidence and implications for disease transmission and control. Epidemiol Infect. 2016 Jun;144(8):1652-60.Texto completo Resumo
199. Mattia JG, Vandy MJ, Chang JC, et al. Early clinical sequelae of Ebola virus disease in Sierra Leone: a cross-sectional study. Lancet Infect Dis. 2016 Mar;16(3):331-8. Resumo
200. Scott JT, Sesay FR, Massaquoi TA, et al. Post-Ebola syndrome, Sierra Leone. Emerg Infect Dis. 2016 Apr;22(4):641-6.Texto completo Resumo
201. Tiffany A, Vetter P, Mattia J, et al. Ebola virus disease complications as experienced by survivors in Sierra Leone. Clin Infect Dis. 2016 Jun 1;62(11):1360-6.Texto completo Resumo
202. Kaweesa RE, Katende JS, Wayesu RR, et al. Resilience and residuals beyond containment - the hidden burden of Bundibugyo Ebola virus survivorship sixteen years on: a cross-sectional observational study. New Microbes New Infect. 2026 Feb;69:101685.Texto completo Resumo
203. Shantha JG, Yeh S, Nguyen QD. Ebola virus disease and the eye. Curr Opin Ophthalmol. 2016 Nov;27(6):538-44. Resumo
204. Shantha JG, Crozier I, Hayek BR, et al. Ophthalmic manifestations and causes of vision impairment in Ebola virus disease survivors in Monrovia, Liberia. Ophthalmology. 2017 Feb;124(2):170-7. Resumo
205. Varkey JB, Shanth JG, Crozier I, et al. Persistence of Ebola virus in ocular fluid during convalescence. N Engl J Med. 2015 Jun 18;372(25):2423-7. Resumo
206. Chancellor JR, Padmanabhan SP, Greenough TC, et al. Uveitis and systemic inflammatory markers in convalescent phase of Ebola virus disease. Emerg Infect Dis. 2016 Feb;22(2):295-7.Texto completo Resumo
207. Steptoe PJ, Scott JT, Baxter JM, et al. Novel retinal lesion in Ebola survivors, Sierra Leone, 2016. Emerg Infect Dis. 2017 Jul;23(7):1102-9.Texto completo Resumo
208. Thom R, Tipton T, Strecker T, et al. Longitudinal antibody and T cell responses in Ebola virus disease survivors and contacts: an observational cohort study. Lancet Infect Dis. 2021 Apr;21(4):507-16.Texto completo Resumo
209. Jacobs M, Rodger A, Bell DJ, et al. Late Ebola virus relapse causing meningoencephalitis: a case report. Lancet. 2016 Jul 30;388(10043):498-503.Texto completo Resumo
210. Howlett P, Brown C, Helderman T, et al. Ebola virus disease complicated by late-onset encephalitis and polyarthritis, Sierra Leone. Emerg Infect Dis. 2016 Jan;22(1):150-2.Texto completo Resumo
211. Dokubo EK, Wendland A, Mate SE, et al. Persistence of Ebola virus after the end of widespread transmission in Liberia: an outbreak report. Lancet Infect Dis. 2018 Sep;18(9):1015-24.Texto completo Resumo
212. Locsin RC, Barnard A, Matua AG, et al. Surviving Ebola: understanding experience through artistic expression. Int Nurs Rev. 2003 Sep;50(3):156-66. Resumo
213. De Roo A, Ado B, Rose B, et al. Survey among survivors of the 1995 Ebola epidemic in Kikwit, Democratic Republic of Congo: their feelings and experiences. Trop Med Int Health. 1998 Nov;3(11):883-5. Resumo
214. Cénat JM, Felix N, Blais-Rochette C, et al. Prevalence of mental health problems in populations affected by the Ebola virus disease: a systematic review and meta-analysis. Psychiatry Res. 2020 Apr 29;289:113033.Texto completo Resumo
215. James PB, Wardle J, Steel A, et al. Post-Ebola psychosocial experiences and coping mechanisms among Ebola survivors: a systematic review. Trop Med Int Health. 2019 Jun;24(6):671-91.Texto completo Resumo
216. World Health Organization. Use of convalescent whole blood or plasma collected from patients recovered from Ebola virus disease for transfusion, as an empirical treatment during outbreaks. Sep 2014 [internet publication].Texto completo
217. Wong KK, Davey RT Jr, Hewlett AL, et al. Use of post-exposure prophylaxis after occupational exposure to Zaire ebolavirus. Clin Infect Dis. 2016 Aug 1;63(3):376-9. Resumo
218. Fischer WA Nd, Vetter P, Bausch DG, et al. Ebola virus disease: an update on post-exposure prophylaxis. Lancet Infect Dis. 2017 Nov 15. pii: S1473-3099(17)30677-1.Texto completo Resumo
219. Savini H, Ficko C, Simon F. Post-exposure prophylaxis in Ebola virus disease: don't forget the psychological factors. Lancet Infect Dis. 2018 Apr;18(4):378.Texto completo Resumo
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