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最后审阅: 21 Oct 2024
最后更新: 04 Oct 2024
04 Oct 2024

埃博拉病毒种的重新命名

国际病毒分类委员会(International Committee on Taxonomy of Viruses, ICTV)已将埃博拉病毒属改名为正埃博拉病毒。

近年来,埃博拉病毒属(包括 6 个种)与埃博拉病毒(扎伊尔型埃博拉病毒种的病毒名)相混淆,造成了命名上的混乱,从而引发了这一变化。

现正埃博拉病毒属包含以下重命名种:

  • 扎伊尔型正埃博拉病毒(orthoebolavirus zairense;旧称扎伊尔型埃博拉病毒)

  • 苏丹型正埃博拉病毒(orthoebolavirus sudanense;旧称苏丹型埃博拉病毒)

  • 塔伊森林型正埃博拉病毒(orthoebolavirus taiense;旧称塔伊森林型埃博拉病毒)

  • 本迪布焦型正埃博拉病毒(orthoebolavirus bundibugyoense;旧称本迪布焦型埃博拉病毒)

  • 雷斯顿型正埃博拉病毒(orthoebolavirus restonense;旧称雷斯顿型埃博拉病毒)

  • 邦巴利型正埃博拉病毒(orthoebolavirus bombaliense;旧称邦巴利型埃博拉病毒)

病毒名称保持不变且符合正确的分类。

更新原始来源

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 在过去 21 日内暴露于正埃博拉病毒
  • 发热
  • 肌痛
  • 结膜充血

其他诊断因素

  • 疲劳
  • 厌食
  • 腹泻
  • 呕吐
  • 剧烈头痛
  • 腹痛或烧心
  • 咳嗽、呼吸困难、胸痛
  • 咽痛
  • 虚脱
  • 呼吸急促
  • 斑丘疹
  • 出血
  • 肝肿大
  • 淋巴结肿大
  • 呃逆
  • 心动过速
  • 低血压
  • 神经系统体征

危险因素

  • 先前 21 天在流行区生活或工作或者从流行区归来
  • 接触感染者的体液
  • 职业暴露
  • 屠宰感染(或潜在感染)动物或摄入此类动物的肉
  • 生物恐怖主义

诊断性检查

首要检查

  • 逆转录聚合酶链反应 (RT-PCR)
  • 疟疾检查

需考虑的检查

  • 血清电解质水平
  • 血清肌酐和尿素
  • 血乳酸
  • 动脉血气分析 (ABG)
  • 全血细胞计数(FBC)
  • 凝血功能检查
  • 尿液分析
  • 肝功能检查 (LFT)
  • 血清淀粉酶水平
  • 血糖
  • 血培养
  • 抗原捕获酶联免疫吸附测定 (ELISA)
  • IgM 和 IgG 抗体
  • 胸部 X 线检查

新兴检查

  • 快速诊断化验

治疗流程

急症处理

撰稿人

作者

Catherine F. Houlihan, MSc, MB ChB, MRCP, DTM&H

Clinical Lecturer

University College London

Honorary Clinical Lecturer

London School of Hygiene and Tropical Medicine

London

UK

利益声明

CFH has been on a scientific advisory board for Valneva regarding Chikungunya vaccines.

Manuel Fenech, MD, MRCP, DTM&H

Specialist Trainee in Infectious Diseases

Royal Liverpool University Hospital

Liverpool

UK

利益声明

MF declares that he has no competing interests.

Tom E. Fletcher, MBE, MBChB, MRCP, DTM&H

Wellcome Trust/MoD Research Fellow

Liverpool School of Tropical Medicine

Liverpool

UK

利益声明

TEF is an author of a number of references cited in this monograph. TEF is a consultant/expert panel member to the World Health Organization, and is funded by the UK Surgeon General and the Wellcome Trust. TEF has received research grants from the Medical Research Council and the UK Public Health Rapid Support Team (UK-PHRST).

鸣谢

Dr Catherine F. Houlihan, Dr Manuel Fenech, and Dr Tom E. Fletcher would like to thank Dr Nicholas J. Beeching, a previous contributor to this topic, and Dr Colin Brown (Infectious Disease Lead, Kings Sierra Leone Partnership) for his helpful comments and insights.

利益声明

NJB was partially supported by the National Institute of Health Research Health Protection Unit in Emerging and Zoonotic Infections at the University of Liverpool and Public Health England. NJB is an author of references cited in this topic. CB declares that he has no competing interests.

同行评议者

William A. Petri, Jr, MD, PhD, FACP

Wade Hampton Frost Professor of Epidemiology

Professor of Medicine, Microbiology, and Pathology

Chief

Division of Infectious Diseases and International Health

University of Virginia

Charlottesville

VA

利益声明

WAP declares that he has no competing interests.

Luis Ostrosky-Zeichner, MD, FACP, FIDSA, FSHEA

Professor of Medicine and Epidemiology

UT Health Medical School

Medical Director of Epidemiology

Memorial Hermann Texas Medical Center

Houston

TX

利益声明

LO-Z declares that he has no competing interests.

Stephen Mepham, MRCP (UK), FRCPATH, DTM&H, MD

Consultant in Microbiology and Infectious Diseases

Royal Free London NHS Foundation Trust

London

UK

利益声明

SM declares that he has no competing interests.

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