Resumen
Definición
Anamnesis y examen
Principales factores de diagnóstico
- possível exposição ao sarampo
- indivíduos não vacinados/com vacinação incompleta
- febre
- tosse
- coriza
- conjuntivite
- Manchas de Koplik
- exantema maculopapular
Factores de riesgo
- exposição ao vírus do sarampo
- ausência de imunização anterior contra o sarampo
- falha na resposta vacinal contra o sarampo
Pruebas diagnósticas
Primeras pruebas diagnósticas para solicitar
- sorologia de imunoglobulina M (IgM) e de imunoglobulina G (IgG) específica ao sarampo (ELISA)
- saliva
Pruebas diagnósticas que deben considerarse
- sorologia das fases aguda e convalescente de IgG específica para sarampo
- detecção de ácido ribonucleico (RNA) do sarampo por reação em cadeia da polimerase
- detecção de antígeno mediante anticorpo fluorescente ou técnicas de reação em cadeia da polimerase
- isolamento do vírus no sistema de cultura de tecido
Algoritmo de tratamiento
Colaboradores
Autores
Elizabeth Barnett, MD
Professor of Pediatrics
Boston University School of Medicine
Boston Medical Center
Boston
MA
Divulgaciones
EB receives clinical trial funds from Pfizer (COVID, PCV20, and RSV vaccines) and GSK (MMRV vaccine). She receives royalties from Elsevier (Immigrant Medicine), AAP (Nelson's antimicrobial therapy), and honoraria from AAP (Red Book). She participated in an Advisory Board (Sobi, RSV).
Revisores por pares
Sharon Nachman, MD
Professor of Pediatrics
Division Chief Pediatric Infectious Disease
State University of New York at Stony Brook
Stony Brook
NY
Divulgaciones
SN declares that she has no competing interests.
Linda Nield, MD, FAAP
Professor of Pediatrics
West Virginia University School of Medicine
Morgantown
WV
Divulgaciones
LN is an author of a reference cited in this topic.
Aisha Sethi, MD
Assistant Professor of Medicine
Associate Residency Program Director
University of Chicago
Chicago
IL
Divulgaciones
AS declares that she has no competing interests.
Agradecimiento de los revisores por pares
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Divulgaciones
Las afiliaciones y divulgaciones de los revisores por pares se refieren al momento de la revisión.
Referencias
Artículos principales
McLean HQ, Fiebelkorn AP, Temte JL, et al; Centers for Disease Control and Prevention. Prevention of measles, rubella, congenital rubella syndrome, and mumps, 2013: summary recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2013 Jun 14;62(RR-04):1-34.Texto completo Resumen
UK Health Security Agency. Measles: the green book, chapter 21. Dec 2019 [internet publication].Texto completo
Centers for Disease Control and Prevention. Child and adolescent immunization schedule: recommendations for ages 18 years or younger, United States, 2025. Nov 2024 [internet publication].Texto completo
Centers for Disease Control and Prevention. Adult immunization schedule: recommendations for ages 19 years or older, United States, 2025. Nov 2024 [internet publication].Texto completo
Committee on Infectious Diseases, American Academy of Pediatrics. Measles. In: Kimberlin DW, Banerjee R, Barnett ED, et al, eds. Red Book: 2024-2027 Report of the Committee on Infectious Diseases. 33rd ed. Itasca, IL: American Academy of Pediatrics; 2024.Texto completo
Artículos de referencia
Una lista completa de las fuentes a las que se hace referencia en este tema está disponible aquí.
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