COPD 患者经常漏报急性加重的症状。[162]Jones PW, Lamarca R, Chuecos F, et al. Characterisation and impact of reported and unreported exacerbations: results from ATTAIN. Eur Respir J. 2014 Nov;44(5):1156-65.
https://erj.ersjournals.com/content/44/5/1156.long
http://www.ncbi.nlm.nih.gov/pubmed/25234803?tool=bestpractice.com
在患者就诊时，常规询问患者症状加重情况；确保患者能区分意料之中的日常症状变化与 COPD 加重的前驱症状。建议患者在出现发热、呼吸状态恶化超过正常日常变化和/或脓痰显著增多时寻求临床建议。
对于任何正在使用全身皮质类固醇治疗 COPD 急性加重的糖尿病患者，应建议他们密切监测自己的血糖水平，如果该水平超过目标范围，应寻求医疗建议。[163]Joint British Diabetes Societies for Inpatient Care. Management of hyperglycaemia and steroid (glucocorticoid) therapy. October 2014 [internet publication].
https://www.diabetes.org.uk/resources-s3/2017-09/JBDS%20management%20of%20hyperglycaemia%20and%20steriod%20therapy_0.pdf
对于任何接受抗生素治疗加重的患者：[95]National Institute for Health and Care Excellence. Chronic obstructive pulmonary disease (acute exacerbation): antimicrobial prescribing. December 2018 [internet publication].
https://www.nice.org.uk/guidance/ng114
