Meningococcal disease

SINAIS / SINTOMAS

Purpura fulminans is more characteristic in meningococcemia than in sepsis caused by other bacterial pathogens.

SINAIS / SINTOMAS

Purpura fulminans is more characteristic in meningococcemia than in sepsis caused by other bacterial pathogens.

SINAIS / SINTOMAS

Purpura fulminans is more characteristic in meningococcemia than in sepsis caused by other bacterial pathogens.

SINAIS / SINTOMAS

Residence in or travel history to an area with local transmission of COVID-19, or close contact with a suspected or confirmed case in the 14 days prior to symptom onset.

May be difficult to distinguish clinically from bacterial pneumonia. In addition to fever, cough, and dyspnea, other common presenting symptoms include sore throat, myalgia, fatigue, and altered sense of taste and/or smell.

Patients with respiratory distress may have tachycardia, tachypnea, or cyanosis accompanying hypoxia.

SINAIS / SINTOMAS

Pharyngeal erythema and, frequently, tonsillar exudates and tender cervical adenopathy. Although the onset is abrupt, the infection does not progress rapidly.

SINAIS / SINTOMAS

Typically presents with septic arthritis, tenosynovitis, and tender pustular skin lesions. Infections are most common in women and often begin within a week of the start of a menstrual period. Unlike meningococcemia, disseminated gonococcemia rarely progresses rapidly.

SINAIS / SINTOMAS

The disease course may be bimodal, with fever, meningitis, and a rash, which may be hemorrhagic, developing several days after improvement in initial symptoms. Hepatitis, jaundice, interstitial nephritis, and myocarditis are common in severe Leptospira infections but are rare in meningococcal infections.

SINAIS / SINTOMAS

Typically progresses more slowly than meningococcemia. The rash of Rocky Mountain spotted fever (RMSF) begins on the distal extremities and spreads proximally.

ПРИЗНАКИ / СИМПТОМЫ

Typically progresses more slowly than meningococcemia. Rash is uncommon, especially in adults.

ПРИЗНАКИ / СИМПТОМЫ

Typically progresses more slowly than meningococcemia. Rash is uncommon.

ПРИЗНАКИ / СИМПТОМЫ

Bacterial endocarditis infrequently progresses rapidly to septic shock or meningitis, and patients typically have a longer duration of fever prior to presentation. A new or changed heart murmur, septic emboli, immunologic sequelae such as glomerulonephritis, and splenomegaly are common in endocarditis and not observed with meningococcal infections.

ПРИЗНАКИ / СИМПТОМЫ

Nonpurulent conjunctivitis, pharyngitis, and erythroderma or a scarlatiniform rash that later desquamates are characteristic of toxic shock syndrome (TSS). Gastrointestinal complaints, hepatitis, severe muscle pain, elevated serum creatine kinase (CK), and renal abnormalities are more common in TSS than in meningococcal infections. Focal pyogenic infections may be observed in patients with TSS, particularly those caused by staphylococci.

ПРИЗНАКИ / СИМПТОМЫ

Rashes are most commonly erythematous and maculopapular but may be petechial. Stomatitis is characteristic of group A Coxsackie viruses.

ПРИЗНАКИ / СИМПТОМЫ

Cervical and generalized adenopathy, hepatosplenomegaly, and hepatitis are common. Severe illness is rare.

ПРИЗНАКИ / СИМПТОМЫ

Beyond the neonatal period, a hemorrhagic rash is unusual. Pharyngitis, cervical adenopathy, and hepatosplenomegaly are common. Severe illness, with pneumonitis, chorioretinitis, enteritis, hepatitis, meningoencephalitis, coagulopathy, and pancytopenia, occurs in neonates and immunocompromised patients.

ПРИЗНАКИ / СИМПТОМЫ

Respiratory symptoms, including pharyngitis, rhinitis, and cough, are prominent. Rash is uncommon, but petechiae may be present.

ПРИЗНАКИ / СИМПТОМЫ

There may be an ongoing community outbreak. Respiratory symptoms, including pharyngitis, rhinitis, and cough, are prominent. Rash is uncommon, but petechiae may be present.

ПРИЗНАКИ / СИМПТОМЫ

There may be an ongoing community outbreak. Respiratory symptoms, including pharyngitis, rhinitis, and cough, are prominent. Rash is uncommon, but petechiae may be present.

ПРИЗНАКИ / СИМПТОМЫ

There may be a history of travel to an endemic area 1 to 12 days prior to symptoms. Hepatitis and jaundice are more common in viral hemorrhagic fevers than in meningococcal infections.

SIGNS / SYMPTOMS

Typically, lack of fever or other signs of infection.

SIGNS / SYMPTOMS

Palpable purpuric rash, most commonly on the lower extremities; abdominal pain and vomiting; joint pain; and swelling and edema of the distal extremities, scalp, and scrotum.

SIGNS / SYMPTOMS

Fever less common than in meningococcemia.

SIGNS / SYMPTOMS

Fever less common than in meningococcemia but may be present in patients with secondary infections. Most patients have physical and laboratory findings suggestive of their primary disorder, such as bleeding from mucosal sites and pancytopenia.

SINAIS / SINTOMAS

Most patients have physical and laboratory findings suggestive of their primary disorder, such as weight loss, splenomegaly, adenopathy, and pancytopenia.