Case history #1
A 61-year-old man presents to hospital on 3 March 2020 with fever, cough, and difficulty breathing. He also reports feeling very tired and unwell. He has a history of congestive heart failure, which is controlled with medication. On examination, his pulse is 120 bpm and his temperature is 38.7°C (101.6°F). Chest x-ray shows bilateral lung infiltrates. He is admitted to hospital in an isolation room and is started on oxygen, intravenous fluids, empirical antibiotics, and paracetamol. Later that day, he tests positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on real-time reverse transcriptase polymerase chain reaction testing. The patient develops respiratory distress 7 days after admission and is started on mechanical ventilation.
Case history #2
A 30-year-old man presents to his general practitioner on 14 January 2020 with a bad cough. He has had the cough for 4 days and now feels a little short of breath. He also has a headache and reports that his muscles ache. On examimation, his pulse is 100 bpm and his temperature is 38.5°C (101.3°F). The patient reports that he returned from a business trip in mainland China 6 days ago.
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