All patients should be well educated about the disease course and symptoms of exacerbation or decompensation. Their expectation of the disease, treatment, and prognosis should be realistic. It is important to remember that no medicine has been shown to modify the long-term decline in lung function, and the primary goal of pharmacotherapy is to control symptoms and prevent complications.
Regular medical follow-up is necessary to optimize the treatment. If there is any worsening of symptoms, immediate medical attention is required.
Self-management interventions
Action plans for acute exacerbations of COPD are associated with improvements in health-related quality of life and fewer admissions to the hospital for respiratory problems.[146]Lenferink A, Brusse-Keizer M, van der Valk PD, et al. Self-management interventions including action plans for exacerbations versus usual care in patients with chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2017 Aug 4;(8):CD011682.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD011682.pub2/full
http://www.ncbi.nlm.nih.gov/pubmed/28777450?tool=bestpractice.com
Self-management plans should include personalized advice on:[1]Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: 2024 report. 2024 [internet publication].
https://goldcopd.org/2024-gold-report
Breathlessness and stress management techniques
Energy conservation
Avoiding aggravating factors
How to monitor symptoms
How to manage worsening symptoms
Contact information to use in the event of an exacerbation
Studies have found a beneficial effect of cognitive behavioral therapy (CBT) on outcomes including symptoms of depression and anxiety, quality of life, and frequency of emergency department visits.[150]Pollok J, van Agteren JE, Esterman AJ, et al. Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2019 Mar 6;(3):CD012347.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD012347.pub2/full
http://www.ncbi.nlm.nih.gov/pubmed/30838649?tool=bestpractice.com
[151]Ma RC, Yin YY, Wang YQ, et al. Effectiveness of cognitive behavioural therapy for chronic obstructive pulmonary disease patients: a systematic review and meta-analysis. Complement Ther Clin Pract. 2020 Feb;38:101071.
http://www.ncbi.nlm.nih.gov/pubmed/31743870?tool=bestpractice.com
[152]Williams MT, Johnston KN, Paquet C. Cognitive behavioral therapy for people with chronic obstructive pulmonary disease: rapid review. Int J Chron Obstruct Pulmon Dis. 2020 Apr 23;15:903-19.
https://www.dovepress.com/cognitive-behavioral-therapy-for-people-with-chronic-obstructive-pulmo-peer-reviewed-fulltext-article-COPD
http://www.ncbi.nlm.nih.gov/pubmed/32425516?tool=bestpractice.com
Patients should be encouraged to:[153]Jolly K, Sidhu MS, Hewitt CA, et al. Self management of patients with mild COPD in primary care: randomised controlled trial. BMJ. 2018 Jun 13;361:k2241.
https://www.bmj.com/content/361/bmj.k2241.long
http://www.ncbi.nlm.nih.gov/pubmed/29899047?tool=bestpractice.com
[154]Long H, Howells K, Peters S, et al. Does health coaching improve health-related quality of life and reduce hospital admissions in people with chronic obstructive pulmonary disease? A systematic review and meta-analysis. Br J Health Psychol. 2019 Sep;24(3):515-46.
https://bpspsychub.onlinelibrary.wiley.com/doi/10.1111/bjhp.12366
http://www.ncbi.nlm.nih.gov/pubmed/31033121?tool=bestpractice.com
Quit active or passive smoking
Avoid environmental exposure to toxic fumes
Stay as healthy and active as possible
Subscribe to health coaching (where available)
See Smoking cessation (Patient discussions).
Recommend physical activity
Systematic reviews and meta-analyses report that:[164]Lahham A, McDonald CF, Holland AE. Exercise training alone or with the addition of activity counseling improves physical activity levels in COPD: a systematic review and meta-analysis of randomized controlled trials. Int J Chron Obstruct Pulmon Dis. 2016 Dec 8;11:3121-36.
https://www.dovepress.com/exercise-training-alone-or-with-the-addition-of-activity-counseling-im-peer-reviewed-fulltext-article-COPD
http://www.ncbi.nlm.nih.gov/pubmed/27994451?tool=bestpractice.com
[170]Cramer H, Haller H, Klose P, et al. The risks and benefits of yoga for patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis. Clin Rehabil. 2019 Dec;33(12):1847-62.
http://www.ncbi.nlm.nih.gov/pubmed/31353959?tool=bestpractice.com
[171]Tong H, Liu Y, Zhu Y, et al. The therapeutic effects of qigong in patients with chronic obstructive pulmonary disease in the stable stage: a meta-analysis. BMC Complement Altern Med. 2019 Sep 4;19(1):239.
https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-019-2639-9
http://www.ncbi.nlm.nih.gov/pubmed/31484521?tool=bestpractice.com
[172]Lu Y, Li P, Li N, et al. Effects of home-based breathing exercises in subjects with COPD. Respir Care. 2020 Mar;65(3):377-87.
https://rc.rcjournal.com/content/65/3/377
http://www.ncbi.nlm.nih.gov/pubmed/31719191?tool=bestpractice.com
[173]Liu X, Fu C, Hu W, et al. The effect of Tai Chi on the pulmonary rehabilitation of chronic obstructive pulmonary disease: a systematic review and meta-analysis. Ann Palliat Med. 2021 Apr;10(4):3763-82.
https://apm.amegroups.org/article/view/67333/html
http://www.ncbi.nlm.nih.gov/pubmed/33894710?tool=bestpractice.com
[271]Iepsen UW, Jørgensen KJ, Ringbæk T, et al. A combination of resistance and endurance training increases leg muscle strength in COPD: an evidence-based recommendation based on systematic review with meta-analyses. Chron Respir Dis. 2015 May;12(2):132-45.
https://journals.sagepub.com/doi/10.1177/1479972315575318
http://www.ncbi.nlm.nih.gov/pubmed/25767138?tool=bestpractice.com
Exercise training on its own can improve physical activity in COPD; greater improvements can be made with the addition of physical activity counseling
Combined aerobic exercise and strength training is more effective than aerobic exercise alone in increasing leg muscle strength
Exercise capacity and pulmonary function can be improved with yoga, Qigong, Tai Chi, and other home-based breathing exercises.
One Cochrane review concluded that there is limited evidence for improvement in physical activity with physical activity counseling, exercise training, and pharmacologic management of COPD.[169]Burge AT, Cox NS, Abramson MJ, et al. Interventions for promoting physical activity in people with chronic obstructive pulmonary disease (COPD). Cochrane Database Syst Rev. 2020 Apr 16;(4):CD012626.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD012626.pub2/full
http://www.ncbi.nlm.nih.gov/pubmed/32297320?tool=bestpractice.com
[ ]
Which interventions lead to increased regular physical activity for people with chronic obstructive pulmonary disease (COPD)?/cca.html?targetUrl=https://www.cochranelibrary.com/cca/doi/10.1002/cca.3155/fullShow me the answer Interventions included in the review assessed in the review had primarily been assessed in single studies. The optimal timing, components, duration, and models for improving physical activity remain unclear.
Consider inhaler device technique
Ask patients to bring their inhalers to clinic to facilitate a review of inhaler use.[1]Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: 2024 report. 2024 [internet publication].
https://goldcopd.org/2024-gold-report
[158]Price D, Keininger DL, Viswanad B, et al. Factors associated with appropriate inhaler use in patients with COPD - lessons from the REAL survey. Int J Chron Obstruct Pulmon Dis. 2018 Feb 26;13:695-702. [Erratum in: Int J Chron Obstruct Pulmon Dis. 2018 Jul 25;13:2253-4.]
https://www.dovepress.com/factors-associated-with-appropriate-inhaler-use-in-patients-with-copd--peer-reviewed-fulltext-article-COPD
http://www.ncbi.nlm.nih.gov/pubmed/29520137?tool=bestpractice.com
[159]Maricoto T, Monteiro L, Gama JMR, et al. Inhaler technique education and exacerbation risk in older adults with asthma or chronic obstructive pulmonary disease: a meta-analysis. J Am Geriatr Soc. 2019 Jan;67(1):57-66.
http://www.ncbi.nlm.nih.gov/pubmed/30291745?tool=bestpractice.com
[160]Jia X, Zhou S, Luo D, et al. Effect of pharmacist-led interventions on medication adherence and inhalation technique in adult patients with asthma or COPD: a systematic review and meta-analysis. J Clin Pharm Ther. 2020 Oct;45(5):904-17.
https://onlinelibrary.wiley.com/doi/10.1111/jcpt.13126
http://www.ncbi.nlm.nih.gov/pubmed/32107837?tool=bestpractice.com
[161]Willard-Grace R, Chirinos C, Wolf J, et al. Lay health coaching to increase appropriate inhaler use in COPD: a randomized controlled trial. Ann Fam Med. 2020 Jan;18(1):5-14.
https://www.annfammed.org/content/18/1/5
http://www.ncbi.nlm.nih.gov/pubmed/31937527?tool=bestpractice.com
Demonstrate inhaler use and review technique at subsequent appointments; using a placebo device may be most effective for teaching inhaler technique to adults ages ≥65 years,
Pharmacist-led interventions and lay health coaching can improve inhaler technique and adherence.
Preferred inhaler device attributes (e.g., small size, rapid onset of symptom relief) have been reported in patient preference studies.[162]Navaie M, Dembek C, Cho-Reyes S, et al. Inhaler device feature preferences among patients with obstructive lung diseases: a systematic review and meta-analysis. Medicine (Baltimore). 2020 Jun 19;99(25):e20718.
https://journals.lww.com/md-journal/fulltext/2020/06190/inhaler_device_feature_preferences_among_patients.56.aspx
http://www.ncbi.nlm.nih.gov/pubmed/32569208?tool=bestpractice.com
[163]Tervonen T, Hawken N, Hanania NA, et al. Maintenance inhaler therapy preferences of patients with asthma or chronic obstructive pulmonary disease: a discrete choice experiment. Thorax. 2020 Sep;75(9):735-43.
https://thorax.bmj.com/content/75/9/735
http://www.ncbi.nlm.nih.gov/pubmed/32631932?tool=bestpractice.com
The majority of patients make at least one error in using their inhaler, and incorrect inhaler use is associated with worse disease control.[155]Cho-Reyes S, Celli BR, Dembek C, et al. Inhalation technique errors with metered-dose inhalers among patients with obstructive lung diseases: a systematic review and meta-analysis of US Studies. Chronic Obstr Pulm Dis. 2019 Jul 24;6(3):267-80.
https://journal.copdfoundation.org/jcopdf/id/1241/Inhalation-Technique-Errors-with-Metered-Dose-Inhalers-Among-Patients-with-Obstructive-Lung-Diseases-A-Systematic-Review-and-Meta-Analysis-of-US-Studies
http://www.ncbi.nlm.nih.gov/pubmed/31342732?tool=bestpractice.com
[156]Melani AS, Bonavia M, Cilenti V, et al. Inhaler mishandling remains common in real life and is associated with reduced disease control. Respir Med. 2011 Jun;105(6):930-8.
https://www.resmedjournal.com/article/S0954-6111(11)00009-6/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/21367593?tool=bestpractice.com
Poor technique is more likely when patients are using multiple devices or have never received inhaler technique training.[157]Rootmensen GN, van Keimpema AR, Jansen HM, et al. Predictors of incorrect inhalation technique in patients with asthma or COPD: a study using a validated videotaped scoring method. J Aerosol Med Pulm Drug Deliv. 2010 Oct;23(5):323-8.
http://www.ncbi.nlm.nih.gov/pubmed/20804428?tool=bestpractice.com
Metered dose inhalerA principal pharmacist shows a patient how to use a metered dose inhaler and discusses ways of improving inhaler technique.
Metered dose inhaler plus spacerA principal pharmacist shows a patient how to use a metered dose inhaler plus a spacer and discusses ways of improving inhaler technique.
Dry powder inhalersA principal pharmacist shows a patient how to use dry powder devices and discusses ways of improving inhaler technique.
Soft mist inhalerA principal pharmacist shows a patient how to use a soft mist inhaler and discusses ways of improving inhaler technique.
Dietary advice and oral supplements
Have been found to improve body weight, quality of life, respiratory muscle strength and 6-minute walk distance.[174]Collins PF, Elia M, Stratton RJ. Nutritional support and functional capacity in chronic obstructive pulmonary disease: a systematic review and meta-analysis. Respirology. 2013 May;18(4):616-29.
https://onlinelibrary.wiley.com/doi/10.1111/resp.12070
http://www.ncbi.nlm.nih.gov/pubmed/23432923?tool=bestpractice.com
[175]Ferreira IM, Brooks D, White J, et al. Nutritional supplementation for stable chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2012 Dec 12;(12):CD000998.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000998.pub3/full
http://www.ncbi.nlm.nih.gov/pubmed/23235577?tool=bestpractice.com
Nutritional support has not been consistently found to improve lung function.[175]Ferreira IM, Brooks D, White J, et al. Nutritional supplementation for stable chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2012 Dec 12;(12):CD000998.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000998.pub3/full
http://www.ncbi.nlm.nih.gov/pubmed/23235577?tool=bestpractice.com
Preparing for air travel
Optimize the patient's condition prior to air travel and assess their need for inflight oxygen. Advise patients to:[206]British Thoracic Society. Air travel. Mar 2022 [internet publication].
https://www.brit-thoracic.org.uk/quality-improvement/clinical-statements/air-travel
Inquire about venous thromboembolism prophylaxis, especially before long flights
Carry all medications and spacer devices in their hand luggage
Have any emergency medications immediately accessible during the flight
Consider increased oxygen flow during air travel (if receiving continuous oxygen therapy)