糖尿病酮症酸中毒（diabetic ketoacidosis, DKA）的特点是生化检查同时出现高血糖（或糖尿病史）、酮血症和代谢性酸中毒三联征，并且症状发作迅速。
英国儿科内分泌学和糖尿病学会（British Society for Paediatric Endocrinology and Diabetes）发布了儿童 DKA 管理指南。
- 药物（例如皮质类固醇、噻嗪类药物、喷他脒、拟交感神经药、第二代抗精神病药物、可卡因、免疫检查点抑制剂或 SGLT-2 抑制剂）
- 胸部 X 线检查
初始收缩压 <90 mmHg
初始收缩压 ≥90 mmHg
Gerry Rayman, MD, FRCP
Consultant Physician and Head of Service
Diabetes and Endocrine Centre and the Diabetes Research Unit
Ipswich Hospitals NHS Trust
GR is Lead and Innovator of the National Inpatient Diabetes Audit; and Joint Clinical Lead of the Diabetes, Getting It Right First Time programme.
GR has been paid for advisory board meetings with the following companies: Sanofi Aventis, Abbott Diabetes UK, Lilly Diabetes, and Bayer. GR has received lecture fees from Sanofi Aventis, Abbott Diabetes UK, Lilly Diabetes, Novo Nordisk, and Napp Pharmaceuticals Ltd.
BMJ Best Practice would like to gratefully acknowledge the previous team of expert contributors, whose work has been retained in parts of the content:
Aidar R. Gosmanov, MD, PhD, FACE
Associate Professor of Medicine
Division of Endocrinology
Albany Medical College
Chief, Endocrinology Section
Laleh Razavi Nematollahi, MD
Assistant Professor of Medicine
Case Western Reserve University
ARG and LRN declare that they have no competing interests.
Edward Jude, MD, MRCP
Consultant Diabetologist and Endocrinologist
Tameside and Glossop Integrated Care NHS Foundation Trust
Honorary Professor, University of Manchester
Honorary Professor, Manchester Metropolitan University Manchester
EJ declares that he has no competing interests.
Ketan Dhatariya, MBBS, MSc, MD, MS, FRCP, PhD
Honorary Professor of Medicine
Norwich Medical School, University of East Anglia
Consultant Diabetes & Endocrinology
Norfolk and Norwich University Hospitals NHS Foundation Trust
KD is the chair of the Joint British Diabetes Societies for Inpatient Care. KD has received honoraria from Diabetes Professional Care to speak at its annual meeting about these guidelines. No other reimbursement has been received from commercial organisations with respect to these guidelines. KD has helped to develop educational materials on this subject for the European Association for the Study of Diabetes, but did not receive any reimbursement. For other work as the chair of JBDS, KD has received honoraria from Lilly for developing educational material.
Section Editor, BMJ Best Practice
AS declares that she has no competing interests.
Head of Research and Development, BMJ
LD declares that she has no competing interests.
Head of Editorial, BMJ Best Practice
AE declares that she has no competing interests.
Lead Section Editor, BMJ Best Practice
RW declares that she has no competing interests.
Comorbidities Editor, BMJ Best Practice
JC declares that she has no competing interests.
Drug Editor, BMJ Best Practice
AM declares that he has no competing interests.
- 高渗性高血糖状态 (HHS)
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