Hantavirus cardiopulmonary syndrome

References

Key articles

Jonsson CB, Hooper J, Mertz G. Treatment of hantavirus pulmonary syndrome. Antiviral Res. 2008 Apr;78(1):162-9.Full text  Abstract

Mertz GJ, Hjelle B, Crowley M, et al. Diagnosis and treatment of new world hantavirus infections. Curr Opin Infect Dis. 2006 Oct;19(5):437-42. Abstract

Chang B, Crowley M, Campen M, et al. Hantavirus cardiopulmonary syndrome. Semin Respir Crit Care Med. 2007 Apr;28(2):193-200. Abstract

Centers for Disease Control and Prevention. Hantavirus pulmonary syndrome (HPS) 2015 case definition. 2015 [internet publication].Full text

Centers for Disease Control and Prevention. General hantavirus technical/clinical information: clinical manifestation. August 2012 [internet publication].Full text

Reference articles

1. Vapalahti O, Mustonen J, Lundkvist A, et al. Hantavirus infections in Europe. Lancet Infect Dis. 2003 Oct;3(10):653-61. Abstract

2. Miller MJ. Viral taxonomy. Clin Infect Dis. 1999 Oct;29(4):731-3.Full text  Abstract

3. McCaughey C, Hart CA. Hantaviruses. J Med Microbiol. 2000 Jul;49(7):587-99.Full text  Abstract

4. Figueiredo LT, Souza WM, Ferrés M, et al. Hantaviruses and cardiopulmonary syndrome in South America. Virus Res. 2014 Jul 17;187:43-54. Abstract

5. Peters CJ, Khan AS. Hantavirus pulmonary syndrome: the new American hemorrhagic fever. Clin Infect Dis. 2002 May 1;34(9):1224-31.Full text  Abstract

6. Hjelle B, Goade D, Torrez-Martinez N, et al. Hantavirus pulmonary syndrome, renal insufficiency and myositis associated with infection by Bayou hantavirus. Clin Infect Dis. 1996 Sep;23(3):495-500. Abstract

7. Khan AS, Gaviria M, Rollin PE, et al. Hantavirus pulmonary syndrome in Florida: association with the newly identified Black Creek Canal virus. Am J Med. 1996 Jan;100(1):46-8. Abstract

8. Centers for Disease Control and Prevention. Reported cases of hantavirus disease: hantavirus infection in the United States. 2022 May [internet publication].Full text

9. Centers for Disease Control and Prevention. Multi-state outbreak of Seoul virus. Apr 2017 [internet publication].Full text

10. European Centre for Disease Prevention and Control. Hantavirus infection - annual epidemiological report for 2019. 2021 April European Centre for Disease Prevention and Control. Chikungunya virus disease - annual epidemiological report for 2017. April 2019 [internet publication].Full text

11. Abbott KD, Ksiazek TG, Mills JN. Long-term hantavirus persistence in rodent populations in central Arizona. Emerg Infect Dis. 1999 Jan-Feb;5(1):102-12.Full text  Abstract

12. Butler JC, Peters CJ. Hantaviruses and hantavirus pulmonary syndrome. Clin Infect Dis. 1994 Sep;19(3):387-94;quiz 395. Abstract

13. Núñez JJ, Fritz CL, Knust B, et al. Hantavirus infections among overnight visitors to Yosemite National Park, California, USA, 2012. Emerg Infect Dis. 2014 Mar;20(3):386-93.Full text  Abstract

14. World Health Organization. Hantavirus pulmonary syndrome - Argentine Republic. Jan 2019 [internet publication].Full text

15. Centers for Disease Control and Prevention. Morbidity and Mortality Weekly Report​. Notes from the field: contact tracing investigation after first case of andes virus in the United States — Delaware, February 2018. Oct 2018 [internet publication].Full text

16. Calisher CH, Mills JN, Root JJ, et al. Hantaviruses: etiologic agents of rare but potentially life-threatening zoonotic diseases. J Am Vet Med Assoc. 2003 Jan 15;222(2):163-6. Abstract

17. Howard MJ, Doyle TJ, Koster FT, et al. Hantavirus pulmonary syndrome in pregnancy. Clin Infect Dis. 1999 Dec;29(6):1538-44.Full text  Abstract

18. Public Health England. Andes hantavirus: epidemiology, outbreaks and guidance. 2021 May [internet publication].Full text

19. Martinez VP, Bellomo C, San Juan J, et al. Person-to-person transmission of Andes virus. Emerg Infect Dis. 2005 Dec;11(12):1848-53.Full text  Abstract

20. Martinez-Valdebenito C, Calvo M, Vial C, et al. Person-to-person household and nosocomial transmission of andes hantavirus, Southern Chile, 2011. Emerg Infect Dis. 2014 Oct;20(10):1629-36.Full text  Abstract

21. Toledo J, Haby MM, Reveiz L, et al. Evidence for human-to-human transmission of hantavirus: a systematic review. J Infect Dis. 2022 Oct 17;226(8):1362-71.Full text  Abstract

22. Ferres M, Vial P, Marco C, et al. Prospective evaluation of household contacts of persons with hantavirus cardiopulmonary syndrome in Chile. J Infect Dis. 2007 Jun 1;195(11):1563-71.Full text  Abstract

23. Godoy P, Marsac D, Stefas E, et al. Andes virus antigens are shed in urine of patients with acute hantavirus cardiopulmonary syndrome. J Virol. 2009 May;83(10):5046-55.Full text  Abstract

24. Castillo C, Villagra E, Sanhueza L, et al. Prevalence of antibodies to hantavirus among family and health care worker contacts of persons with hantavirus cardiopulmonary syndrome: lack of evidence for nosocomial transmission of Andes virus to health care workers in Chile. Am J Trop Med Hyg. 2004 Mar;70(3):302-4.Full text  Abstract

25. Ferrer JF, Jonsson CB, Esteban E, et al. High prevalence of hantavirus infection in Indian communities of the Paraguayan and Argentinean Gran Chaco. Am J Trop Med Hyg. 1998 Sep;59(3):438-44.Full text  Abstract

26. Campos GM, Moro de Sousa RL, Badra SJ, et al. Serological survey of hantavirus in Jardinopolis County, Brazil. J Med Virol. 2003 Nov;71(3):417-22. Abstract

27. Muñoz-Zanzi C, Saavedra F, Otth C, et al. Serological evidence of hantavirus infection in apparently healthy people from rural and slum communities in southern Chile. Viruses. 2015 Apr 17;7(4):2006-13.Full text  Abstract

28. Fritz CL, Young JC. Estimated incubation period for hantavirus pulmonary syndrome. Am J Trop Med Hyg. 2001 Nov;65(5):403. Abstract

29. St Jeor SC. Three-week incubation period for hantavirus infection. Pediatr Infect Dis J. 2004 Oct;23(10):974-5. Abstract

30. Borges AA, Campos GM, Moreli ML, et al. Hantavirus cardiopulmonary syndrome: immune response and pathogenesis. Microbes Infect. 2006 Jul;8(8):2324-30. Abstract

31. Bharadwaj M, Nofchissey R, Goade D, et al. Humoral immune responses in the hantavirus cardiopulmonary syndrome. J Infect Dis. 2000 Jul;182(1):43-8.Full text  Abstract

32. Green W, Feddersen R, Yousef O, et al. Tissue distribution of hantavirus antigen in naturally infected humans and deer mice. J Infect Dis. 1998 Jun;177(6):1696-700. Abstract

33. Zavasky DM, Hjelle B, Peterson MC, et al. Acute infection with Sin Nombre hantavirus without pulmonary edema. Clin Infect Dis. 1999 Sep;29(3):664-6. Abstract

34. Maes P, Clement J, Gavrilovskaya I, et al. Hantaviruses: immunology, treatment, and prevention. Viral Immunol. 2004;17(4):481-97. Abstract

35. Mori M, Rothman AL, Kurane I, et al. High levels of cytokine-producing cells in the lung tissues of patients with fatal hantavirus pulmonary syndrome. J Infect Dis. 1999 Feb;179(2):295-302.Full text  Abstract

36. Gavrilovskaya IN, Gorbunova EE, Mackow ER. Pathogenic hantaviruses direct the adherence of quiescent platelets to infected endothelial cells. J Virol. 2010 May;84(9):4832-9.Full text  Abstract

37. Steinberg BE, Goldenberg NM, Lee WL. Do viral infections mimic bacterial sepsis? The role of microvascular permeability: a review of mechanisms and methods. Antiviral Res. 2012 Jan;93(1):2-15. Abstract

38. Geimonen E, LaMonica R, Springer K, et al. Hantavirus pulmonary syndrome-associated hantaviruses contain conserved and functional ITAM signaling elements. J Virol. 2003 Jan;77(2):1638-43.Full text  Abstract

39. Borges AA, Figueiredo LT. Mechanisms of shock in hantavirus pulmonary syndrome. Curr Opin Infect Dis. 2008 Jun;21(3):293-7. Abstract

40. Saggioro FP, Rossi MA, Duarte MIS, et al. Hantavirus infection induces a typical myocarditis that may be responsible for myocardial depression and shock in hantavirus pulmonary syndrome. J Infect Dis. 2007 May 15;195(10):1541-9.Full text  Abstract

41. Raftery MJ, Lalwani P, Krautkrӓmer E, et al. β2 integrin mediates hantavirus-induced release of neutrophil extracellular traps. J Exp Med. 2014 Jun 30;211(7):1485-97.Full text  Abstract

42. Hjelle B, Glass GE. Outbreak of hantavirus infection in the Four Corners region of the United States in the wake of the 1997-1998 El Nino-southern oscillation. J Infect Dis. 2000 May;181(5):1569-73.Full text  Abstract

43. Jonsson CB, Hooper J, Mertz G. Treatment of hantavirus pulmonary syndrome. Antiviral Res. 2008 Apr;78(1):162-9.Full text  Abstract

44. Mertz GJ, Hjelle B, Crowley M, et al. Diagnosis and treatment of new world hantavirus infections. Curr Opin Infect Dis. 2006 Oct;19(5):437-42. Abstract

45. Chapman LE, Ellis BA, Koster FT, et al. Discriminators between hantavirus-infected and -uninfected persons enrolled in a trial of intravenous ribavirin for presumptive hantavirus pulmonary syndrome. Clin Infect Dis. 2002 Feb 1;34(3):293-304.Full text  Abstract

46. Chang B, Crowley M, Campen M, et al. Hantavirus cardiopulmonary syndrome. Semin Respir Crit Care Med. 2007 Apr;28(2):193-200. Abstract

47. Centers for Disease Control and Prevention. Hantavirus: diagnostics. March 2020 [internet publication].Full text

48. Figueiredo LT, Moreli ML, Borges AA, et al. Evaluation of an enzyme-linked immunosorbent assay based on Araraquara virus recombinant nucleocapsid protein. Am J Trop Med Hyg. 2009 Aug;81(2):273-6.Full text  Abstract

49. Koster F, Foucar K, Hjelle B, et al. Rapid presumptive diagnosis of hantavirus cardiopulmonary syndrome by peripheral blood smear review. Am J Clin Pathol. 2001 Nov;116(5):665-72.Full text  Abstract

50. Hjelle B, Spiropoulou CF, Torrez-Martinez N, et al. Detection of Muerto Canyon virus RNA in peripheral blood mononuclear cells from patients with hantavirus pulmonary syndrome. J Infect Dis. 1994 Oct;170(4):1013-7. Abstract

51. Xiao R, Yang S, Koster F, et al. Sin Nombre viral RNA load in patients with hantavirus cardiopulmonary syndrome. J Infect Dis. 2006 Nov 15;194(10):1403-9.Full text  Abstract

52. Ye C, Prescott J, Nofchissey R, et al. Neutralizing antibodies and Sin Nombre virus RNA after recovery from hantavirus cardiopulmonary syndrome. Emerg Infect Dis. 2004 Mar;10(3):478-82.Full text  Abstract

53. Hallin GW, Simpson SQ, Crowell RE, et al. Cardiopulmonary manifestations of hantavirus pulmonary syndrome. Crit Care Med. 1996 Feb;24(2):252-8. Abstract

54. Nolte KB, Feddersen RM, Foucar K, et al. Hantavirus pulmonary syndrome in the United States: a pathological description of a disease caused by a new agent. Hum Pathol. 1995 Jan;26(1):110-20. Abstract

55. Machado AM, Figueiredo GG, Dos Santos Junior GS, et al. Laboratory diagnosis of human hantavirus infection: novel insights and future potential. Future Virol. 2009;4:383-9.

56. Boroja M, Barrie JR, Raymond GS. Radiographic findings in 20 patients with Hantavirus pulmonary syndrome correlated with clinical outcome. AJR Am J Roentgenol. 2002 Jan;178(1):159-63.Full text  Abstract

57. Ketai LH, Kelsey CA, Jordon K, et al. Distinguishing hantavirus pulmonary syndrome from acute respiratory distress syndrome by chest radiography: are there different radiographic manifestations of increased alveolar permeability? J Thorac Imaging. 1998 Jul;13(3):172-7. Abstract

58. Centers for Disease Control and Prevention. Hantavirus pulmonary syndrome (HPS) 2015 case definition. 2015 [internet publication].Full text

59. Smith HM, Reporter R, Rood MP, et al. Prevalence study of antibody to ratborne pathogens and other agents among patients using a free clinic in downtown Los Angeles. J Infect Dis. 2002;186:1673-1676. Abstract

60. Yanagihara R. Hantavirus infection in the United States: epizootiology and epidemiology. Rev Infect Dis. 1990;12:449-457. Abstract

61. Centers for Disease Control and Prevention. CDC Yellow Book 2024 - viral hemorrhagic fevers. May 2023 [internet publication].Full text

62. Washington State Department of Health. Hantavirus pulmonary syndrome reporting and investigation guideline. Mar 2017 [internet publication].Full text

63. Crowley MR, Katz RW, Kessler R, et al. Successful treatment of adults with severe Hantavirus pulmonary syndrome with extracorporeal membrane oxygenation. Crit Care Med. 1998 Feb;26(2):409-14. [Erratum in: Crit Care Med. 1998 Apr;26(4):806.] Abstract

64. Wernly JA, Dietl CA, Tabe CE, et al. Extracorporeal membrane oxygenation support improves survival of patients with Hantavirus cardiopulmonary syndrome refractory to medical treatment. Eur J Cardiothorac Surg. 2011 Dec;40(6):1334-40.Full text  Abstract

65. Moore SA, Dietl CA, Coleman DM. Extracorporeal life support during pregnancy. J Thorac Cardiovasc Surg. 2016 Apr;151(4):1154-60. Abstract

66. Mertz GJ, Miedzinski L, Goade D, et al. Placebo controlled, double blind trial of intravenous ribavirin for the treatment of hantavirus cardiopulmonary syndrome in North America. Clin Infect Dis. 2004 Nov 1;39(9):1307-13.Full text  Abstract

67. Chapman LE, Mertz GJ, Peters CJ, et al. Intravenous ribavirin for hantavirus pulmonary syndrome: safety and tolerance during 1 year of open label experience. Ribavirin Study Group. Antivir Ther. 1999;4(4):211-9. Abstract

68. Vial PA, Valdivieso F, Ferres M, et al. High-dose intravenous methylprednisolone for hantavirus cardiopulmonary syndrome in Chile: a double-blind, randomized controlled clinical trial. Clin Infect Dis. 2013 Oct;57(7):943-51.Full text  Abstract

69. Bharadwaj M, Nofchissey R, Goade D, et al. Humoral immune responses in the hantavirus cardiopulmonary syndrome. J Infect Dis. 2000 Jul;182(1):43-8.Full text  Abstract

70. Vial PA, Valdivieso F, Calvo M et al. A non-randomized multicentre trial of human immune plasma for treatment of hantavirus cardiopulmonary syndrome caused by Andes virus. Antivir Ther. 2015;20:377-386. Abstract

71. Safronetz D, Falzarano D, Scott DP, et al. Antiviral efficacy of favipiravir against two prominent etiological agents of hantavirus pulmonary syndrome. Antimicrob Agents Chemother. 2013;57:4673-4680.Full text  Abstract

72. Gracia F, Armien B, Simpson SQ, et al. Convalescent pulmonary dysfunction following hantavirus pulmonary syndrome in Panama and the United States. Lung. 2010 Oct;188(5):387-91.Full text  Abstract

73. Pergam SA, Schmidt DW, Nofchissey RA, et al. Potential renal sequelae in survivors of hantavirus cardiopulmonary syndrome. Am J Trop Med Hyg. 2009;80:279-285. Abstract

74. Centers for Disease Control and Prevention. General hantavirus technical/clinical information: clinical manifestation. August 2012 [internet publication].Full text

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