Ebola virus infection

Centers for Disease Control and Prevention (CDC): case definition for Ebola virus disease (EVD)[84]Centers for Disease Control and Prevention. Case definition for Ebola virus disease (EVD). July 2019 [internet publication]. https://www.cdc.gov/vhf/ebola/hcp/case-definition.html

Person under investigation (PUI):

• A person who has both consistent signs or symptoms and risk factors as follows:

  • Elevated body temperature or subjective fever or symptoms, including severe headache, fatigue, muscle pain, vomiting, diarrhea, abdominal pain, or unexplained hemorrhage; AND

  • An epidemiological risk factor within the 21 days before the onset of symptoms.

  • Guidelines of when to discharge a PUI are available: CDC: considerations for discharging people under investigation (PUIs) for Ebola virus disease (EVD) external link opens in a new window

Confirmed case:

• Laboratory-confirmed diagnostic evidence of Ebola virus infection.

• CDC: case definition for Ebola virus disease (EVD) external link opens in a new window

World Health Organization: case definition for Ebola or Marburg virus disease[87]World Health Organization. Case definition recommendations for Ebola or Marburg virus diseases. August 2014 [internet publication]. https://www.who.int/csr/resources/publications/ebola/ebola-case-definition-contact-en.pdf?ua=1

The World Health Organization (WHO) has also produced a case definition:

WHO: case definition recommendations for Ebola or Marburg virus diseases external link opens in a new window