Resumen
Definición
Anamnesis y examen
Principales factores de diagnóstico
- hematuria
- edema
- hypertension
Otros factores de diagnóstico
- oliguria
- anorexia
- nausea
- malaise
- weight loss
- fever
- skin rash
- arthralgia
- hemoptysis
- abdominal pain
- sore throat
- hypervolemia
Factores de riesgo
- group A beta-hemolytic Streptococcus
- respiratory infections
- gastrointestinal infections
- hepatitis B
- hepatitis C
- infective endocarditis
- HIV
- systemic lupus erythematosus (SLE)
- systemic vasculitis
- lung cancer
- colorectal cancer
- Hodgkin lymphoma
- non-Hodgkin lymphoma
- leukemia
- thymoma
- hemolytic uremic syndrome
- drugs
Pruebas diagnósticas
Primeras pruebas diagnósticas para solicitar
- urinalysis and microscopy of urine sediment
- comprehensive metabolic profile
- estimated glomerular filtration rate (eGFR)
- complete blood count
- lipid profile
- 24-hour urine collection
- ultrasound of kidneys
Pruebas diagnósticas que deben considerarse
- spot urine protein:creatinine ratio (PCR)
- spot urine albumin:creatinine ratio (ACR)
- erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP)
- complement levels
- rheumatoid factor
- antineutrophil cytoplasmic antibody
- antiglomerular basement membrane (GBM) antibody
- antistreptolysin O antibody
- antihyaluronidase
- anti-DNase
- anti-double-stranded DNA
- antinuclear antibody
- cryoglobulins
- hepatitis C virus and hepatitis B virus serology
- HIV serology
- serum or urine protein electrophoresis
- serum free light chains
- drug screen
- kidney biopsy
- antiphospholipase A2 receptor antibodies
- computed tomographic scan of chest and abdomen
Algoritmo de tratamiento
mild disease
moderate-severe disease
rapidly progressive
Colaboradores
Autores
Nabeel Aslam, MD, FASN
Associate Professor of Medicine
Consultant Nephrologist
Mayo Clinic
Jacksonville
FL
Divulgaciones
NA declares that he has served on advisory boards for Travere Therapeutics and Chinook Therapeutics. He has received research grants from Idorsia, Novartis, and Baxter.
Agradecimientos
Dr Nabeel Aslam would like to gratefully acknowledge Dr Jeremy Levy, Dr Padmanabhan Premkumar, Dr Priyanka Sharma, and Dr Ajay Kumar, previous contributors to this topic.
Divulgaciones
JL, PP, PS, and AK declare that they have no competing interests.
Revisores por pares
Martin Schreiber, MD
Department Chairman
Nephrology and Hypertension
Cleveland Clinic Foundation
Cleveland
OH
Divulgaciones
MS declares that he has no competing interests.
Patrick Naish, MB, FRCP
Teaching Fellow
Keele University Medical School
Keele
UK
Divulgaciones
PN declares that he has no competing interests.
Richard Banks, MBBS, FRCP, MD
Consultant Nephrologist
Gloucestershire Royal Hospital
Gloucester
UK
Divulgaciones
RB declares that he has no competing interests.
Mark Thomas, BSc, MBBS, MD, FRCP
Consultant Nephrologist
University Hospitals Birmingham
Birmingham
UK
Divulgaciones
MT declares that he has no competing interests.
Referencias
Artículos principales
Kidney Disease: Improving Global Outcomes (KDIGO) Glomerular Diseases Work Group. KDIGO 2021 Clinical practice guideline for the management of glomerular diseases. Kidney Int. 2021 Oct;100(4s):S1-276.Texto completo Resumen
Sethi S, De Vriese AS, Fervenza FC. Acute glomerulonephritis. Lancet. 2022 Apr 23;399(10335):1646-63. Resumen
Walters GD, Willis NS, Cooper TE, et al. Interventions for renal vasculitis in adults. Cochrane Database Syst Rev. 2020 Jan 13;(1):CD003232.Texto completo Resumen
Artículos de referencia
Una lista completa de las fuentes a las que se hace referencia en este tema está disponible para los usuarios con acceso a todo BMJ Best Practice.
Diferenciales
- Nephrolithiasis
- Bladder cancer
- Renal cancer
Más DiferencialesGuías de práctica clínica
- KDIGO clinical practice guideline for antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitis
- KDIGO clinical practice guideline for the management of lupus nephritis
Más Guías de práctica clínicaFolletos para el paciente
Glomerulonephritis
Kidney infection
Más Folletos para el pacienteCalculadoras
Glomerular Filtration Rate Estimate by CKD-EPI Equation
Más CalculadorasInicie sesión o suscríbase para acceder a todo el BMJ Best Practice
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