Summary
Definition
History and exam
Risk factors
- family history of IgAN
- male sex
- age 20 to 30 years
- Asian/white/native American ancestry
- IgA vasculitis
- chronic liver disease
- HIV infection
Diagnostic investigations
1st investigations to order
- urinalysis
- urine microscopy and culture
- basic biochemistry, including estimated glomerular filtration rate (GFR)
- C3 and C4 complement levels
- renal ultrasound
- computed tomography (KUB)
- renal biopsy
Treatment algorithm
Contributors
Authors VIEW ALL
The Mayer Professor of Renal Medicine
Department of Infection, Immunity & Inflammation
University of Leicester
Honorary Consultant Nephrologist
John Walls Renal Unit
Leicester General Hospital
Head of the Postgraduate Specialty School of Clinical Academic Training
Health Education East Midlands
UK
Disclosures
JB has consultancies with Kancera AB, AduroBiotech, Anthera Pharmaceuticals, Calliditas, Novartis, Omeros, and EMD Serono. He is also an author of a number of references cited in this monograph.
Adjunct Assistant Professor
Deputy Head & Consultant
Department of Renal Medicine
Tan Tock Seng Hospital
Singapore
Disclosures
SCY is an author of a reference cited in this monograph.
Dr Jonathan Barratt and Dr See Cheng Yeo would like to gratefully acknowledge Dr Hani Bleibel and Dr Chike Nzerue, previous contributors to this monograph. HB and CN declare that they have no competing interests.
Peer reviewers VIEW ALL
Associate Professor of Medicine
Nephrology Division
Stanford University Medical Center
Stanford
CA
Disclosures
RL declares that he has no competing interests.
Professor of Nephrology
UCL Centre for Nephrology
Royal Free Hospital
London
UK
Disclosures
AS declares that he has no competing interests.
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