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Last reviewed: 27 Sep 2025
Last updated: 11 Feb 2025

Summary

Definição

História e exame físico

Principais fatores diagnósticos

  • potential exposure to measles
  • unvaccinated/incompletely vaccinated individuals
  • fever
  • cough
  • coryza
  • conjunctivitis
  • Koplik spots
  • maculopapular rash
Detalhes completos

Fatores de risco

  • exposure to measles virus
  • no prior immunization against measles
  • failure to respond to measles vaccine
Detalhes completos

Investigações diagnósticas

Primeiras investigações a serem solicitadas

  • measles-specific IgM and IgG serology (ELISA)
Detalhes completos

Investigações a serem consideradas

  • acute and convalescent sera for measles-specific IgG
  • measles RNA detection by PCR
  • antigen detection by fluorescent antibody or PCR techniques
  • isolation of virus in tissue culture system
Detalhes completos

Algoritmo de tratamento

AGUDA

all patients

Colaboradores

Autores

Elizabeth Barnett, MD

Professor of Pediatrics

Boston University School of Medicine

Boston Medical Center

Boston

MA

Declarações

EB receives clinical trial funds from Pfizer (COVID, PCV20, and RSV vaccines) and GSK (MMRV vaccine). She receives royalties from Elsevier (Immigrant Medicine), AAP (Nelson's antimicrobial therapy), and honoraria from AAP (Red Book). She participated in an Advisory Board (Sobi, RSV).

Revisores

Sharon Nachman, MD

Professor of Pediatrics

Division Chief Pediatric Infectious Disease

State University of New York at Stony Brook

Stony Brook

NY

Declarações

SN declares that she has no competing interests.

Linda Nield, MD, FAAP

Professor of Pediatrics

West Virginia University School of Medicine

Morgantown

WV

Declarações

LN is an author of a reference cited in this topic.

Aisha Sethi, MD

Assistant Professor of Medicine

Associate Residency Program Director

University of Chicago

Chicago

IL

Раскрытие информации

AS declares that she has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Список литературы

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Основные статьи

McLean HQ, Fiebelkorn AP, Temte JL, et al; Centers for Disease Control and Prevention. Prevention of measles, rubella, congenital rubella syndrome, and mumps, 2013: summary recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2013 Jun 14;62(RR-04):1-34.Полный текст  Аннотация

Centers for Disease Control and Prevention. Child and adolescent immunization schedule: recommendations for ages 18 years or younger, United States, 2025. Nov 2024 [internet publication].Полный текст

UK Health Security Agency. Measles: the green book, chapter 21. Dec 2019 [internet publication].Полный текст

Centers for Disease Control and Prevention. Adult immunization schedule: recommendations for ages 19 years or older, United States, 2025. Nov 2024 [internet publication].Полный текст

Committee on Infectious Diseases, American Academy of Pediatrics. Measles. In: Kimberlin DW, Banerjee R, Barnett ED, et al, eds. Red Book: 2024-2027 Report of the Committee on Infectious Diseases. 33rd ed. Itasca, IL: American Academy of Pediatrics; 2024.Полный текст

Статьи, указанные как источники

A full list of sources referenced in this topic is available here.

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