Last reviewed: 5 Jul 2021
Last updated: 04 Jun 2021

Summary

Differentials

Common

  • Roseola infantum (sixth disease)
  • Erythema infectiosum (fifth disease)
  • Epstein-Barr virus (EBV) infection
  • COVID-19
  • Atopic dermatitis
  • Seborrheic dermatitis
  • Irritant contact dermatitis
  • Pityriasis rosea
  • Impetigo
  • Tinea corporis
  • Tinea capitis
  • Scabies
  • Insect bites or stings
  • Erythema toxicum neonatorum
  • Child abuse
  • Self-harm/dermatitis artefacta
  • Cutaneous candidiasis
  • Cutaneous herpes simplex
  • Molluscum contagiosum

Uncommon

  • Varicella-zoster
  • Measles (rubeola)
  • Cytomegalovirus (CMV) infection
  • Dengue fever
  • HIV seroconversion
  • Rubella (German measles)
  • Hand-foot-and-mouth disease
  • Allergic contact dermatitis
  • Psoriasis
  • Mastocytosis
  • Folliculitis
  • Rocky Mountain spotted fever
  • Lyme disease
  • Simple drug eruption
  • Anaphylaxis
  • Chemotherapy
  • Stevens-Johnson syndrome/toxic epidermal necrolysis
  • Drug reaction with eosinophilia and systemic symptoms (DRESS)
  • Erythema multiforme
  • Meningococcal disease
  • Scarlet fever
  • Staphylococcal scalded skin syndrome
  • Toxic shock syndrome
  • Syphilis
  • Gonorrhea
  • Infective endocarditis
  • Food allergy
  • Leukemia
  • Immune thrombocytopenia
  • Kawasaki disease
  • Juvenile arthritis
  • IgA vasculitis (formerly known as Henoch-Schonlein purpura)
  • Systemic lupus erythematosus
  • Rheumatic fever
  • Sarcoidosis
  • Miliaria crystallina
  • Transient neonatal pustular melanosis

Contributors

Authors

Patricia Treadwell, MD

Professor Emeritus of Pediatrics and Dermatology

Indiana University School of Medicine

Riley Hospital for Children

Indianapolis

IN

Disclosures

PT declares that her spouse owns stocks in Eli Lilly and Company.

Peer reviewers

Nanette Silverberg, MD

Clinical Professor of Dermatology

Columbia University College of Physicians and Surgeons

New York City

NY

Disclosures

NS declares that she has no competing interests.

Hugo van Bever, MD, PhD

Professor in Pediatrics

Department of Pediatrics

National University Hospital

Singapore

Disclosures

HVB declares that he has no competing interests.

Linda Nield, MD, FAAP

Associate Professor of Pediatrics

West Virginia University School of Medicine

Morgantown

WV

Disclosures

LN is an author of a reference cited in this topic.

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