Management should be reviewed periodically with all patients. This should include:
When to contact the healthcare provider
Blood glucose goals and the use of supplemental short- or rapid-acting insulin during illness
Means to suppress fever and treat infection
Initiation of an easily digestible fluid diet containing electrolytes and glucose during illness.
Patients should be advised to always continue insulin during illness and to seek professional advice early.
Sodium-glucose cotransporter 2 (SGLT-2) inhibitor-associated DKA in patients with type 2 diabetes is typically precipitated by insulin omission or significant dose reduction, severe acute illness, dehydration, extensive exercise, surgery, low-carbohydrate diets, or excessive alcohol intake. DKA prevention strategies should include withholding SGLT-2 inhibitors when precipitants are present, and avoiding insulin omission or large insulin dose reduction.
The patient (or family member or carer) must be able to accurately measure and record blood glucose, insulin administration, temperature, respiratory rate, and pulse. Blood ketone (BOHB) should be checked when blood glucose is >300 mg/dL and, if it is high, the patient should present to the hospital for further evaluation. The frequency of blood glucose monitoring depends on the patient's clinical condition: in uncontrolled diabetes (HbA1c >7.0%), it is recommended to check blood glucose before each meal, plus at bedtime.
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