Last reviewed: June 2020
Last updated: June  2020

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • persistent cough
  • dry cough
  • prolonged symptoms
  • fever
  • pneumonia on physical examination
  • exposure to a person with respiratory tract infection

Other diagnostic factors

  • throat involvement
  • rash
  • headache
  • bullous myringitis
  • hepatitis
  • urethritis
  • cervicitis
  • pelvic pain

Risk factors

  • close community settings
  • recent exposure
  • cigarette smoking
  • immunosuppression
  • asplenia
  • age <30 years

Diagnostic investigations

1st investigations to order

  • WBC count
  • haemoglobin
  • LFTs
  • oxygen saturation
  • urea
  • chest x-ray
More 1st investigations to order

Investigations to consider

  • polymerase chain reaction
  • serology
  • nasopharyngeal viral cultures
  • culture/Gram stain
More investigations to consider

Treatment algorithm

Contributors

Ran Nir-Paz

Associate Professor in Medicine

Department of Clinical Microbiology and Infectious Diseases

Hadassah-Hebrew University Medical Center

Jerusalem

Israel

Disclosures

RNP has received research grants from US-Israel Binational Science Foundation, Hebrew University, Rosetrees Trust, and SpeeDx Ltd. RNP is chair of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Mycoplasma and Chlamydia Infections (ESGMAC). RNP is a consultant for and has stocks in eDAS Healthcare. RNP is an author of several references cited in this topic.

Peer reviewersVIEW ALL

Director

Institute for Medical Microbiology and Hygiene

Dresden

Germany

Disclosures

EJ declares that he has no competing interests.

Research Scientist

Pediatric Infectious Disease

California Department of Public Health

Viral and Rickettsial Disease Laboratory

Richmond

CA

Disclosures

LC declares that she has no competing interests.

Use of this content is subject to our disclaimer