最后审阅: 6 十一月 2021
最后更新: 13 五月 2021

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 伴有毛细血管扩张的丘疹
  • 斑块,结节,有卷边的肿瘤
  • 小痂及不易愈合的伤口
  • 不易愈合的痂
  • 珍珠白色结节和/或斑块

其他诊断因素

  • 与大的或被忽视的基底细胞癌相关的转移
  • 进展期皮损的局部破坏

危险因素

  • 紫外线(UV)辐照
  • 光暴露
  • x线暴露
  • 三氧化二砷暴露
  • Hedgehog 信号通路异常
  • 着色性干皮病
  • 痣样基底细胞癌(Gorlin-Goltz)综合征
  • 非黑色素瘤皮肤癌病史
  • 儿童期肿瘤存活者
  • 移植后患者

诊断性检查

首要检查

  • 皮肤病理组织学活检

新兴检查

  • 体内多光子显微镜

治疗流程

撰稿人

作者

Robert A. Schwartz, MD, MPH, FAAD, FRCP (Edin)
Robert A. Schwartz

Professor & Head

Dermatology

Rutgers University New Jersey Medical School

Newark

NJ

Honorary Professor

China Medical University

Shenyang

China

Honorary Professor

Sree Balaji Medical College

Bharath University

Chennai

India

利益声明

RAS declares that he has no competing interests. RAS is an author of a number of references cited in this topic.

鸣谢

Professor Robert A. Schwartz would like to gratefully acknowledge Dr James R. DeBloom and Dr Drazen Jukic, the previous contributors to this topic. JRD and DJ declare that they have no competing interests.

同行评议者

Richard Bull, BMBCh

Consultant Dermatologist

Homerton University Hospital NHS Foundation Trust

London

UK

利益声明

RB declares that he has no competing interests.

David Cassarino, MD, PhD

Assistant Professor

Department of Pathology and Laboratory Medicine

University of California

Los Angeles

CA

利益声明

DC declares that he has no competing interests.

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