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恶性肿瘤性高钙血症

最后审阅: 5 Oct 2024
最后更新: 18 Jul 2023

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 恶性肿瘤史
完整详情

其他诊断因素

  • 正常体格检查
  • 皮肤张力差和/或粘膜干燥
  • 意识模糊
  • 疲劳
  • 便秘
  • 食欲不振
  • 恶心
  • 多尿
  • 多饮
  • 骨痛
  • 使用诱发高钙血症的药物
  • 木僵
  • 昏迷
完整详情

危险因素

  • 非转移性恶性肿瘤
  • 转移性骨骼受累
  • 淋巴瘤
完整详情

诊断性检查

首要检查

  • 血清总钙
  • 血清游离钙
  • 血清白蛋白
  • 全套代谢功能检测
  • 静息心电图 (ECG)
  • 血清甲状旁腺素
  • 血清甲状旁腺素相关肽
  • 血清磷
  • 血清骨化三醇(1,25-二羟维生素D)
  • 血清 25 -羟基维生素 D
完整详情

需考虑的检查

  • 骨骼检查
  • 胸部 X 线检查
完整详情

治疗流程

急症处理

轻度高钙血症或无症状的中度高钙血症

有症状的中度或重度高钙血症:无晚期肾病

有症状的中度或重度高钙血症:伴晚期肾病

撰稿人

作者

Albert Shieh, MD

Assistant Professor of Medicine

Division of Geriatric Medicine

Department of Medicine

University of California, Los Angeles

Los Angeles

CA

利益声明

AS declares that he has no competing interests.

Dorothy Martinez, MD

Clinical Professor of Medicine

Division of Endocrinology

Department of Medicine

University of California, Los Angeles

Los Angeles

CA

利益声明

DM declares that she has no competing interests.

同行评议者

Ken C. Chiu, MD, FACE

Professor

Endocrinology Fellowship Training Program

Department of Clinical Diabetes, Endocrinology, and Metabolism

City of Hope National Medical Center

Duarte

CA

利益声明

KCC declares that he has no competing interests.

Richard Quinton, MD

Consultant and Senior Lecturer

Endocrine Unit

Newcastle University and Royal Victoria Infirmary

Newcastle-upon-Tyne

UK

利益声明

RQ has been reimbursed by Amgen, the manufacturer of Cinacalcet, for attending a conference and for giving an educational seminar (total under £1,200 over past 3 years).

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