Resumo
Definição
História e exame físico
Principais fatores diagnósticos
- miastenia gravis
- fraqueza muscular
- edema facial e de membros superiores
- pletora facial
- veias dilatadas no pescoço e parede torácica e/ou abdominal
- edema no braço esquerdo
Outros fatores diagnósticos
- tosse
- dispneia
- febre e/ou perda de peso
Fatores de risco
- história de miastenia gravis
- idade >45 anos
Investigações diagnósticas
Primeiras investigações a serem solicitadas
- radiografia torácica
- tomografia computadorizada (TC) do tórax com meio de contraste intravenoso
Investigações a serem consideradas
- ressonância nuclear magnética (RNM) do tórax
- biópsia tecidual
- anticorpos contra o receptor da acetilcolina
- Hemograma completo
Novos exames
- tomografia por emissão de pósitrons/tomografia computadorizada (PET/TC)
Algoritmo de tratamento
tumor ressecável
tumor localmente avançado
tumor recorrente
Colaboradores
Autores
Douglas Z. Liou, MD
Clinical Assistant Professor of Cardiothoracic Surgery
Division of Thoracic Surgery
Stanford University School of Medicine
Stanford
CA
Declarações
DZL declares that he has no competing interests.
Joseph B. Shrager, MD
Professor of Cardiothoracic Surgery
Chief, Division of Thoracic Surgery
Medical Director, Thoracic Oncology CCP
Stanford University School of Medicine / Stanford Cancer Institute
Stanford
CA
Declarações
JBS declares that he has no competing interests.
Agradecimentos
Dr Douglas Z. Liou and Dr Joseph B. Shrager would like to gratefully acknowledge Dr Tracey Evans, Dr Nicholas Choong, Dr Mario Gasparri, and Dr Cameron Wright, previous contributors to this topic.
Declarações
TE has received consultancy fees from Genentech and Celgene. She is a board member of Wissahickon Hospice. Educational events include an annual thoracic educational series sponsored by Imedex. NC and MG declare that they have no competing interests. CW is an author of a number of references cited in this topic.
Revisores
Kenneth Kesler, MD
Professor of Surgery
Division of Cardiothoracic Surgery
Department of Surgery
Indiana University School of Medicine
Indianapolis
IN
Declarações
KK declares that he has no competing interests.
James Huang, MD
Assistant Attending Surgeon
Thoracic Service
Memorial Sloan-Kettering Cancer Center
New York
NY
Declarações
JH is an author of a number of references cited in this topic.
Enrico Ruffini, MD
Associate Professor
Thoracic Surgery
University of Torino
Torino
Italy
Declarações
ER is an author of a reference cited in this topic.
Diagnósticos diferenciais
- Linfoma
- Tumor mediastinal maligno de células germinativas: seminoma
- Tumor mediastinal de células germinativas: não seminoma
Mais Diagnósticos diferenciaisDiretrizes
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