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Actinomicose

Last reviewed: 3 Dec 2025
Last updated: 11 May 2023

Summary

Definition

History and exam

Key diagnostic factors

  • presença de fatores de risco
  • edema de tecidos moles
Full details

Other diagnostic factors

  • diversos tratos sinusais
  • descoloração da pele
  • dificuldades de mastigação
  • sintomas constitucionais
  • alteração nos hábitos intestinais
  • desconforto abdominal
  • náuseas e vômitos
  • sensação de massa abdominal
  • sangramento ou corrimento vaginal
  • tosse produtiva ou seca
  • expectoração raiada de sangue
  • dispneia
  • dor torácica
  • defeitos neurológicos focais
Full details

Risk factors

  • sexo masculino
  • lesão ou inflamação da cavidade oral
  • diabetes mellitus
  • imunossupressão
  • dano tecidual local por neoplasia, trauma ou irradiação
  • dispositivo intrauterino
  • aspiração
Full details

Diagnostic investigations

1st investigations to order

  • cultura de pus ou tecido afetado
  • histologia do tecido afetado
  • imuno-histologia
  • Hemograma completo
  • tomografia computadorizada (TC) ou ressonância nuclear magnética (RNM) abdominal
Full details

Emerging tests

  • reação em cadeia da polimerase do tecido afetado

Treatment algorithm

ACUTE

não alérgicos à penicilina

alergia à penicilina

Contributors

Authors

Thomas Schneider, MD, PhD

Professor

Medical Department I

Charité - University Medicine Berlin

CBF

Berlin

Germany

Disclosures

TS is an author of a number of references cited in this topic.

Verena Moos, PhD

Scientist

Medical Department I

Charité - University Medicine Berlin

CBF

Berlin

Germany

Disclosures

VM is an author of a number of references cited in this topic.

Peer reviewers

Johannes R. Bogner, MD

Professor of Internal Medicine

Department of Infectious Diseases

Medical Polyclinic

University Hospital Munich

Munich

Germany

Disclosures

JRB declares that he has no competing interests.

Chris Huston, MD

Assistant Professor of Medicine

Division of Infectious Diseases

University of Vermont

Burlington

VT

Disclosures

CH declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Smego RA Jr, Foglia G. Actinomycosis. Clin Infect Dis. 1998 Jun;26(6):1255-61. Abstract

Acevedo F, Baudrand R, Letelier LM, et al. Actinomycosis: a great pretender: case reports of unusual presentations and a review of the literature. Int J Infect Dis. 2008 Jul;12(4):358-62. Abstract

Wong VK, Turmezei TD, Weston VC. Actinomycosis. BMJ. 2011 Oct 11;343:d6099. Abstract

Martin MV. The use of oral amoxycillin for the treatment of actinomycosis: a clinical and in vitro study. Br Dent J. 1984 Apr 7;156(7):252-4. Abstract

Spilsbury BW, Johnstone FR. The clinical course of actinomycotic infections: a report of 14 cases. Can J Surg. 1962 Jan;5:33-48. Abstract

Sudhakar SS, Ross JJ. Short-term treatment of actinomycosis: two cases and a review. Clin Infect Dis. 2004 Feb 1;38(3):444-7.Full text  Abstract

Bennhoff DF. Actinomycosis: diagnostic and therapeutic considerations and a review of 32 cases. Laryngoscope. 1984 Sep;94(9):1198-217. Abstract

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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