Summary
Definition
History and exam
Key diagnostic factors
- gestación >20 semanas
- PA sistólica ≥140 mmHg y/o PA diastólica ≥90 mmHg y previamente normotensa
- cefalea
- dolor abdominal superior
Other diagnostic factors
- movimiento fetal reducido
- retraso del crecimiento fetal
- edema
- alteraciones visuales
- convulsiones
- dificultad para respirar
- oliguria
- hiperreflexia con clonus sostenido.
Risk factors
- nuliparidad
- preeclampsia en un embarazo anterior
- antecedentes familiares de preeclampsia
- índice de masa corporal (IMC) >30
- edad materna >40 años
- gestaciones múltiples
- subfertilidad
- hipertensión gestacional
- diabetes preexistente
- migraña
- síndrome del ovario poliquístico (SOPQ)
- enfermedad autoinmune
- nefropatía
- enfermedad cardiovascular preexistente e hipertensión crónica
- intervalo de ≥10 años desde el embarazo anterior
- residencia a gran altura
- hipotiroidismo.
Diagnostic investigations
1st investigations to order
- análisis de orina
- ultrasonido fetal
- velocimetría Doppler de la arteria umbilical
- evaluación del líquido amniótico
- cardiotocografía fetal
- hemograma completo (HC)
- pruebas de función hepática
- creatinina sérica
- factor de crecimiento placentario
Investigations to consider
- cribado de coagulación
Treatment algorithm
antes del parto
después del parto
Contributors
Authors
James J. Walker, MD, FRCPS (Glas), FRCP (Edin), FRCOG

Clinical Director
Maternity Investigation Team
Healthcare Services Investigation Branch
Hampshire
UK
Disclosures
JJW is Honorary President of the Baby Lifeline Training Company and Honorary Medical Director of Action on Pre-eclampsia. He lectures and teaches on pre-eclampsia and maternal safety both nationally and internationally, and is the author of national and local reports into safety investigations for the Healthcare Services Investigation Branch and national and local bodies as Clinical Director.
Lara Morley, MBCHB, BSc, PgCert, PhD, MRCOG, FHEA
NIHR-Clinical Lecturer and Subspecialty Trainee in Reproductive Medicine and Surgery
Leeds Institute of Cardiovascular and Metabolic Medicine
University of Leeds
Leeds
UK
Disclosures
LM declares that she has no competing interests.
Jacqueline Clarke, MBBS, PgG Cert, MRCOG, PG Cert
Consultant Obstetrician
Leeds Teaching Hospitals Trust
Leeds
UK
Disclosures
JC declares that she has no competing interests.
Peer reviewers
Thomas R. Easterling, MD
Professor
Department of Obstetrics & Gynecology
University of Washington
Seattle
WA
Disclosures
TRE declares that he has no competing interests.
Andrew Shennan, MBBS, MD FRCOG
Professor of Obstetrics
Maternal and Fetal Research Unit
St Thomas' Hospital
King's College London
London
UK
Declarações
Not disclosed.
Referências
Principais artigos
American College of Obstetricians and Gynecologists. Practice bulletin no. 222: gestational hypertension and preeclampsia. Jun 2020 [internet publication].Texto completo
Magee LA, Brown MA, Hall DR, et al. The 2021 International Society for the Study of Hypertension in Pregnancy classification, diagnosis & management recommendations for international practice. Pregnancy Hypertens. 2022 Mar;27:148-69. Resumo
National Institute for Health and Care Excellence. Hypertension in pregnancy: diagnosis and management. Apr 2023 [internet publication].Texto completo
Poon LC, Shennan A, Hyett JA, et al. The International Federation of Gynecology and Obstetrics (FIGO) initiative on pre-eclampsia: a pragmatic guide for first-trimester screening and prevention. Int J Gynaecol Obstet. 2019 May;145 Suppl 1:1-33.Texto completo Resumo
National Institute for Health and Care Excellence. PLGF-based testing to help diagnose suspected preterm pre-eclampsia. Jul 2022 [internet publication].Texto completo
Artigos de referência
Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
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