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Actinomicosis

Last reviewed: 8 Dec 2025
Last updated: 11 May 2023

Summary

Definition

History and exam

Key diagnostic factors

  • presencia de factores de riesgo
  • inflamación de los tejidos blandos
Full details

Other diagnostic factors

  • múltiples fístulas
  • pigmentación de la piel
  • dificultad al masticar
  • síntomas constitucionales
  • cambio en el ritmo intestinal
  • molestias abdominales
  • náuseas y vómitos
  • sensación de masa abdominal
  • secreción o sangrado vaginal
  • tos seca o productiva
  • esputo con sangre
  • disnea
  • dolor torácico
  • defectos neurológicos focales
Full details

Risk factors

  • sexo masculino
  • lesión o inflamación de la cavidad oral
  • diabetes mellitus
  • inmunosupresión
  • daño tisular local causado por neoplasia, traumatismo o irradiación
  • dispositivo intrauterino
  • aspiración
Full details

Diagnostic investigations

1st investigations to order

  • cultivo de pus o tejido afectado
  • histología del tejido afectado
  • inmunohistología
  • hemograma completo (HC)
  • tomografía computarizada (TC) o resonancia magnética (IRM) de abdomen
Full details

Emerging tests

  • reacción en cadena de la polimerasa (PCR) del tejido afectado

Treatment algorithm

ACUTE

no alérgico a la penicilina

paciente alérgico a la penicilina

Contributors

Authors

Thomas Schneider, MD, PhD

Professor

Medical Department I

Charité - University Medicine Berlin

CBF

Berlin

Germany

Disclosures

TS is an author of a number of references cited in this topic.

Verena Moos, PhD

Scientist

Medical Department I

Charité - University Medicine Berlin

CBF

Berlin

Germany

Disclosures

VM is an author of a number of references cited in this topic.

Peer reviewers

Johannes R. Bogner, MD

Professor of Internal Medicine

Department of Infectious Diseases

Medical Polyclinic

University Hospital Munich

Munich

Germany

Disclosures

JRB declares that he has no competing interests.

Chris Huston, MD

Assistant Professor of Medicine

Division of Infectious Diseases

University of Vermont

Burlington

VT

Disclosures

CH declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Smego RA Jr, Foglia G. Actinomycosis. Clin Infect Dis. 1998 Jun;26(6):1255-61. Abstract

Acevedo F, Baudrand R, Letelier LM, et al. Actinomycosis: a great pretender: case reports of unusual presentations and a review of the literature. Int J Infect Dis. 2008 Jul;12(4):358-62. Abstract

Wong VK, Turmezei TD, Weston VC. Actinomycosis. BMJ. 2011 Oct 11;343:d6099. Abstract

Martin MV. The use of oral amoxycillin for the treatment of actinomycosis: a clinical and in vitro study. Br Dent J. 1984 Apr 7;156(7):252-4. Abstract

Spilsbury BW, Johnstone FR. The clinical course of actinomycotic infections: a report of 14 cases. Can J Surg. 1962 Jan;5:33-48. Abstract

Sudhakar SS, Ross JJ. Short-term treatment of actinomycosis: two cases and a review. Clin Infect Dis. 2004 Feb 1;38(3):444-7.Full text  Abstract

Bennhoff DF. Actinomycosis: diagnostic and therapeutic considerations and a review of 32 cases. Laryngoscope. 1984 Sep;94(9):1198-217. Abstract

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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