Criteria
Centers for Disease Control and Prevention (CDC) 2024 case definition:[46]
Clinical criteria:
Acute onset of flaccid paralysis with decreased or absent tendon reflexes in the affected limbs, particularly in the absence of a more plausible diagnosis.
Laboratory criteria for confirmation:
Poliovirus detected by sequencing of the capsid region of the genome by the CDC Poliovirus Laboratory,
Poliovirus detected in an appropriate clinical specimen (e.g., stool [preferred], cerebrospinal fluid, oropharyngeal secretions) using a properly validated assay, and specimen unavailable for sequencing by the CDC Poliovirus Laboratory.
Criteria to distinguish new cases:
Post-polio syndrome is a condition that can affect survivors of poliovirus infection decades after recovering from their initial infection. A person with post-polio syndrome should not be enumerated as a new case.
Subtype(s) case definition and classification:
Poliovirus, nonparalytic poliovirus infection
Confirmed: meets confirmatory laboratory evidence.
Poliovirus, paralytic poliomyelitis
Meets clinical criteria and confirmatory laboratory evidence.
Use of this content is subject to our disclaimer