Last reviewed: 23 Sep 2021
Last updated: 18 Aug 2021

Summary

Definition

History and exam

Key diagnostic factors

  • cough
  • inspiratory whooping
  • rhinorrhea
  • posttussive vomiting

Other diagnostic factors

  • sneezing
  • absent or low-grade fever
  • decreased appetite
  • apnea

Risk factors

  • age <6 months
  • baby born to mother who became infected at ≥34 weeks gestation
  • no or incomplete immunization
  • school teachers or healthcare workers (transmission)
  • close contact with an infected person, especially a sibling
  • household contact with an infected person

Diagnostic investigations

1st investigations to order

  • culture of a nasopharyngeal aspirate or swab from the posterior nasopharynx
  • PCR of nasopharyngeal aspirate
  • serology
  • CBC

Treatment algorithm

Contributors

Authors

M. Nawal Lutfiyya, PhD, FACE

Senior Research Scientist

Academic Health Center

University of Minnesota

Twin Cities Campus

Minneapolis

MN

Disclosures

MNL declares that she has no competing interests.

Carrie Sharkey-Asner, MD

Clinical Assistant Professor

Department of Family and Community Medicine

University of Illinois-Chicago

College of Medicine

Chicago

IL

Disclosures

CSA declares that she has no competing interests.

Peer reviewers

Anette Faye-Lund, MD

Department of Pediatrics

Hospital of Vestfold

Toensberg

Norway

Disclosures

AFL declares that she has no competing interests.

Alexander K.C. Leung, MBBS

Pediatric Consultant

Alberta Children's Hospital

University of Calgary

Alberta

Canada

Disclosures

AKCL declares that he has no competing interests.

Use of this content is subject to our disclaimer