Summary
Definition
History and exam
Key diagnostic factors
- cough with increasing sputum production
- dyspnoea
- pleuritic chest pain
- rigors or night sweats
- fever
- abnormal auscultatory findings
- confusion
- presence of risk factors
Other diagnostic factors
- myalgia
- malaise
- anorexia
- lethargy
- worsening of pre-existing conditions
- sore throat
- headache
- nausea
- abdominal pain
- diarrhoea
Risk factors
- age >65 years
- residence in a healthcare setting
- COPD
- exposure to cigarette smoke
- alcohol abuse
- poor oral hygiene
- use of acid-reducing drugs
- contact with children
- diabetes mellitus
- chronic renal disease
- chronic liver disease
- use of opioids
Diagnostic investigations
1st investigations to order
- chest x-ray
- pulse oximetry
- arterial blood gas (ABG)
- urea and electrolytes
- full blood count
- C-reactive protein (CRP)
- liver function tests
Investigations to consider
- blood culture
- sputum culture (± Gram stain)
- urinary antigen testing for legionella and pneumococcus
- polymerase chain reaction (PCR) and/or serological tests
- CT scan of chest
- chest ultrasound
- thoracocentesis and pleural fluid culture
- computer tomographic pulmonary angiography (CTPA)
- bronchoscopy
- serum procalcitonin
- point-of-care CRP
Treatment algorithm
Contributors
Expert advisers
Jonathan Bennett, MD
Honorary Professor of Respiratory Sciences
University of Leicester
Respiratory Consultant
Glenfield Hospital
Leicester
UK
Biography
JB is deputy medical director RCP Invited service Reviews, and speaker at National Society (e.g., BTS), Primary Care respiratory Society, and Society Cardiothoracic Surgeons meetings.
Disclosures
JB declares that he has no competing interests.
Acknowledgements
BMJ Best Practice would like to gratefully acknowledge the previous team of expert contributors, whose work has been retained in parts of the content:
Catia Cilloniz MSc, PhD
Post-doctoral Research
Pneumology Department
Hospital Clinic of Barcelona
CIBERES
IDIBAPS
Barcelona
Spain
Antoni Torres MD, PhD
Professor of Medicine
Director
Pulmonary Intensive Care Unit
Respiratory Institute
Hospital Clinic of Barcelona
Barcelona
Spain
Disclosures
CC and AT are each authors of a number of references cited in this topic.
Peer reviewers
Wei Shen Lim
Consultant Respiratory Physician and Honorary Professor of Medicine
Nottingham University Hospitals NHS Trust
Nottingham
UK
Disclosures
WSL was chairman of the British Thoracic Society community-acquired pneumonia guidelines committee and a member of the guideline development group for the National Institute for Health and Care Excellence pneumonia guidelines. His institution has received unrestricted investigator-initiated research funding from Pfizer for a multicentre study of pneumococcal pneumonia in which he was the chief investigator, and research funding from the National Institute for Health Research for studies in pneumonia in which he was the principal investigator. He is also an author of at least one reference cited in the topic.
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