小结
定义
病史和体格检查
关键诊断因素
- 存在的危险因素
- 阵挛
- 反射亢进
其他诊断因素
- 焦虑
- 激越
- 意识模糊
- 震颤，寒战，肌肉抽搐
- 出汗
- 头痛
- 心动过速
- 张力过高 / 强直
- 发汗
- 冲洗
- 瞳孔放大
- 体温过高
- 肌阵挛
- 惊吓
危险因素
- 暴露于 5-羟色胺能药物
- 暴露于两种或以上 5-羟色胺能药物
诊断性检查
首要检查
- 临床诊断
需考虑的检查
- 全血细胞计数 (FBC）
- 肌酸磷酸激酶
- 心电图 (ECG)
- 血培养
- 腰椎穿刺：
- 头部 CT 或 MRI（核磁共振）
治疗流程
重度 5-羟色胺中毒
中度 5-羟色胺中毒
轻度 5-羟色胺中毒
撰稿人
作者
Geoffrey Isbister, BSc, MBBS, FACEM, MD
Clinical Toxicologist
Calvary Mater Newcastle
Associate Professor
University of Newcastle
Newcastle
Australia
利益声明
GI is an author of several references cited in this monograph.
同行评议者
Laura Tormoehlen, MD, FAAN, FACMT
Neurologist and Medical Toxicologist
Associate Professor of Clinical Neurology and Emergency Medicine
Indiana University
Bloomington
IN
利益声明
LT has been compensated as an expert witness for cases involving serotonergic drugs.
Daniel E Brooks, MD
Medical Director
Banner Poison and Drug Information Center
Phoenix
AZ
利益声明
DEB declares that he has no competing interests.
Karl Marlowe, MbChB, MSc, PgC-Ed, PgD-CBT, MRCPsych
Consultant Psychiatrist
East London NHS Foundation Trust
London
UK
利益声明
KM declares that he has no competing interests.
Theodore A. Stern, MD
Chief
Psychiatric Consultation Service
Massachusetts General Hospital
Professor of Psychiatry
Harvard Medical School
Boston
MA
利益声明
TAS declares that he has no competing interests.
Paul M. Gahlinger, MD
Adjunct Professor
Department of Family and Preventive Medicine
University of Utah
Salt Lake City
UT
利益声明
PMG declares that he has no competing interests.
鉴别诊断
- 神经阻滞剂恶性综合征 (NMS)
- 拟交感神经药物中毒
- 抗胆碱能药诱导的谵妄
更多 鉴别诊断患者教育信息
脑膜炎和败血病
5-羟色胺综合征
更多 患者教育信息
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