最近审阅: 27 十月 2020
最近更新: 14 十一月 2018

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 腹胀或腹部不适
  • 脾肿大

其他诊断因素

  • 虚弱和疲乏
  • 苍白和出血点
  • 发热
  • 复发性感染
  • 肝肿大
  • 浅表和深部淋巴结肿大
  • 神经系统异常
  • 相关系统性免疫疾病

危险因素

  • 中年
  • 男性
  • 白人血统
  • 西半球的位置
  • 环境暴露
  • 遗传易感性
  • EB病毒
  • 传染性单核细胞增多症

诊断性检查

首要检查

  • 全血细胞计数 (FBC)
  • 外周血涂片
更多 首要检查

需考虑的检查

  • 骨髓穿刺或活检
  • 免疫表型
  • 流式细胞仪
  • 耐酒石酸盐酸性磷酸酶(TRAP)染色
  • 腹部 CT
更多 需考虑的检查

新兴检查

  • 遗传学/分子学检测
更多 新兴检查

治疗流程

撰稿人

Associate Professor

USF Center for Comparative Effectiveness Research and Evidence Based Medicine

Department of Internal Medicine, College of Medicine

Moffitt Cancer Center & Research Institute, Department of Health Outcomes & Behavior

University of South Florida

Tampa

FL

利益声明

AK declares that he has no competing interests.

Professor

Division of Hematology-Oncology

Blood and Marrow Transplantation Program

Mayo Clinic

Jacksonville

FL

利益声明

MKD declares that he has no competing interests.

Dr Ambuj Kumar and Dr Mohamed Kharfan-Dabaja would like to gratefully acknowledge Dr Benjamin Djulbegovic, a previous contributor to this topic. BD declares that he has no competing interests.

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Consultant Haemato-Oncologist

Section of Haemato-Oncology

Brookes Lawley Institute of Cancer

Sutton

UK

利益声明

DC declares that he has no competing interests.

Clinical Professor of Medicine

University of Texas Health Science Center San Antonio

San Antonio

TX

利益声明

RL declares that he has no competing interests.

Chief Fellow

Section of Hematology and Oncology

Department of Internal Medicine

Wake Forest University Baptist Medical Center

Winston-Salem

NC

利益声明

RC declares that she has no competing interests.

Consultant Hematologist

The Royal Marsden Hospital

Sutton

Surrey

UK

利益声明

CD declares that she has no competing interests.

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