最近审阅: 28 十月 2020
最近更新: 08 二月 2019

小结

定义

病史和体格检查

关键诊断因素

  • 疾病进展
  • 虚弱
  • 感觉改变
  • 深部腱反射减弱

其他诊断因素

  • 共济失调
  • 40 至 60 岁
  • 近期感染
  • 未接触引发神经病的药物
  • 呼吸困难
  • 面部无力
  • 构音障碍
  • 吞咽困难
  • 尿失禁
  • 尿急或排尿踌躇
  • 阳痿
  • 体位性低血压
  • 视神经乳头水肿
  • 视力丧失
  • 痉挛状态
  • 共济失调

危险因素

  • 男性
  • 自身免疫性疾病
  • 糖尿病
  • 感染
  • 未定性的单克隆丙种球蛋白病 (MGUS)

诊断性检查

首要检查

  • 神经传导检查 (NCS)
  • 脑脊液 (CSF) 评估
更多 首要检查

需考虑的检查

  • 神经活检
  • 脊柱 MRI 检查
  • 神经超声
  • 酶联免疫吸附测定 (ELISA) 或蛋白质印迹法检测自身抗体
  • 免疫抑制剂的临床试验
更多 需考虑的检查

治疗流程

撰稿人

Glenn Lopate

Professor of Neurology

Department of Neurology

Washington University School of Medicine

St. Louis

MO

利益声明

GL is on the medical advisory board for Alnylam Pharmaceuticals and a consultant for Gerson Lehrman Group. GL is an author of a reference cited in this monograph.

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Partner

Phoenix Neurological Associates Ltd

Phoenix

AZ

利益声明

TL declares that he has no competing interests.

Professor

Cochrane Neuromuscular Disease Group

MRC Centre for Neuromuscular Disease

National Hospital for Neurology and Neurosurgery

London

UK

利益声明

RACH has held or holds consultancies with companies that produce intravenous immunoglobulin (CSL Behring, LFB, Octapharma, Kedrion, and Talecris) and with other companies that produce immunomodulatory drugs (Biogen-Idec and Ares-Serono). RACH has received grants from the UK Department of Health for the Cochrane Neuromuscular Disease Review Group, Sandoz (now Novartis), and Ares-Serono. RACH is an author of a number of references cited in this monograph.

Professor

CHU Dupuytren

Service et Laboratoire de Neurologie

Limoges

France

利益声明

Not disclosed.

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