妊娠期肝内胆汁淤积症

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最后审阅： 30 十二月 2022
最后更新： 10 十月 2017

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 除面部以外的瘙痒
  • 不伴皮疹的皮肤抓痕
更多 关键诊断因素

其他诊断因素

  • 轻度黄疸
其他诊断因素

危险因素

  • 妊娠期肝内胆汁淤积症 (ICP) 既往病史
  • 丙型肝炎病史
  • 妊娠期肝内胆汁淤积症家族史
  • 年龄 > 35 岁
  • 多胎妊娠
更多 危险因素
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诊断性检查

首要检查

  • 胆汁酸
  • 肝功能检查 (LFT)
  • 凝血指标
  • 空腹状态下血清胆固醇
  • 丙型肝炎病毒学
更多 首要检查

需考虑的检查

  • 肝脏活检
更多 需考虑的检查
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治疗流程

急症处理

具有症状的轻型（胆汁酸小于 40 µmol/L）

重型（胆汁酸大于等于 40 µmol/L）+ 孕周小于 37 周

重型（胆汁酸大于等于40 µmol/L）+ 孕周大于等于 37 周

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撰稿人

作者

Robert H. Debbs, DO, FACOOG

Associate Professor of Obstetrics and Gynecology

Division of Maternal Fetal Medicine

University of Pennsylvania School of Medicine

Director

Pennsylvania Hospital Maternal Fetal Medicine Network

Philadelphia

PA

利益声明

RHD declares that he has no competing interests.

鸣谢

Dr Robert H. Debbs would like to gratefully acknowledge Dr Derek Jurus, a previous contributor to this monograph. DJ declares that he has no competing interests.

同行评议者

Frank Lammert, MD

Director

Department of Internal Medicine II

Professor Internal Medicine

Saarland University Hospital

Homburg

Germany

利益声明

FL declares that he has no competing interests.

Ron Librizzi, DO, FACOOG

Director

Maternal Fetal Medicine

Virtua Health System

Associate Professor of Obstetrics and Gynecology

Thomas Jefferson University School of Medicine

Philadelphia

PA

利益声明

RL declares that he has no competing interests.

Vincenzo Berghella, MD, FACOG

Director

Maternal Fetal Medicine

Professor

Obstetrics and Gynecology

Thomas Jefferson University School of Medicine

Philadelphia

PA

利益声明

VB declares that he has no competing interests.

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