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Strabismus

Last reviewed: 2 Apr 2025
Last updated: 12 Nov 2024

Summary

Definition

History and exam

Key diagnostic factors

  • diplopia
  • eye misalignment
  • amblyopia
Full details

Other diagnostic factors

  • abnormal eye movements
  • visual confusion
  • asthenopia
  • intermittent closure of one eye
  • cranial nerve palsy
Full details

Risk factors

  • family history of strabismus
  • prematurity
  • low birth weight
  • maternal smoking during pregnancy
  • refractive error
Full details

Diagnostic investigations

1st investigations to order

  • cover test
  • simultaneous prism and cover test (SPCT)
  • uncover test (UCT)
  • alternate prism cover test (APCT)
  • Hirschberg test
  • Krimsky test
Full details

Investigations to consider

  • version testing
  • duction testing
  • forced duction testing
  • CT or MRI of orbit
  • MRI of brain
  • CT chest
Full details

Treatment algorithm

ACUTE

primary strabismus

secondary strabismus

Contributors

Authors

Daniel J. Salchow, MD
Daniel J. Salchow

Director

Pediatric Ophthalmology; Strabismus; Neuro-ophthalmology

Charité-Universitätsmedizin Berlin

Berlin

Germany

Disclosures

DJS declares that he has no competing interests.

Peer reviewers

Donny W. Suh, MD, FAAP, MBA, FACS

Chief and Professor of Pediatric Ophthalmology and Strabismus

Department of Ophthalmology

University of California, Irvine

Irvine

CA

Disclosures

DWS declares that he has no competing interests.

Peter Tiffin, BMedSci(Hons), MBBS, FRCOphth

Ophthalmology Consultant

City Hospitals Sunderland

Sunderland

UK

Disclosures

PT declares that he has no competing interests.

Jonathan Smith, MBBS, MRCP, MRCOphth

Specialist Registrar in Ophthalmology

Ophthalmics

Royal Victoria Infirmary

Newcastle

UK

Disclosures

JS declares that he has no competing interests.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

US Preventive Services Task Force. Vision in children ages 6 months to 5 years: screening. Sep 2017 [internet publication].Full text

Sprunger DT, Lambert SR, Hercinovic A, et al. Esotropia and exotropia preferred practice pattern®. Ophthalmology. 2023 Mar;130(3):P179-221.Full text  Abstract

Hutchinson AK, Morse CL, Hercinovic A, et al. Pediatric eye evaluations preferred practice pattern. Ophthalmology. 2023 Mar;130(3):P222-70.Full text  Abstract

Dagi LR, Velez FG, Holmes JM, et al. Adult strabismus preferred practice pattern®. Ophthalmology. 2024 Apr;131(4):P306-403.Full text

Cruz OA, Repka MX, Hercinovic A, et al. Amblyopia preferred practice pattern. Ophthalmology. 2023 Mar;130(3):P136-78.Full text  Abstract

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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