最近审阅: 1 十一月 2020
最近更新: 25 十月 2019

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 奶类、蛋类、坚果、鱼类、甲壳类动物、小麦或大豆的摄取
  • 可重现的症状
  • 潮红、荨麻疹或皮肤的血管性水肿
  • 喷嚏、流涕或鼻塞
  • 呼吸困难、气促、哮鸣、咳嗽或紫绀
  • 声音嘶哑、喘鸣或窒息感
  • 恶心和呕吐
  • 腹部绞痛或胃气胀
  • 腹泻
  • 结膜充血或流泪
  • 眼周水肿
  • 突发性症状
  • 由少量食物引起的反应
  • 其他过敏性疾病的表现
  • 喉水肿

其他诊断因素

  • 心动过速或心动过缓
  • 运动或劳累使病情恶化
  • 在反应前摄入酒精或药品
  • 心律失常
  • 低血压

危险因素

  • 食物过敏家族史
  • 特应性皮炎
  • 新生儿
  • 围产期花生油暴露

诊断性检查

首要检查

  • 体外IgE特异性的免疫测定法
  • 皮肤点刺试验
更多 首要检查

新兴检查

  • 过敏症斑贴试验
  • 成分分辨诊断试验
更多 新兴检查

治疗流程

撰稿人

A. Wesley Burks

Curnen Distinguished Professor and Chair

Department of Pediatrics

University of North Carolina

Chapel Hill

NC

利益声明

AWB receives grant support to his institution from the National Institutes of Health, Food Allergy Research & Education, and Allergen Research Corporation; royalties from UpToDate; consulting honorariums from Aravax, Astella Pharma Global Development, DBV Technologies and N-Fold, LLC, as well as Aimmune Therapeutics, Consortia TX, Inc., Intrommune Therapeutics, and Prota Therapeutics for his service on their respective Scientific Advisory Boards. AWB has consulted for the following companies (which are all now expired): Biomerica, Inc., Evelo Biosciences/Epiva, Genentech, Insys Therapeutics, PPD Development, Sanofi US Services, Valeant Pharmaceuticals North America, LLC, LEK Consulting, LLC, Hycor Biomedical. AWB has received payments for speaking at the Gordon Research Conferences, the Pediatric Allergy and Asthma Meeting, and the American College of Allergy Asthma and Immunology. AWB is a minority stockholder of both Allertein and Mastcell Pharmaceuticals stock. These interests do not directly relate to the article but are being shared for full disclosure. AWB is an author of references cited in this topic.

Associate Professor

Department of Pediatrics

Division of Allergy and Immunology

University of Texas Southwestern Medical Center

Dallas

TX

利益声明

JAB has received fees from Food Allergy Research and Education; personal fees and non-financial support from the American College of Allergy, Asthma and Immunology; grants from Nestle Health Sciences; personal fees from Nutricia North America; personal fees from Pharm-Olam International LTD; consulting work for and personal fees from Pfizer Pharmaceuticals; grants, personal fees and non-financial support from Aimmune Therapeutics; personal fees from Prota Therapeutics; personal fees from Allergy Therapeutics Ltd; grants from NIH-NIAID; grants from Novartis; personal fees from AllerGenis; personal fees from Abbott Nutrition International; grants and personal fees from DBV Technologies.

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Assistant Professor of Pediatric Allergy and Immunology

Mount Sinai School of Medicine

New York

NY

利益声明

JS declares that he has no competing interests.

Professor of Pediatrics

Mount Sinai School of Medicine

New York

NY

利益声明

HAS holds a 4% interest in a biotech company, Allertein Pharmaceuticals LLC, which is developing an engineered recombinant protein vaccine for peanut allergy, and 45% interest in a virtual company, Herbal Springs LLC, that holds a patent application on an herbal product for treating asthma and another for treating food allergy. HAS is an author of a number of references cited in this topic.

Consultant and Honorary Senior Lecturer in Paediatric Allergy

Evelina Children's Hospital

Guy's & St Thomas' Hospitals NHS Foundation Trust

London

UK

利益声明

AF declares that he has no competing interests.

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