小结
定义
病史和体格检查
关键诊断因素
- 存在的危险因素
- 肢端和口周色素脱失
- 肛周和外阴色素脱失
- 近期皮外伤
- 局部晒伤疼痛
- 利用 UV-A 曝光进行增强和荧光
- 晕痣
- 全身性色素脱失
危险因素
- 年龄＜30 岁
- family history of vitiligo
- 自身免疫性疾病
- 化学接触
诊断性检查
首要检查
- 临床诊断
需考虑的检查
- Wood’s lamp examination
- 皮肤活组织检查
治疗流程
节段性白癜风或局限性白癜风
广泛性白癜风（超过 3% 的体表面积）
撰稿人
作者
John E. Harris, MD, PhD
Professor
Department of Dermatology
University of Massachusetts Medical School
Worcester
MA
利益声明
JEH has acted as a consultant and/or investigator for: Pfizer, Genzyme/Sanofi, Aclaris Therapeutics Inc., Incyte, Rheos Medicines, Sun Pharmaceuticals, LEO Pharma, Villaris Therapeutics Inc., Dermavant, Temprian, AbbVie Inc., Janssen, TeVido, BioDevices, EMD Serono, Almirall, Boston Pharma, Sonoma Biotherapeutics Inc., Methuselah Health, Twi Biotech, Pandion, Cogen Therapeutics Inc., Admirx, BridgeBio, AnaptysBio, Avita, Frazier Management. He has equity in TeVido Biodevices, Rheos, and Villaris Therapeutics Inc., and is the Scientific Founder of Villaris Therapeutics Inc. JEH is an author of a number of references cited in this topic.
Mehdi Rashighi, MD
Assistant Professor
Department of Dermatology
University of Massachusetts Medical School
Worcester
MA
利益声明
MR has received consulting fees and/or research grants from the following: Pfizer, AbbVie, Dermavant, LEO Pharma, and Almirall. MR is an author of a reference cited in this topic.
鸣谢
Professor John E. Harris and Dr Mehdi Rashighi would like to gratefully acknowledge Dr Bernhard Ortel, a previous contributor to this topic. BO declares that he has no competing interests.
同行评议者
Iltefat Hamzavi, MD
Senior Staff Physician
Multicultural Dermatology Center
Henry Ford Hospital
Detroit
MI
利益声明
IH is an author of a number of references cited in this topic.
Piergiacomo Calzavara-Pinton, MD
Chair
Dermatology Department
University of Brescia
Brescia
Italy
利益声明
PC-P is an author of a number of references cited in this topic.
鉴别诊断
- 斑驳病
- Waardenburg 综合征
- 结节性硬化
更多 鉴别诊断指南
- British Association of Dermatologists guidelines for the management of people with vitiligo 2021
- Guidelines for the management of vitiligo
更多 指南
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