Summary
Definition
History and exam
Key diagnostic factors
- presence of risk factors
- acral and periorificial depigmentation
- perianal and genital depigmentation
- recent cutaneous trauma
- localised sunburn pain
- enhancement and fluorescence with UV-A exposure
- halo naevus
- universal depigmentation
- lip depigmentation
- erythema, oedema, or blistering
- retinal depigmentation
Diagnostic investigations
Treatment algorithm
Contributors
Authors VIEW ALL
Associate Professor
Department of Dermatology
University of Massachusetts Medical School
Worcester
MA
Disclosures
JEH has received consulting fees and/or research grants from the following: Pfizer, AbbVie, Combe, Concert Pharmaceuticals, Stiefel/GSK, Mitsubishi Tanabe Pharma, Novartis, Aclaris Therapeutics, The Expert Institute, Celgene, Biologics MD, Gliknik, Janssen, TeVido BioDevices, EMD Serono, 3rd Rock Ventures, Sun Pharmaceuticals and Dermira. JEH is an author of a number of references cited in this topic.
Physician Resident
Department of Dermatology
University of Massachusetts Medical School
Worcester
MA
Disclosures
MR is an author of a number of references cited in this topic.
Dr John E. Harris and Dr Mehdi Rashighi would like to gratefully acknowledge Dr Bernhard Ortel, a previous contributor to this topic. BO declares that he has no competing interests.
Peer reviewers VIEW ALL
Senior Staff Physician
Multicultural Dermatology Center
Henry Ford Hospital
Detroit
MI
Disclosures
IH is an author of a number of references cited in this topic.
Chair
Dermatology Department
University of Brescia
Brescia
Italy
Disclosures
PC-P is an author of a number of references cited in this topic.
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