IgA 肾病

最后审阅: 26 八月 2022
最后更新: 01 二月 2022

小结

定义

病史和体格检查

关键诊断因素

  • 血尿
更多 关键诊断因素

其他诊断因素

  • 蛋白尿
  • 高血压
  • 水肿
其他诊断因素

危险因素

  • IgAN 家族史。
  • 男性
  • 年龄为 20 岁至 30 岁
  • 亚洲人/白人/印第安人血统
  • IgA 血管炎
  • 慢性肝病
  • HIV 感染
更多 危险因素

诊断性检查

首要检查

  • 尿液分析
  • 尿液显微镜检查和培养
  • 基础生化检查,包括估算的肾小球滤过率 (GFR)
  • C3 和 C4 补体水平
  • 肾脏超声
  • 计算机体层摄象术 (KUB)
  • 肾脏活检
更多 首要检查

需考虑的检查

  • 软式膀胱镜检查
  • 皮肤活检
更多 需考虑的检查

治疗流程

持续性治疗

低进展风险

中度进展风险

高进展风险

急性肾损伤

撰稿人

作者

Jonathan Barratt, PhD, FRCP

The Mayer Professor of Renal Medicine

Department of Cardiovascular Sciences

University of Leicester

Honorary Consultant Nephrologist

John Walls Renal Unit

Leicester General Hospital

UK

利益声明

JB has consultancies with Alnylam, argenx, Astellas, Calliditas, Chinook, Dimerix, Novartis, Omeros, Travere Therapeutics, Vera Therapeutics and Visterra. He is also an author of a number of references cited in this topic.

See Cheng Yeo, MBBS, M.Med (Int Med), FRCP (London), MD

Adjunct Assistant Professor

Head & Senior Consultant

Department of Renal Medicine

Tan Tock Seng Hospital

Singapore

利益声明

SCY is an author of a reference cited in this topic.

鸣谢

Professor Jonathan Barratt and Dr See Cheng Yeo would like to gratefully acknowledge Dr Hani Bleibel and Dr Chike Nzerue, previous contributors to this topic.

利益声明

HB and CN declare that they have no competing interests.

同行评议者

Richard Lafayette, MD

Associate Professor of Medicine

Nephrology Division

Stanford University Medical Center

Stanford

CA

利益声明

RL declares that he has no competing interests.

Alan Salama, MA, MBBS, PhD, FRCP

Professor of Nephrology

UCL Centre for Nephrology

Royal Free Hospital

London

UK

利益声明

AS declares that he has no competing interests.

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