最近审阅: 1 十一月 2020
最近更新: 01 十一月 2018

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 炎性腰背痛
  • 虹膜炎/葡萄膜炎
  • 附着点炎
  • 于青春期晚期及20余岁时发病
  • 男性
  • AS 阳性家族史

其他诊断因素

  • 疲劳
  • 睡眠障碍
  • 骶髂关节触痛
  • 呼吸困难
  • 腰椎前曲消失
  • 外周关节受累
  • 脊柱后凸
  • 银屑病
  • 炎性肠病的症状

危险因素

  • HLA-B27
  • 内质网氨基肽酶1(ERAP1)以及白介素23受体(IL23R)基因
  • AS 阳性家族史
  • 肺炎克雷伯杆菌

诊断性检查

需考虑的检查

  • HLA-B27
  • 核磁共振成像 (MRI)
  • 颈椎X线(侧位)
  • 腰椎X线(侧位)
  • 胸椎X线(侧位)
  • 超声
更多 需考虑的检查

治疗流程

撰稿人

Consultant

Rheumatology Department

Royal Berkshire NHS Foundation Trust

Reading

UK

利益声明

AC has served on the advisory boards for MSD and Sanofi; contributed to educational events for Janssen, MSD, Novartis, and Celgene; been on the speaker bureau for Janssen, Pfizer, and Novartis; and received travel grants from Abbvie, UCB, and Pfizer to attend educational conferences.

Specialist Registrar in Rheumatology

Royal Berkshire NHS Foundation Trust

Reading

UK

利益声明

JG declares that she has no competing interests.

Dr Antoni Chan and Dr Jessica Gunn would like to gratefully acknowledge Dr Sarah Keidel, Dr Millicent Stone, Dr Raj Sengupta, Dr Athimalaipet V. Ramanan, and Dr Emma Pomeroy, the previous contributors to this topic. SK declares that she has no competing interests. MS is an author of several references cited in this topic. RS declares that he has no competing interests. AR declares that he has no competing interests. EP is an author of a reference cited in this topic.

同行评议者展开全部内容

Professor of Rheumatology

Centre for Rheumatic Diseases

University Department of Medicine

Glasgow Royal Infirmary University Trust

Glasgow

UK

利益声明

RS is an author of a reference cited in this topic.

Consultant Physician and Rheumatologist

Northwick Park Hospital

Harrow

UK

利益声明

AK declares that he has no competing interests.

Consultant

Norfolk and Norwich University Hospital

Norwich and the Cromer & District Hospital

Cromer

UK

利益声明

KG is an author of a reference cited in this topic.

Interventional Spine Physiatrist

Pain Medicine Specialist

Medical Director

Spine Center

Lahey Clinic

Burlington

MA

利益声明

AGC declares that he has no competing interests.

内容使用需遵循免责声明