最近审阅: 26 十月 2020
最近更新: 18 六月 2020

小结

定义

病史和体格检查

关键诊断因素

  • 自我伤害未遂
  • 为缓解疼痛反复应用非处方止痛药
  • 无症状就诊
  • 恶心、呕吐或腹痛
  • 右上腹疼痛和压痛
  • 黄疸
  • 意识模糊、意识水平下降和/或扑翼样震颤

危险因素

  • 自我伤害史
  • 为缓解疼痛而频繁或重复服药的病史
  • 谷胱甘肽缺乏
  • 肝药酶诱导剂(CYP 450 诱导剂)

诊断性检查

首要检查

  • 血清对乙酰氨基酚水平
  • 血清 AST 和 ALT 水平
  • 动脉血 pH 值和乳酸水平
  • 尿素和电解质或肾功能检查
  • 血清凝血酶原时间和 INR
更多 首要检查

需考虑的检查

  • 血清水杨酸水平
  • 尿液药物筛查
更多 需考虑的检查

治疗流程

撰稿人

Assistant Professor

Division of Medical Toxicology

Department of Emergency Medicine

UC Davis Health

CA

利益声明

DKC declares that he has no competing interests.

Consultant in Emergency Medicine

Emergency Department

The Prince Charles Hospital

Brisbane

Queensland

Australia

利益声明

AN declares that he has no competing interests.

Professor Kennon Heard and Dr Alastair Newton would like to gratefully acknowledge Professor Allan R. Mottram, a previous contributor to this topic. ARM declares that he has no competing interests.

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Clinical Faculty

Department of Toxicology

Rocky Mountain Poison & Drug Center

Denver

CO

利益声明

SP declares that he has no competing interests.

Director

Division of Research

Department of Emergency Medicine

Albert Einstein Medical Center

Philadelphia

PA

利益声明

GFOM declares that he has no competing interests.

Associate Professor

Department of Medicine

McGill University

Emergency Physician and Medical Toxicologist

McGill University Health Centre

Medical Toxicologist

Centre Antipoison du Québec

Montreal

Quebec

Canada

利益声明

SG declares that she is an unpaid co-investigator in the Canadian Acetaminophen Overdose Study and unpaid co-chair of the Extracorporeal Treatment In Poisoning workgroup.

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