急性肾盂肾炎

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最后审阅: 4 Nov 2024
最后更新: 12 Jan 2023

小结

定义

病史和体格检查

关键诊断因素

  • 腰部疼痛
  • 肋脊角压痛
  • 发热
  • 出现新的或不同于之前的肌痛,或者流感样症状
  • 存在的危险因素
  • 恶心
  • 呕吐
完整详情

其他诊断因素

  • 耻骨上压痛
  • 心动过速
  • 低血压
完整详情

危险因素

  • 泌尿道感染
  • 糖尿病
  • 压力性尿失禁
  • 尿路异物(例如结石、导管)
  • 解剖性/功能性泌尿系统异常
  • 免疫抑制状态(例如,HIV、移植、化疗、使用皮质类固醇)
  • 妊娠
  • 频繁性交
  • 母亲具有泌尿道感染病史
  • 新的性伴侣
  • 使用杀精剂
  • 年龄 18~50 岁
  • 年龄 60 岁以上
完整详情

诊断性检查

首要检查

  • 尿液分析
  • 尿培养和药敏
  • 全血细胞计数
  • 红细胞沉降率
  • C 反应蛋白
  • 尿素和电解质
  • 肌酐
  • 血培养(在医院)
完整详情

需考虑的检查

  • 肾脏超声
  • 增强 CT 检查
  • 磁共振成像 (MRI)
完整详情

治疗流程

急症处理

无并发症:非妊娠

复杂性:非妊娠

妊娠

撰稿人

专家顾问

Andrew Lewington, BSc (Hons), MBBS, MEd, MD, FRCP

Consultant Renal Physician

Honorary Associate Professor

Nephrology Department

Leeds Teaching Hospitals NHS Trust

Head of MBChB

School of Medicine

University of Leeds

Leeds

UK

利益声明

AL has been the principal applicant/co-applicant for a number of grants including: Engineering and Physical Sciences Research Council Research - Multiplexed AKI biomarker detection with a single molecule biosensor; Leeds Cares - A novel, non-invasive diagnostic approach to assess kidney transplant health through the targeted measurement of biomarkers of kidney injury and immune response in kidney transplant recipients at the Leeds Teaching Hospitals NHS Trust; Kidney Research Yorkshire - Use of enhanced technology to characterise haemodialysis treatment for acute kidney injury (AKI); Bringing It Home - Validation of a micro-sampling technique for measuring tacrolimus and creatinine remotely; and to fund a research nurse; British Renal Society - Renal function assessment with point of care creatinine in diverse populations (RAPID), and several NIHR grants including on a) Improving the quality of post-discharge care following AKI b) An investigation into the use of remote blood sample collection to reduce health inequalities in patients with mental health disorders c) A comparison of remote blood collection devices: a human factor use study d) Defining the characteristics for a novel automatic device to monitor urine output in catheterized patients e) Leeds Medtech and In-vitro Diagnostic Cooperative Grant Extension f) Surgical MedTech Co-operative for the 2019/20 proof-of-principle funding stream g) A pilot investigation into the use of beta-trace protein for residual renal function estimation in haemodialysis h) Application of functional MRI to improve assessment of chronic kidney disease (AFiRM study) i) SuperResPath-Renal: Quantitative super-resolution technology for a fast, decentralised clinical diagnosis of renal pathologies. AL is the co-author of a number of manuscripts including on extracorporeal treatments, AKI, kidney function testing prior to contrast-enhanced CT, plasma exchange and glucocorticoids in severe ANCA-associated vasculitis, COVID-19 rapid diagnostics, multimodal image-guided ablation on management of renal cancer in Von-Hippel-Lindau syndrome, and on a summary of NICE guidance on CKD. AL is the author of several book chapters on nephrology and AKI. AL has received expenses for accommodation and travel for conferences at which he has given lectures, other than those delivered virtually. AL was a member of the AKI Scientific Program Committee for the ISN World Congress of Nephrology 2020-2021 and Chair of this same committee in 2021-2022.

鸣谢

BMJ Best Practice would like to gratefully acknowledge the previous expert contributor, whose work has been retained in parts of the content:

Lynda A. Frassetto, MD

Professor of Medicine

Division of Nephrology

University of California

San Francisco

CA

LAF declares that she has no competing interests.

同行评议者

Shruti Goel, MBBS, FRCP

Consultant Nephrologist

The Hillingdon Hospital NHS Foundation Trust

London

UK

利益声明

SG declares that she has no competing interests.

编辑

Tessa Davis

Section Editor, BMJ Best Practice

Consultant in Paediatric Emergency Medicine

Royal London Hospital

London

UK

利益声明

TD declares that she has no competing interests.

Emma Quigley

Section Editor, BMJ Best Practice

利益声明

EQ declares that she has no competing interests.

Susan Mayor

Lead Section Editor, BMJ Best Practice

利益声明

SM works as a freelance medical journalist and editor, video editorial director and presenter, and communications trainer. In this capacity, she has been paid, and continues to be paid, by a wide range of organisations for providing these skills on a professional basis. These include: NHS organisations, including the National Institute for Health and Care Excellence, NHS Choices, NHS Kidney Care, and others; publishers and medical education companies, including the BMJ Group, the Lancet group, Medscape, and others; professional organisations, including the British Thoracic Oncology Group, the European Society for Medical Oncology, the National Confidential Enquiry into Patient Outcome and Death, and others; charities and patients’ organisations, including the Roy Castle Lung Cancer Foundation and others; pharmaceutical companies, including Bayer, Boehringer Ingelheim, Novartis, and others; and communications agencies, including Publicis, Red Healthcare and others. She has no stock options or shares in any pharmaceutical or healthcare companies; however, she invests in a personal pension, which may invest in these types of companies. She is managing director of Susan Mayor Limited, the company name under which she provides medical writing and communications services.

Rachel Wheeler

Lead Section Editor, BMJ Best Practice

利益声明

RW declares that she has no competing interests.

Annabel Sidwell

Comorbidities Editor, BMJ Best Practice

利益声明

AS declares that she has no competing interests.

Adam Mitchell

Drug Editor, BMJ Best Practice

利益声明

AM declares that he has no competing interests.

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