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类癌综合征

最后审阅: 21 Oct 2024
最后更新: 17 Oct 2023

小结

定义

病史和体格检查

关键诊断因素

  • 腹泻
  • 潮红
完整详情

其他诊断因素

  • 心悸
  • 腹部绞痛
  • 毛细血管扩张
  • 右心衰的体征
  • 心脏杂音
  • 肝肿大
  • 喘鸣
  • 糙皮病
  • 腹部肿块
完整详情

危险因素

  • 遗传性多发性内分泌肿瘤Ⅰ型(MEN-1)综合征
完整详情

诊断性检查

首要检查

  • 血清嗜铬粒蛋白A/B
  • 尿 5-羟吲哚乙酸
  • 生化检查
  • 肝功能检查
  • 全血细胞计数
完整详情

需考虑的检查

  • 胸部、腹部、骨盆和双相肝 CT
  • 支气管镜检查
  • 内镜检查
  • 生长抑素受体显像 ± 生长抑素单光子发射 CT(SPECT)
  • 碘(I)123 间碘苄胍(MIBG)核素显像
  • 组织学
  • PET 扫描
完整详情

治疗流程

持续性治疗

局限性疾病

转移性疾病

撰稿人

作者

Rajaventhan Srirajaskanthan, BSc (Hons), MD (Res), FRCP

Consultant Gastroenterologist

Neuroendocrine Tumour Unit

Kings College Hospital

London

UK

利益声明

RS has received research grants from AAA, Novartis and Ipsen, and has given consultancy advice to Pfizer and Ipsen. RS has engaged in the speaker's bureau for AAA, Ipsen, and Mylan.

Martyn Caplin, BSc, DM, FRCP

Professor

Consultant in Hepatobiliary and Gastroenterology

Neuroendocrine Tumour Unit

Royal Free Hospital

London

UK

利益声明

MC is on the advisory boards for Novartis, Ipsen, Lexicon, and Pfizer; he has also received speaker honoraria from them.

同行评议者

Wail Malaty, MD

Clinical Professor

Department of Family Medicine

University of North Carolina

Chapel Hill

Assistant Program Director

MAHEC Rural Family Medicine Residency

Hendersonville

NC

利益声明

WM declares that he has no competing interests.

Rajesh K. Garg, MD

Instructor in Medicine

Brigham and Women's Hospital

Division of Endocrinology

Diabetes and Hypertension

Boston

MA

利益声明

RKG declares that he has no competing interests.

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