最近审阅: 30 十月 2020
最近更新: 30 十月 2018

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 脾肿大
  • 呼吸短促
  • 左上腹不适或饱胀感
  • 鼻衄
  • 关节痛
  • 胸骨压痛

其他诊断因素

  • 体重减轻
  • 多汗
  • 发热
  • 苍白
  • 青肿
  • 视网膜出血

危险因素

  • 年龄 65~74 岁
  • 电离辐射暴露
  • 男性

诊断性检查

首要检查

  • 全血细胞计数 (FBC)
  • 全部代谢检测
  • 外周血涂片
  • 骨髓活检
  • 细胞遗传学
  • 包括断裂点分析的定量逆转录PCR(qRT-PCR)
  • 荧光原位杂交 (FISH)
更多 首要检查

治疗流程

撰稿人

Honorary Consultant in Haematology

The Christie NHS Foundation Trust

Manchester

UK

利益声明

TS has received travel support and speaker expenses from Novartis, and has served as a consultant to Novartis for development of drugs for indications other than CML.

Dr Tim Somervaille would like to gratefully acknowledge Dr Han Myint and Dr Robert Chen, the previous contributors to this monograph. HM sits on the advisory board of Novartis and Bristol-Myers Squibb, and also does speaking engagements on their behalf. RC declares that he has no competing interests.

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Chief Fellow

Section of Hematology and Oncology

Department of Internal Medicine

Wake Forest University Baptist Medical Center

Winston-Salem

NC

利益声明

RC declares that she has no competing interests.

Professor of Haematology

Royal Liverpool University Hospital

Liverpool

UK

利益声明

None disclosed.

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