最近审阅: 26 十月 2020
最近更新: 08 二月 2018

小结

定义

病史和体格检查

关键诊断因素

  • 呼吸短促和疲乏
  • 淋巴结肿大
  • 脾肿大
  • 肝肿大

其他诊断因素

  • 存在的危险因素
  • B 症状
  • 复发性感染
  • 瘀斑

危险因素

  • 60 岁以上
  • 男性
  • 白种人
  • CLL 家族史

诊断性检查

首要检查

  • 白细胞分类计数
  • 血涂片
  • 血红蛋白
  • 血小板计数
  • 流式细胞仪
更多 首要检查

需考虑的检查

  • 荧光原位杂交 (FISH)
  • 分子遗传学检测分析
  • 直接抗人球蛋白试验 (DAT)
  • 免疫球蛋白水平
  • 骨髓穿刺和环钻活检
  • CT 扫描
更多 需考虑的检查

治疗流程

撰稿人

Consultant Haematologist

Department of Haematology & Stem Cell Transplantation

Birmingham Heartlands Hospital

Birmingham

UK

利益声明

VM declares that she received a consultancy fee from Janssen, and a grant from Takeda for the ASH Annual Meeting 2014.

Consultant Haematologist

Department of Haematology & Stem Cell Transplantation

Birmingham Heartlands Hospital

Birmingham

UK

利益声明

SP declares that he has received consultancy and speaker fees from Janssen, Gilead, AbbVie, Bristol-Myers Squibb, and Takeda.

Dr Vidhya Murthy and Dr Shankaranarayana Paneesha would like to gratefully acknowledge Dr Robert Chen, a previous contributor to this monograph. RC declares that he has no competing interests.

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Consultant Haemato-oncologist

Section of Haemato-Oncology

The Institute of Cancer Research

Sutton

UK

利益声明

DC declares that he has no competing interests.

Associate Professor

Department of Medicine

Case Western Reserve University

Case Comprehensive Cancer Center

Cleveland

OH

利益声明

PFC has received honoraria from Celgene for participation in a speaker bureau, and from Kite Pharma for participation in an advisory board.

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