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卵巢癌

最后审阅: 27 Jun 2024
最后更新: 24 Aug 2023

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 盆腔肿块
  • 腹水
  • 胸膜腔积液
完整详情

其他诊断因素

  • 胃肠道症状
  • 尿急或尿频
  • 症状持续超过3个月
  • 腹胀
  • 盆腔疼痛/腹痛或压迫感
完整详情

危险因素

  • BRCA1基因突变
  • BRCA2基因突变
  • 其他基因突变
  • 年龄增长
  • 卵巢癌家族史
  • 乳腺癌家族史
  • 从未使用复方口服避孕药
  • Lynch综合征
  • 未育
  • 肥胖
  • 激素治疗
  • 子宫内膜异位症
完整详情

诊断性检查

首要检查

  • 盆腔超声检查
  • CA125
  • 组织病理学
完整详情

需考虑的检查

  • 基因检测
  • PET、PET-CT 或 PET/MRI
  • 磁共振成像 (MRI)
  • CT 扫描
  • 生物标志物检测
完整详情

治疗流程

急症处理

适合手术、术中组织学检查证实疾病的患者

不太适合手术、活检证实疾病的患者

持续性治疗

铂类敏感的复发性卵巢癌

铂类耐药复发性疾病或难治性疾病

撰稿人

作者

Sareena Singh, MD

Gynecologic Oncologist

Aultman Medical Group

Northeast Ohio Medical University

Canton

OH

利益声明

SS declares that she has no competing interests.

鸣谢

Dr Sareena Singh would like to gratefully acknowledge Dr Justin C. Chura and Dr Allison E. Axtell, previous contributors to this topic.

利益声明

JCC and AEA declare that they have no competing interests.

同行评议者

Michael P. Hopkins, MD, MEd

Chairman

Obstetrics and Gynecology

Northeast Ohio Universities of Medicine (NEOMED)

Rootstown

OH

利益声明

MPH declares that he has no competing interests.

Ritu Salani, MD

Gynecologic Oncology Fellow

Johns Hopkins Medical Institutions

Baltimore

MD

利益声明

RS declares that she has no competing interests.

Susan A. Davidson, MD

Associate Professor

Chief, Gynecologic Oncology

Department of Obstetrics & Gynecology (UCD)

University of Colorado Cancer Center

Aurora

CO

利益声明

SAD declares that she has no competing interests.

Khadra Galaal, MBChB, MPH, MRCOG

Consultant Gynaecological Oncologist

Northern Gynaecological Oncology Centre

Queen Elizabeth Hospital

Gateshead

UK

利益声明

KG is co-author of a systematic review of follow-up strategies after primary treatment in ovarian cancer. This is not referenced in this topic.

Jill Tseng, MD

Assistant Clinical Professor of Gynecologic Oncology

University of California, Irvine

Orange

CA

利益声明

JT declares that she has no competing interests.

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