小结
定义
病史和体格检查
关键诊断因素
- 存在的危险因素
- 盆腔肿块
- 腹水
- 胸膜腔积液
其他诊断因素
- 胃肠道症状
- 尿急或尿频
- 症状持续超过3个月
- 腹胀
- 盆腔疼痛/腹痛或压迫感
危险因素
- BRCA1基因突变
- BRCA2基因突变
- 其他基因突变
- 年龄增长
- 卵巢癌家族史
- 乳腺癌家族史
- 从未使用复方口服避孕药
- Lynch综合征
- 未育
- 肥胖
- 激素治疗
- 子宫内膜异位症
诊断性检查
首要检查
- 盆腔超声检查
- CA125
- 组织病理学
需考虑的检查
- 基因检测
- PET、PET-CT 或 PET/MRI
- 磁共振成像 (MRI)
- CT 扫描
- 生物标志物检测
治疗流程
适合手术、术中组织学检查证实疾病的患者
不太适合手术、活检证实疾病的患者
铂类敏感的复发性卵巢癌
铂类耐药复发性疾病或难治性疾病
撰稿人
作者
Sareena Singh, MD
Gynecologic Oncologist
Aultman Medical Group
Northeast Ohio Medical University
Canton
OH
利益声明
SS declares that she has no competing interests.
鸣谢
Dr Sareena Singh would like to gratefully acknowledge Dr Justin C. Chura and Dr Allison E. Axtell, previous contributors to this topic.
利益声明
JCC and AEA declare that they have no competing interests.
同行评议者
Michael P. Hopkins, MD, MEd
Chairman
Obstetrics and Gynecology
Northeast Ohio Universities of Medicine (NEOMED)
Rootstown
OH
利益声明
MPH declares that he has no competing interests.
Ritu Salani, MD
Gynecologic Oncology Fellow
Johns Hopkins Medical Institutions
Baltimore
MD
利益声明
RS declares that she has no competing interests.
Susan A. Davidson, MD
Associate Professor
Chief, Gynecologic Oncology
Department of Obstetrics & Gynecology (UCD)
University of Colorado Cancer Center
Aurora
CO
利益声明
SAD declares that she has no competing interests.
Khadra Galaal, MBChB, MPH, MRCOG
Consultant Gynaecological Oncologist
Northern Gynaecological Oncology Centre
Queen Elizabeth Hospital
Gateshead
UK
利益声明
KG is co-author of a systematic review of follow-up strategies after primary treatment in ovarian cancer. This is not referenced in this topic.
Jill Tseng, MD
Assistant Clinical Professor of Gynecologic Oncology
University of California, Irvine
Orange
CA
利益声明
JT declares that she has no competing interests.
鉴别诊断
- 肠易激综合征 (Irritable bowel syndrome, IBS)
- 转移至卵巢
- 子宫内膜异位症
更多 鉴别诊断指南
- NCCN 肿瘤学临床实践指南:遗传性/家族性高危评估:结直肠癌
- 卵巢上皮癌、输卵管癌和原发性腹膜癌的治疗
更多 指南患者教育信息
卵巢癌:如何定义?
卵巢癌:如何有效治疗?
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