最近审阅: 1 十一月 2020
最近更新: 28 九月 2018

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 前列腺特异性抗原 (PSA) 升高

其他诊断因素

  • 夜尿
  • 尿频
  • 排尿犹豫
  • 排尿困难
  • 直肠指检异常
  • 血尿
  • 体重减轻或厌食症
  • 昏睡
  • 骨痛
  • 可触及的淋巴结

危险因素

  • 50 岁以上
  • 黑人
  • 北美或欧洲西北部发病率下降
  • 前列腺癌家族史
  • 膳食脂肪含量高

诊断性检查

首要检查

  • 血清前列腺特异性抗原 (PSA)
  • 睾酮
  • 肝功能检查 (LFT)
  • 全血细胞计数(FBC)
  • 肾功能
  • 前列腺活组织检查
更多 首要检查

需考虑的检查

  • 骨扫描
  • X 线平片检查
  • 盆腔 CT 扫描
  • 盆腔 MRI/直肠内 MRI
更多 需考虑的检查

新兴检查

  • 尿液生物标志物
  • 血清标志物
  • 18F-氟化钠 PET/CT 和 11C-胆碱 PET/CT
  • 前列腺癌抗原 3 (PCA3) 检测
  • TMPRSS2-ERG 融合基因
  • 前列腺健康指数 (PHI)
  • 4K 评分试验
更多 新兴检查

治疗流程

撰稿人

Radiation Oncologist

Richmond Radiation Oncology Associates

Bon Secours Cancer Institute

Richmond

VA

利益声明

TJW declares that he is the principal investigator of an R-21 NIH research grant investigating the tumour-mediated immune responses in African-American men with prostate cancer.

Professor

Department of Radiation Oncology

University of Texas MD Anderson Cancer Center

Houston

TX

利益声明

MSA declares that he has no competing interests.

同行评议者展开全部内容

Clinical Oncology Registrar

St Luke's Cancer Centre

Royal Surrey Hospital

Guildford

Surrey

UK

利益声明

EA has received consultation fees from the following organisations during the past 3 years: Blue Cross/Blue Shield Association, Sanofi-Aventis, Ferring Pharmaceuticals, Pfizer Corporation, American Urological Association, National Institutes of Health, Accreditation Council for Graduate Medical Education, Royal Hallamshire Hospital, Hartford County Medical Association. EA owns shares in Pfizer Pharmaceuticals, Johnson and Johnson, and General Electric Corporation.

Medical Director

UConn Medical Group

University of Connecticut Health Center

Farmington

CT

利益声明

PA declares that he has no competing interests.

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