B 疱疹病毒感染

最后审阅: 26 八月 2022
最后更新: 23 三月 2022

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 发热 (≥37.5 ℃)
  • 流感样症状
  • 感觉异常
  • 感觉过敏
  • 重度持续性头痛
  • 头晕
  • 眼痛
  • 步态障碍
  • 共济失调
  • 复视
  • 激越
  • 假性脑膜炎
  • 肌无力(麻痹)
  • 顽固性呃逆
  • 呼吸困难
  • 上行性或急性弛缓性麻痹
  • 水疱性病变
更多 关键诊断因素

其他诊断因素

  • 恶心/呕吐
  • 结膜炎
  • 皮疹
  • 淋巴结炎
  • 淋巴管炎
  • 腹痛
其他诊断因素

危险因素

  • 职业暴露
  • 前往散养猕猴的国家/地区旅游
  • 将猕猴作为宠物饲养
  • 暴露于与猕猴一起饲养的非猕猴物种
更多 危险因素

诊断性检查

首要检查

  • 血清学
  • 聚合酶链反应 (PCR)
更多 首要检查

需考虑的检查

  • 病毒培养
  • 脑部 MRI
  • 头颅 CT
  • 脑脊液检测
  • 脑电图 (EEG)
  • 脑干听觉诱发电位
  • 躯体感觉诱发电位
  • 动物样本的实验室检测
更多 需考虑的检查

治疗流程

初步治疗

潜在暴露

急症处理

确诊感染和/或有症状

撰稿人

作者

Richard Whitley, MD

Professor of Pediatrics

Professor of Microbiology, Medicine, and Neurosurgery

University of Alabama

Birmingham

AL

利益声明

RW is a retired Board Member for Gilead Sciences, Inc., and a current member of Scientific Advisory Boards or Data Management Committees for Clear Creek Biosciences, Merck, Virios Therapeutics, Visby Medical, Evrys BioSciences, Enochian Biosciences, and Leyden Laboratories.

鸣谢

Professor Richard Whitley would like to gratefully acknowledge Dr D. Scott Schmid, Dr Jeffrey I. Cohen, and Dr Louisa E. Chapman, previous contributors to this topic, and Dr Julia K. Hilliard for her contributions to this topic. Unfortunately, we have been made aware that Dr Louisa E. Chapman is now deceased.

利益声明

JKH, JIC, and LEC are the authors of several references cited in this topic. DSS declared that he had no competing interests. The views included in this topic are those of the authors (DSS and JIC) and do not necessarily represent the views of the Centers for Disease Control and Prevention or the National Institutes of Health.

同行评议者

Anna Maria Geretti, MD, PhD, FRCPath

Professor of Virology and Infectious Diseases

University of Liverpool

Liverpool

UK

利益声明

AMG declares that she has no competing interests.

Deanna Saylor, MD, MHS

Assistant Professor of Neurology

Johns Hopkins University School of Medicine

Baltimore

MD

利益声明

DS has received research funding from the National Institutes of Health, the World Federation of Neurology, and the Johns Hopkins Center for AIDS Research.

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