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嗜酸粒细胞性食管炎

最后审阅: 5 Oct 2024
最后更新: 29 Mar 2023

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 吞咽困难
  • 回避和改变饮食的行为
完整详情

其他诊断因素

  • 烧心
  • 胸部不适
  • 恶心/呕吐
  • 反流
  • 腹痛
  • 生长迟缓
  • 易激惹
完整详情

危险因素

  • EoO 家族史
  • 男性
  • 特应性疾病
  • 儿童和青年成人
  • 白人血统
完整详情

诊断性检查

首要检查

  • 食管胃十二指肠镜检查
  • 食管活检
  • FBC 和分类计数
完整详情

新兴检查

  • 经鼻内镜
  • 食管吞线试验
  • cytosponge
  • 食管生理学检查
  • EoO 诊断性检查

治疗流程

急症处理

初步诊断

持续性治疗

对初始治疗有反应

无反应或复发

撰稿人

作者

Jenny Epstein, MB ChB MRCPCH PhD

Consultant Paediatric Gastroenterologist

Chelsea and Westminster Hospital

London

UK

利益声明

JE is a member of the advisory board for Dr Falk Pharma, manufacturer of Jorveza, a new formulation of budesonide licensed for adults with eosinophilic oesophagitis (EoO), and Nurtricia for infant functional bowel disorders. She has received honoraria from Dr Falk Pharma to speak on EoO and has been sponsored by Dr Falk Pharma, Abbvie and Nutricia to attend national and international meetings. JE is a member of BSPGHAN IBD working group, medical advisor to CICRA and Coeliac UK, member of CCUK IBD working group, member of BSG EoE Guideline development group, member of NICE Guideline update committee for Crohn’s disease and ulcerative colitis, member of NICE Diagnostics, and sits on the NICE advisory committee for personalised treatment in Crohn's disease.

鸣谢

Dr Jenny Epstein wishes to gratefully acknowledge Dr Evan S. Dellon, the previous contributor to this topic.

利益声明

ESD is an author of a number of references cited in this topic.

同行评议者

David Katzka, MD

Professor of Medicine

Mayo Clinic

Rochester

MN

利益声明

DK has served on advisory boards (Adare, Receptos) and received research funding (Covidien).

Alexandra Papadopoulou, MD

Honorary Professor

Chief of the Division of Gastroenterology and Hepatology

First Department of Pediatrics

University of Athens

Agia Sofia Children’s Hospital

Athens

Greece

利益声明

AP has received speaker’s honorariums from Nestle and Nutricia; research grants from Biogaia/Nutricia/Abbvie; consultant’s fee from Receptos.

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