小结
定义
病史和体格检查
关键诊断因素
- 存在的危险因素
- 吞咽困难
- 回避和改变饮食的行为
其他诊断因素
- 烧心
- 胸部不适
- 恶心/呕吐
- 反流
- 腹痛
- 生长迟缓
- 易激惹
危险因素
- EoO 家族史
- 男性
- 特应性疾病
- 儿童和青年成人
- 白人血统
诊断性检查
首要检查
- 食管胃十二指肠镜检查
- 食管活检
- FBC 和分类计数
新兴检查
- 经鼻内镜
- 食管吞线试验
- cytosponge
- 粘膜阻抗
- EoO 诊断性检查
治疗流程
初步诊断
对初始治疗有反应
无反应或复发
撰稿人
作者
Jenny Epstein, MB ChB MRCPCH PhD
Consultant Paediatric Gastroenterologist
Chelsea and Westminster Hospital
London
UK
利益声明
JE is a member of the advisory board for Dr Falk Pharma, manufacturer of Jorveza, a new formulation of budesonide licensed for adults with eosinophilic oesophagitis (EoO), and Nurtricia for infant functional bowel disorders. She has received honoraria from Dr Falk Pharma to speak on EoO and has been sponsored by Dr Falk Pharma, Abbvie and Nutricia to attend national and international meetings. JE is a member of BSPGHAN IBD working group, medical advisor to CICRA and Coeliac UK, member of CCUK IBD working group, member of BSG EoE Guideline development group, member of NICE Guideline update committee for Crohn’s disease and ulcerative colitis, member of NICE Diagnostics, and sits on the NICE advisory committee for personalised treatment in Crohn's disease.
鸣谢
Dr Jenny Epstein wishes to gratefully acknowledge Dr Evan S. Dellon, the previous contributor to this topic.
利益声明
ESD is an author of a number of references cited in this topic.
同行评议者
David Katzka, MD
Professor of Medicine
Mayo Clinic
Rochester
MN
利益声明
DK has served on advisory boards (Adare, Receptos) and received research funding (Covidien).
Alexandra Papadopoulou, MD
Honorary Professor
Chief of the Division of Gastroenterology and Hepatology
First Department of Pediatrics
University of Athens
Agia Sofia Children’s Hospital
Athens
Greece
利益声明
AP has received speaker’s honorariums from Nestle and Nutricia; research grants from Biogaia/Nutricia/Abbvie; consultant’s fee from Receptos.
鉴别诊断
- 胃食管反流病 (GORD)
- 嗜酸细胞性胃肠炎
- 失弛缓症
更多 鉴别诊断指南
- 胃肠镜操作的知情同意指南
- 嗜酸粒细胞性食管炎的临床管理指南
更多 指南
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