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寨卡病毒感染

最后审阅: 1 Nov 2024
最后更新: 18 Aug 2022

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 发热
  • 斑丘疹
  • 关节痛
  • 结膜炎
  • 先天性寨卡综合征的临床特征(婴儿)
  • 吉兰-巴雷综合征的临床特征
完整详情

其他诊断因素

  • 其他全身症状
  • 胃肠道症状
  • 眼眶后疼痛
  • 下肢水肿
  • 成人一过性耳聋
完整详情

危险因素

  • 居住于/曾前往疫区
  • 在疫区被蚊虫叮咬
  • 与感染个体进行无保护性接触
  • 输入来自感染个体的血液
  • 接受感染者的精子捐献
  • 暴露于其他被感染的体液
  • 暴露于被感染的人细胞/组织
完整详情

诊断性检查

首要检查

  • 逆转录聚合酶链反应 (RT-PCR)
  • 血清学
  • 其他虫媒病毒的检测
完整详情

需考虑的检查

  • 产前超声
  • 羊膜腔穿刺术
  • 头围测量(新生儿)
  • 新生儿的进一步评估
  • 头颅 CT/MRI(新生儿)
  • 吉兰-巴雷综合征的检查
完整详情

治疗流程

急症处理

症状性:非妊娠

妊娠:可能经蚊虫传播或经性接触而暴露

先天性寨卡综合征

寨卡相关性吉兰-巴雷综合征

撰稿人

作者

Geraldo Furtado, MD, MSc

Clinical Director

Microcephaly Working Group

Instituto de Medicina Integral Professor Fernando Figueira (IMIP)

Recife

Brazil

利益声明

GF is an author of a reference cited in this topic.

Adriana Scavuzzi, MD, MSc, PhD

Coordinator Obstetrics/Gynecology

Microcephaly Working Group

Instituto de Medicina Integral Professor Fernando Figueira (IMIP)

Recife

Brazil

利益声明

AS declares that she has no competing interests.

同行评议者

William A. Petri, Jr., MD, PhD

Chief

Division of Infectious Diseases and International Health

University of Virginia

Charlottesville

VA

利益声明

WAP declares that he has no competing interests.

Dominic Dwyer, BSc (Med), MBBS, MD, FRACP, FRCPA

Director

Institute of Clinical Pathology and Medical Research

Pathology West

Westmead Hospital

Sydney

Australia

利益声明

DD is a member of Advisory Boards for bioCSL and GSK in antivirals and vaccines.

Chad Achenbach, MD, MPH

Assistant Professor

Division of Infectious Diseases

Northwestern University Feinberg School of Medicine

Chicago

IL

利益声明

CA declares that he has no competing interests.

Henry Wu, MD, DTM&H

Assistant Professor of Medicine

TravelWell Center

Division of Infectious Diseases

Atlanta

GA

利益声明

HW declares that he has no competing interests.

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