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登革热

Last reviewed: 23 Jun 2024
Last updated: 25 Jul 2023

Summary

Definition

History and exam

Key diagnostic factors

  • 存在的危险因素
  • 发热
  • 皮肤潮红/皮疹
  • 肌痛/关节痛/头痛
  • 出血迹象
  • 昏睡/躁动
  • 肝肿大
  • 腹胀
  • 胸膜炎性胸痛,呼吸困难,咳嗽
  • 循环衰竭迹象
Full details

Other diagnostic factors

  • 胃肠道症状
  • 上呼吸道症状
Full details

Risk factors

  • 居住于或在过去 2 周内曾前往登革热疫区旅行
  • 1到5岁儿童
  • 老年
  • 妊娠
  • 合并症的发生
  • 暴露于受感染的血液制品
  • 生活中使用无盖水容器
  • 女性
  • 肥胖
  • O 型血
Full details

Diagnostic tests

1st tests to order

  • 全血细胞计数 (FBC)
  • 肝功能检查 (LFTs)
  • 血清白蛋白水平
  • 血清学
  • 逆转录-聚合酶链反应(RT-PCR)
  • 非结构蛋白1检测(NS1)
Full details

Tests to consider

  • 凝血功能检查
  • 胸部 X 线检查
  • 腹部超声
Full details

Emerging tests

  • 逆转录-绝缘等温聚合酶链反应 (RT-iiPCR)

Treatment algorithm

ACUTE

WHO C组(确定警示征象)

WHO B组(出现警示征象)

WHO A组(无警示征象)

Contributors

Authors

S.A.M. Kularatne, MBBS, MD, MRCP (UK), FRCP (London), FCCP (SL)
S.A.M. Kularatne

Senior Professor

Chair of Medicine

Department of Medicine

Faculty of Medicine

University of Peradeniya

Peradeniya

Sri Lanka

Disclosures

SAMK is an author of several references cited in this topic.

Peer reviewers

John McBride, PhD, MBBS, DTM&H, FRACP, FRCPA

Professor of Medicine

James Cook University

Cairns Base Hospital Clinical School

Cairns

Australia

Disclosures

JM declares that he has no competing interests.

Michael Jacobs, MA, PhD, MBBS, FRCP, DTM&H

Consultant

Infectious Diseases

Royal Free Hampstead NHS Trust

London

UK

Disclosures

MJ declares that he has no competing interests.

Stephen Gluckman, MD

Professor of Medicine

Medical Director

Penn Global Medicine

Penn Center for Primary Care

PA

Disclosures

SG declares that he has no competing interests.

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