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Last reviewed: 22 Sep 2025
Last updated: 03 May 2024

Summary

Definición

Anamnesis y examen

Principales factores de diagnóstico

  • presence of risk factors
  • fever
  • skin flushing/rash
  • myalgia/arthralgia/headache
  • haemorrhagic signs
  • lethargy/restlessness
  • hepatomegaly
  • abdominal distension
  • pleuritic chest pain, dyspnoea, cough
  • signs of circulatory collapse
Todos los datos

Otros factores de diagnóstico

  • gastrointestinal symptoms
  • upper respiratory tract symptoms
Todos los datos

Factores de riesgo

  • residence in/travel from dengue-endemic region within the past 2 weeks
  • children aged 1 to 5 years
  • older age
  • pregnancy
  • presence of comorbidities
  • exposure to infected blood products
  • living with uncovered water container
  • female sex
  • obesity
  • blood group O
Todos los datos

Pruebas diagnósticas

Primeras pruebas diagnósticas para solicitar

  • FBC
  • liver function tests (LFTs)
  • serum albumin level
  • serology
  • reverse transcription-polymerase chain reaction (RT-PCR)
  • non-structural protein 1 (NS1) detection
Todos los datos

Pruebas diagnósticas que deben considerarse

  • coagulation studies
  • chest x-ray
  • abdominal ultrasound
Todos los datos

Pruebas emergentes

  • reverse transcription-insulated isothermal polymerase chain reaction (RT-iiPCR)

Algoritmo de tratamiento

Agudo

WHO group C (established warning signs)

WHO group B (developing warning signs)

WHO group A (no warning signs)

Colaboradores

Autores

S.A.M. Kularatne, MBBS, MD, MRCP (UK), FRCP (London), FCCP (SL)
S.A.M. Kularatne

Senior Professor

Chair of Medicine

Department of Medicine

Faculty of Medicine

University of Peradeniya

Peradeniya

Sri Lanka

Divulgaciones

SAMK is an author of several references cited in this topic.

Revisores por pares

John McBride, PhD, MBBS, DTM&H, FRACP, FRCPA

Professor of Medicine

James Cook University

Cairns Base Hospital Clinical School

Cairns

Australia

Divulgaciones

JM declares that he has no competing interests.

Michael Jacobs, MA, PhD, MBBS, FRCP, DTM&H

Consultant

Infectious Diseases

Royal Free Hampstead NHS Trust

London

UK

Divulgaciones

MJ declares that he has no competing interests.

Stephen Gluckman, MD

Professor of Medicine

Medical Director

Penn Global Medicine

Penn Center for Primary Care

PA

Declarações

SG declares that he has no competing interests.

Créditos aos pareceristas

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Declarações

As afiliações e declarações dos pareceristas referem--se ao momento da revisão.

Referências

Nossas equipes internas de editoria e de evidências trabalham em conjunto com colaboradores internacionais especializados e pares revisores para garantir que forneçamos acesso às informações o mais clinicamente relevantes possível.

Principais artigos

World Health Organization, Regional Office for South-East Asia. Comprehensive guidelines for prevention and control of dengue and dengue haemorrhagic fever - revised and expanded edition. 2011 [internet publication].Texto completo

World Health Organization, Special Programme for Research and Training in Tropical Diseases (TDR). Dengue: guidelines for diagnosis, treatment, prevention and control. New edition. 2009 [internet publication].Texto completo

Guo C, Zhou Z, Wen Z, et al. Global epidemiology of dengue outbreaks in 1990-2015: a systematic review and meta-analysis. Front Cell Infect Microbiol. 2017 Jul 12;7:317.Texto completo  Resumo

Simmons CP, Farrar JJ, Nguyen VV, et al. Dengue. N Engl J Med. 2012;366:1423-1432. Resumo

Artigos de referência

Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
  • Dengue fever images
  • Diagnósticos diferenciais

    • Zika virus infection
    • Chikungunya virus infection
    • Rickettsial diseases
    Mais Diagnósticos diferenciais
  • Diretrizes

    • CDC Yellow Book: health information for international travel - dengue
    • Laboratory testing for Zika virus and dengue virus infections
    Mais Diretrizes
  • Folhetos informativos para os pacientes

    Dengue fever

    Mais Folhetos informativos para os pacientes
  • Videos

    Venepuncture and phlebotomy animated demonstration

    Peripheral venous cannulation animated demonstration

    Mais vídeos
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