最近审阅: 3 十一月 2020
最近更新: 24 五月 2018

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 苍白
  • 黄疸
  • 脾肿大

其他诊断因素

  • 疲劳
  • 胎儿水肿或死胎

危险因素

  • 脾切除术、贫血、黄疸或 HS 家族史
  • 白人血统

诊断性检查

首要检查

  • 全血细胞计数 (FBC)
  • 网织红细胞计数
  • 血涂片
  • 血清胆红素
  • 血清转氨酶
  • 直接抗人球蛋白试验 (DAT)
更多 首要检查

需考虑的检查

  • 伊红-5-马来酰亚胺结合试验
  • 酸化甘油溶解试验
  • 十二烷基硫酸钠-聚丙烯酰胺凝胶电泳
  • 红细胞渗透脆性 (OF) 试验
更多 需考虑的检查

治疗流程

撰稿人

Associate Professor of Pediatrics

University of Arkansas for Medical Sciences

Little Rock

AR

利益声明

SC is on an advisory board for HEMA Biologics for a hemophilia product (unrelated to this article).

Dr Shelley Crary would like to gratefully acknowledge Dr Paula Bolton-Maggs, a previous contributor to this topic. PB-M has received travel and accommodation payments to give a series of lectures on paediatric haematology, one of which was on HS. She also was an expert witness in a legal case concerning a child with HS. PB-M is an author of some references cited in this topic.

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Professor of Medicine Emeritus

School of Medicine and Public Health

University of Wisconsin-Madison

Madison

WI

利益声明

RS is an author of a number of references cited in this monograph.

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