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盘状红斑狼疮

最后审阅: 23 Jun 2024
最后更新: 01 Aug 2023

小结

定义

病史和体格检查

关键诊断因素

  • 红斑状圆形鳞屑性丘疹
  • 年龄为 20 至 40 岁
  • 紫外线暴露史
  • 吸烟史
完整详情

其他诊断因素

  • 无瘙痒和/或疼痛
  • 毛细血管扩张、色素沉着和/或色素减退
  • 永久瘢痕性脱发
  • 全身性表现(关节炎、胸膜炎、心包炎、癫痫发作、精神病)
完整详情

危险因素

  • 年龄为 20 至 40 岁
  • 紫外线辐射
  • 吸烟
  • 女性
  • 非特异性皮肤损伤
完整详情

诊断性检查

首要检查

  • 抗核抗体,双链 (ds) DNA
  • 全血细胞计数(FBC)
  • 红细胞沉降率 (ESR)
  • 尿素和电解质
  • 尿液分析
完整详情

需考虑的检查

  • 皮肤活检
完整详情

治疗流程

持续性治疗

非重度局部/局限性病变

重度或难治的局部/局限性病变;泛发性病变

撰稿人

作者

Meng May Chee, MBChB, MRCP

Consultant Rheumatologist

Wishaw General Hospital

Wishaw

UK

利益声明

MMC declares that she has no competing interests.

Girish Gupta, MBChB, FRCP

Consultant Dermatologist

Lauriston Building

NHS Lothian

Edinburgh

UK

利益声明

GG is an advisory board member of Almirall, Galderma, and Viatris. GG has also been reimbursed for consultancy work by Almirall, Galderma, and AbbVie, and has received honoraria from Almirall, Galderma, Viatris, and La Roche-Posay for giving lectures.

鸣谢

Dr Meng May Chee and Dr Girish Gupta would like to gratefully acknowledge Dr Rajan Madhok, the previous contributor to this topic.

利益声明

RM declared holding shares in GSK to the value of less than £12,000.

同行评议者

Jeffrey P. Callen, MD

Professor of Medicine (Dermatology)

University of Louisville

Louisville

KY

利益声明

JPC declares that he has no competing interests.

Mark Goodfield, MD

Consultant Dermatologist

Department of Dermatology

Leeds General Infirmary

Leeds

UK

利益声明

MG declares that he has no competing interests.

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