小结
定义
病史和体格检查
关键诊断因素
- 红斑状圆形鳞屑性丘疹
- 年龄为 20 至 40 岁
- 紫外线暴露史
- 吸烟史
其他诊断因素
- 无瘙痒和/或疼痛
- 毛细血管扩张、色素沉着和/或色素减退
- 永久瘢痕性脱发
- 全身性表现(关节炎、胸膜炎、心包炎、癫痫发作、精神病)
危险因素
- 年龄为 20 至 40 岁
- 紫外线辐射
- 吸烟
- 女性
- 非特异性皮肤损伤
诊断性检查
首要检查
- 抗核抗体,双链 (ds) DNA
- 全血细胞计数(FBC)
- 红细胞沉降率 (ESR)
- 尿素和电解质
- 尿液分析
需考虑的检查
- 皮肤活检
治疗流程
非重度局部/局限性病变
重度或难治的局部/局限性病变;泛发性病变
撰稿人
作者
Meng May Chee, MBChB, MRCP
Consultant Rheumatologist
Wishaw General Hospital
Wishaw
UK
利益声明
MMC declares that she has no competing interests.
Girish Gupta, MBChB, FRCP
Consultant Dermatologist
Lauriston Building
NHS Lothian
Edinburgh
UK
利益声明
GG is an advisory board member of Almirall, Galderma, and Viatris. GG has also been reimbursed for consultancy work by Almirall, Galderma, and AbbVie, and has received honoraria from Almirall, Galderma, Viatris, and La Roche-Posay for giving lectures.
鸣谢
Dr Meng May Chee and Dr Girish Gupta would like to gratefully acknowledge Dr Rajan Madhok, the previous contributor to this topic.
利益声明
RM declared holding shares in GSK to the value of less than £12,000.
同行评议者
Jeffrey P. Callen, MD
Professor of Medicine (Dermatology)
University of Louisville
Louisville
KY
利益声明
JPC declares that he has no competing interests.
Mark Goodfield, MD
Consultant Dermatologist
Department of Dermatology
Leeds General Infirmary
Leeds
UK
利益声明
MG declares that he has no competing interests.
鉴别诊断
- 系统性红斑狼疮 (SLE)
- 亚急性皮肤红斑狼疮
- 银屑病
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银屑病
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