小结
定义
继发于恶性肿瘤治疗的口腔黏膜炎是在全身化疗和/或累及口腔的放疗后，口腔黏膜出现的急性炎症。临床可表现为大面积红斑性口炎、糜烂及明显溃疡。病损常伴有剧烈疼痛，可能影响进食和口腔卫生，同时增加局部和全身感染风险。如果病情严重，可能需降低化疗剂量和/或暂时停止放疗。因此，黏膜炎是恶性肿瘤治疗重要并发症，可能会影响患者预后。[1]
[Figure caption and citation for the preceding image starts]: 黏膜炎：舌背外侧缘来自 Rajesh V. Lalla (DDS、PhD、CCRP、DABOM) 的教学收藏；经许可后使用 [Citation ends].
[Figure caption and citation for the preceding image starts]: 黏膜炎：颊黏膜来自 Rajesh V. Lalla (DDS、PhD、CCRP、DABOM) 的教学收藏；经许可后使用 [Citation ends].
病史和体格检查
诊断性检查
治疗流程
撰稿人
作者
Rajesh V. Lalla, DDS, PhD, DABOM
Associate Professor
Associate Dean for Research
Section of Oral Medicine
University of Connecticut School of Dental Medicine
Farmington
CT
利益声明
RVL serves as a consultant for Galera Therapeutics, Ingalfarma, Mundipharma and Sucampo Pharma, and has received research funding from Onxeo, Sucampo Pharma, Galera Therapeutics and Novartis.
同行评议者
Michael Brennan, DDS, MHS
Associate Chairman and Oral Medicine Residency Director
Department of Oral Medicine
Carolinas Medical Center
Charlotte
NC
利益声明
MB is an author of a reference cited in this monograph. MB is part of the Mucositis Study Group of MASCC/ISOO, and participated in the review of mucositis.
Maria Michelagnoli, MB ChB, MD, FRCPCH
Consultant Pediatric and Adolescent Oncologist
University College London Hospitals
London
UK
利益声明
MM declares that she has no competing interests.
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